[Structural changes in the stomach, duodenum and pancreas in ischemic heart disease]. / Strukturnye izmeneniia zheludka, dvenadtsatiperstnoi kishki i podzheludochnoi zhelezy pri ishemicheskoi bolezni serdtsa.

The authors carried out a morphological, histochemical and morphometric study of the gastric mucosa, duodenum and pancreas in 22 cadavers of patients who suffered of chronic ischemic heart disease. It was established that patients with chronic ischemic heart disease develop dystrophic, atrophic, sclerotic and compensatory-adaptative changes that may lead to marked structural-functional reorganization of the tissues. The morphological basis of trophic disorders are pronounced disturbances of the intramural microcirculatory bed. Changes were revealed of the morphology of the insular apparatus of the pancreas evidencing inclusion of the endocrinous component in the pathogenesis of chronic ischemic heart disease.

[Changes in the intraorganic blood vessels of the stomach and duodenum in peptic ulcer]. / Izmeneniia vnutriorgannykh krovenosnykh sosudov zheludka i dvenadtsatiperstnoi kishki pri iazvennoi bolezni.

It was established that the ulceration zones showed hyperemia which increases the volume density of venous vessels, disturbs the permeability of their walls, causes trophic disorders with subsequent phlebosclerosis, limitation of capacitance, appearance of venous hypertension and further changes of the vessel wall structures and neighbouring tissues. Compensatory reaction of the arterial intraorganic bed (vascular spasm) deteriorates trophic disorders. Simultaneous increase of the volume density of arterial vessels in the "intact" zone favours reparative and compensatory capacities of the latter. Repeat ulcer formation and chronic course of the disease furthers development of hemo- and microcirculatory disorders, progressing of angio- and perivascular sclerosis, reorganization of the intramural gastric and duodenal vascular bed.