RESUMO
The aim of this randomised prospective study was to investigate the impact of preoperative gonadotrophin-releasing hormone agonist (GnRHa) compared with a control group with myomectomy. A total of 36 women (n = 36, group 1) with fibroids were randomised to receive either two monthly doses (n = 18/36, group 1a) or three monthly doses of goserelin (n = 18/36, group 1b) prior to myomectomy. The 32 women who received no treatment (group 2) comprised the controls. All patients had similar demographic features. There were no significant differences among the three groups with respect to: (1) mean intraoperative blood loss; (2) preoperative and postoperative blood transfusion or (3) length of hospital stay. The only advantage of administering GnRHa prior to myomectomy for symptomatic fibroids in our population was a higher haemoglobin level prior to surgery among the women who received three doses of the drug.
Assuntos
Antineoplásicos Hormonais/administração & dosagem , Gosserrelina/administração & dosagem , Leiomioma/tratamento farmacológico , Neoplasias Uterinas/tratamento farmacológico , Adulto , Perda Sanguínea Cirúrgica , Transfusão de Sangue , Esquema de Medicação , Feminino , Hormônio Liberador de Gonadotropina/agonistas , Hemoglobinas/metabolismo , Humanos , Leiomioma/cirurgia , Tempo de Internação , Cuidados Pré-Operatórios , Estudos Prospectivos , Miomectomia Uterina , Neoplasias Uterinas/cirurgiaRESUMO
Birth injuries are devastating to parents and carers alike. They carry the possibility of residual loss of function to the infant and thus the potential for litigation. The aim of this study was to determine the incidence of Erb-Duchenne's palsy and the identification of any contributing factors. A retrospective review over a five-year period, 2005-2009, was performed and an incidence of 0.94 per 1000 live births was noted. An association between both macrosomia and shoulder dystocia and the development of Erb-Duchenne palsy in the newborn was noted. The authors recommended the use of partograms and improved note documentation in the management of labour.
Assuntos
Peso ao Nascer , Neuropatias do Plexo Braquial , Distocia/prevenção & controle , Macrossomia Fetal/diagnóstico , Paralisia Obstétrica , Adulto , Neuropatias do Plexo Braquial/epidemiologia , Neuropatias do Plexo Braquial/etiologia , Neuropatias do Plexo Braquial/fisiopatologia , Pré-Escolar , Parto Obstétrico/efeitos adversos , Parto Obstétrico/métodos , Distocia/etiologia , Feminino , Macrossomia Fetal/complicações , Hospitais de Ensino/estatística & dados numéricos , Humanos , Incidência , Recém-Nascido , Paralisia Obstétrica/epidemiologia , Paralisia Obstétrica/etiologia , Paralisia Obstétrica/fisiopatologia , Gravidez , Estudos Retrospectivos , Ombro/fisiopatologia , Trinidad e Tobago/epidemiologia , Ultrassonografia Pré-Natal/métodosRESUMO
Birth injuries are devastating to parents and carers alike. They carry the possibility of residual loss of function to the infant and thus the potential for litigation. The aim of this study was to determine the incidence of Erb-Duchenne's palsy and the identification of any contributing factors. A retrospective review over a five-year period, 2005-2009, was performed and an incidence of 0.94 per 1000 live births was noted. An association between both macrosomia and shoulder dystocia and the development of Erb-Duchenne palsy in the newborn was noted. The authors recommended the use of partograms and improved note documentation in the management of labour.
Las lesiones de nacimiento resultan devastadoras tanto para los padres como para los cuidadores. Ellos conllevan la posibilidad de pérdida residual de función para el infante y por ende la potencialidad de litigios. El objetivo de este estudio fue determinar la incidencia de la parálisis de Erb Duchenne y la identificación de cualquiera de los factores contribuyentes. Se llevó a cabo una revisión retrospectiva por un periodo de cinco años, 2005-2009, y se observó una incidencia de 0.94 por 1000 nacimientos vivos. Se observó una asociación entre macrosomía y distocia del hombro, por una parte, y el desarrollo de la parálisis de Erb Duchenne, por otra parte, en el recién nacido. Los autores recomendaron usar partogramas y mejorar la documentación de las notas clínicas durante el trabajo de parto.