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1.
J Clin Med ; 13(12)2024 Jun 20.
Artigo em Inglês | MEDLINE | ID: mdl-38930132

RESUMO

Background: This study evaluates the diagnostic accuracy of an AI-assisted tool in assessing the proximity of the mandibular canal (MC) to the root apices (RAs) of mandibular teeth using computed tomography (CT). Methods: This study involved 57 patients aged 18-30 whose CT scans were analyzed by both AI and human experts. The primary aim was to measure the closest distance between the MC and RAs and to assess the AI tool's diagnostic performance. The results indicated significant variability in RA-MC distances, with third molars showing the smallest mean distances and first molars the greatest. Diagnostic accuracy metrics for the AI tool were assessed at three thresholds (0 mm, 0.5 mm, and 1 mm). Results: The AI demonstrated high specificity but generally low diagnostic accuracy, with the highest metrics at the 0.5 mm threshold with 40.91% sensitivity and 97.06% specificity. Conclusions: This study underscores the limited potential of tested AI programs in reducing iatrogenic damage to the inferior alveolar nerve (IAN) during dental procedures. Significant differences in RA-MC distances between evaluated teeth were found.

2.
J Clin Med ; 13(5)2024 Mar 05.
Artigo em Inglês | MEDLINE | ID: mdl-38592413

RESUMO

Background: Temporomandibular joint disorder (TMD) is a common medical condition. Cone beam computed tomography (CBCT) is effective in assessing TMD-related bone changes, but image noise may impair diagnosis. Emerging deep learning reconstruction algorithms (DLRs) could minimize noise and improve CBCT image clarity. This study compares standard and deep learning-enhanced CBCT images for image quality in detecting osteoarthritis-related degeneration in TMJs (temporomandibular joints). This study analyzed CBCT images of patients with suspected temporomandibular joint degenerative joint disease (TMJ DJD). Methods: The DLM reconstructions were performed with ClariCT.AI software. Image quality was evaluated objectively via CNR in target areas and subjectively by two experts using a five-point scale. Both readers also assessed TMJ DJD lesions. The study involved 50 patients with a mean age of 28.29 years. Results: Objective analysis revealed a significantly better image quality in DLM reconstructions (CNR levels; p < 0.001). Subjective assessment showed high inter-reader agreement (κ = 0.805) but no significant difference in image quality between the reconstruction types (p = 0.055). Lesion counts were not significantly correlated with the reconstruction type (p > 0.05). Conclusions: The analyzed DLM reconstruction notably enhanced the objective image quality in TMJ CBCT images but did not significantly alter the subjective quality or DJD lesion diagnosis. However, the readers favored DLM images, indicating the potential for better TMD diagnosis with CBCT, meriting more study.

3.
J Chromatogr A ; 1505: 1-17, 2017 Jul 07.
Artigo em Inglês | MEDLINE | ID: mdl-28533027

RESUMO

Analysis of trace compounds in complex matrices requires a preliminary step of sample preparation. From among widely used methodologies, microextraction techniques have become increasingly important as they tend towards being environmentally friendly. The needle trap (NT) extraction is a relatively new and promising technique which combines sampling, sample preparation and sample introduction. The core of the needle trap device is a suitable sorbent material packed inside the needle, that determines selectivity and efficiency of the method. In recent years, the effort towards improvement of needle trap extraction performance has led to development of new extraction media with higher selectivity and better adsorption properties, which may facilitate preconcentration of the target analytes. In this work, we present a review on the trends in development of sorbent materials used in the needle trap device including fibrous media, commercially available materials as well as sorbents prepared for special applications. This review also describes recent developments in the needle trap devices such as needle geometries, sorbent packing procedure and sampling methodologies. Comparison of needle trap extraction and solid phase microextraction (SPME) is presented to demonstrate the robustness of the former.


Assuntos
Microextração em Fase Sólida/instrumentação , Adsorção , Agulhas , Microextração em Fase Sólida/métodos , Microextração em Fase Sólida/tendências
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