1.
EMBO J
; 41(21): e112415, 2022 11 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36222348
RESUMO
A recent study by Missiaen et al (2022) uncovers hepatocellular carcinoma (HCC) cells to downregulate urea cycle enzymes and rely on the uptake of exogenous arginine and GCN2 kinase-dependent cell-cycle arrest for survival. These results offer new avenues for combinatorial targeting of liver cancer.