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1.
Sci Rep ; 14(1): 8799, 2024 Apr 16.
Artigo em Inglês | MEDLINE | ID: mdl-38627447

RESUMO

Wireless sensor networks (WSNs) encounter a significant challenge in ensuring network security due to their operational constraints. This challenge stems from the potential infiltration of malware into WSNs, where a single infected node can rapidly propagate worms to neighboring nodes. To address this issue, this research introduces a stochastic S E I R S model to characterize worm spread in WSNs. Initially, we established that our model possesses a globally positive solution. Subsequently, we determine a threshold value for our stochastic system and derive a set of sufficient conditions that dictate the persistence or extinction of worm spread in WSNs based on the mean behavior. Our study reveals that environmental randomness can impede the spread of malware in WSNs. Moreover, by utilizing various parameter sets, we obtain approximate solutions that showcase these precise findings and validate the effectiveness of the proposed S E I R S model, which surpasses existing models in mitigating worm transmission in WSNs.

2.
Materials (Basel) ; 17(2)2024 Jan 18.
Artigo em Inglês | MEDLINE | ID: mdl-38255627

RESUMO

The advanced science and technology of polymer matrix nanomaterials are rapidly developing fields that focus on the synthesis, characterization, and application of nanomaterials in polymer matrices [...].

3.
Materials (Basel) ; 16(24)2023 Dec 05.
Artigo em Inglês | MEDLINE | ID: mdl-38138659

RESUMO

A multifunctional microwave absorber with high thermal conductivity for 5G base station packaging comprising silylated GO/FeSiAl epoxy composites were fabricated by a simple solvent-handling method, and its microwave absorption properties and thermal conductivity were presented. It could act as an applicable microwave absorber for highly integrated 5G base station packaging with 5G antennas within a range of operating frequency of 2.575-2.645 GHz at a small thickness (2 mm), as evident from reflection loss with a maximum of -48.28 dB and an effective range of 3.6 GHz. Such a prominent microwave absorbing performance results from interfacial polarization resonance attributed to a nicely formed GO/FeSiAl interface through silylation. It also exhibits a significant enhanced thermal conductivity of 1.6 W/(mK) by constructing successive thermal channels.

4.
Materials (Basel) ; 16(16)2023 Aug 09.
Artigo em Inglês | MEDLINE | ID: mdl-37629842

RESUMO

Polymer matrix nanomaterials have revolutionized materials science due to their unique properties resulting from the incorporation of nanoscale fillers into polymer matrices [...].

5.
Comput Methods Biomech Biomed Engin ; 26(2): 138-159, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-35297714

RESUMO

A stochastic epidemic model with random noise transmission is taken into account, describing the dynamics of the measles viral infection. The basic reproductive number is calculated corresponding to the stochastic model. It is determined that, given initial positive data, the model has bounded, unique, and positive solution. Additionally, utilizing stochastic Lyapunov functional theory, we study the extinction of the disease. Stationary distribution and extinction of the infection are examined by providing sufficient conditions. We employed optimal control principles and examined stochastic control systems to regulate the transmission of the virus using environmental factors. Graphical representations have been offered for simplicity of comprehending in order to further verify the acquired analytical findings.


Assuntos
Epidemias , Sarampo , Humanos , Simulação por Computador , Processos Estocásticos , Modelos Biológicos , Sarampo/epidemiologia , Sarampo/prevenção & controle
6.
Comput Methods Biomech Biomed Engin ; 26(9): 1086-1099, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-35951001

RESUMO

In this article, we study the dynamics of Norovirus infection by developing a stochastic epidemic model having Levy noise. The study shows that Levy noise and informative interventions have more influence on the said dynamics. Firstly, we show that the model has a unique global positive solution. After this, we formulated a stochastic threshold value as a necessary condition for the extinction and persistence in the mean of the proposed epidemic model. Finally, numerical simulation are drawn to verify our obtained results of the dynamics. The perturbed stochastic approach may affect the dynamical properties of the model and large noises will be greatly significant to minimize its transmission.


Assuntos
Processos Estocásticos , Simulação por Computador
7.
Sci Rep ; 12(1): 18178, 2022 10 28.
Artigo em Inglês | MEDLINE | ID: mdl-36307434

RESUMO

The global consequences of Coronavirus (COVID-19) have been evident by several hundreds of demises of human beings; hence such plagues are significantly imperative to predict. For this purpose, the mathematical formulation has been proved to be one of the best tools for the assessment of present circumstances and future predictions. In this article, we propose a fractional epidemic model of coronavirus (COVID-19) with vaccination effects. An arbitrary order model of COVID-19 is analyzed through three different fractional operators namely, Caputo, Atangana-Baleanu-Caputo (ABC), and Caputo-Fabrizio (CF), respectively. The fractional dynamics are composed of the interaction among the human population and the external environmental factors of infected peoples. It gives an extra description of the situation of the epidemic. Both the classical and modern approaches have been tested for the proposed model. The qualitative analysis has been checked through the Banach fixed point theory in the sense of a fractional operator. The stability concept of Hyers-Ulam idea is derived. The Newton interpolation scheme is applied for numerical solutions and by assigning values to different parameters. The numerical works in this research verified the analytical results. Finally, some important conclusions are drawn that might provide further basis for in-depth studies of such epidemics.


Assuntos
COVID-19 , Humanos , COVID-19/epidemiologia , Pandemias/prevenção & controle , Vacinação , Matemática
8.
Nanomicro Lett ; 14(1): 173, 2022 Aug 23.
Artigo em Inglês | MEDLINE | ID: mdl-35999287

RESUMO

Realizing ultra-wideband absorption, desirable attenuation capability at high temperature and mechanical requirements for real-life applications remains a great challenge for microwave absorbing materials. Herein, we have constructed a porous carbon fiber/polymethacrylimide (CP) structure for acquiring promising microwave absorption performance and withstanding both elevated temperature and high strength in a low density. Given the ability of porous structure to induce desirable impedance matching and multiple reflection, the absorption bandwidth of CP composite can reach ultra-wideband absorption of 14 GHz at room temperature and even cover the whole X-band at 473 K. Additionally, the presence of imide ring group in polymethacrylimide and hard bubble wall endows the composite with excellent heat and compressive behaviors. Besides, the lightweight of the CP composite with a density of only 110 mg cm-3 coupled with high compressive strength of 1.05 MPa even at 453 K also satisfies the requirements in engineering applications. Compared with soft and compressible aerogel materials, we envision that the rigid porous foam absorbing material is particularly suitable for environmental extremes.

9.
Materials (Basel) ; 15(14)2022 Jul 06.
Artigo em Inglês | MEDLINE | ID: mdl-35888202

RESUMO

Nanotechnology has witnessed an incredible resonance and a substantial number of new applications in various areas during the past three decades [...].

10.
Materials (Basel) ; 15(14)2022 Jul 13.
Artigo em Inglês | MEDLINE | ID: mdl-35888341

RESUMO

Commercial polyolefin separators exhibit problems including shrinkage under high temperatures and poor electrolyte wettability and uptake, resulting in low ionic conductivity and safety problems. In this work, core-shell silica-polyphosphazene nanoparticles (SiO2@PZS) with different PZS layer thicknesses were synthesized and coated onto both sides of polyethylene (PE) microporous membranes to prepare composite membranes. Compared to pure silica-coated membranes and PE membranes, the PE-SiO2@PZS composite membrane had higher ionic conductivity. With the increase in the SiO2@PZS shell thickness, the electrolyte uptake, ionic conductivity and discharge capacity gradually increased. The discharge capacity of the PE-SiO2@PZS composite membrane at 8 C rate was 129 mAh/g, which was higher than the values of 107 mAh/g for the PE-SiO2 composite membrane and 104 mAh/g for the PE membrane.

11.
Comput Methods Biomech Biomed Engin ; 25(16): 1852-1869, 2022 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-35234550

RESUMO

We investigate the dynamical behavior of Coronavirus (COVID-19) for different infections phases and multiple routes of transmission. In this regard, we study a COVID-19 model in the context of fractal-fractional order operator. First, we study the COVID-19 dynamics with a fractal fractional-order operator in the framework of Atangana-Baleanu fractal-fractional operator. We estimated the basic reduction number and the stability results of the proposed model. We show the data fitting to the proposed model. The system has been investigated for qualitative analysis. Novel numerical methods are introduced for the derivation of an iterative scheme of the fractal-fractional Atangana-Baleanu order. Finally, numerical simulations are performed for various orders of fractal-fractional dimension.


Assuntos
COVID-19 , Fractais , Humanos , COVID-19/epidemiologia
12.
J Biol Dyn ; 16(1): 236-253, 2022 12.
Artigo em Inglês | MEDLINE | ID: mdl-35341468

RESUMO

In this paper, we consider the dynamical behaviour of a stochastic coronavirus (COVID-19) susceptible-infected-removed epidemic model with the inclusion of the influence of information intervention and Lévy noise. The existence and uniqueness of the model positive solution are proved. Then, we establish a stochastic threshold as a sufficient condition for the extinction and persistence in mean of the disease. Based on the available COVID-19 data, the parameters of the model were estimated and we fit the model with real statistics. Finally, numerical simulations are presented to support our theoretical results.


Assuntos
COVID-19 , Epidemias , COVID-19/epidemiologia , Simulação por Computador , Humanos , Modelos Biológicos , Processos Estocásticos
13.
Sci Rep ; 11(1): 24360, 2021 12 21.
Artigo em Inglês | MEDLINE | ID: mdl-34934111

RESUMO

In this paper, we investigate an norovirus (NoV) epidemic model with stochastic perturbation and the new definition of a nonlocal fractal-fractional derivative in the Atangana-Baleanu-Caputo (ABC) sense. First we present some basic properties including equilibria and the basic reproduction number of the model. Further, we analyze that the proposed stochastic system has a unique global positive solution. Next, the sufficient conditions of the extinction and the existence of a stationary probability measure for the disease are established. Furthermore, the fractal-fractional dynamics of the proposed model under Atangana-Baleanu-Caputo (ABC) derivative of fractional order "[Formula: see text]" and fractal dimension "[Formula: see text]" have also been addressed. Besides, coupling the non-linear functional analysis with fixed point theory, the qualitative analysis of the proposed model has been performed. The numerical simulations are carried out to demonstrate the analytical results. It is believed that this study will comprehensively strengthen the theoretical basis for comprehending the dynamics of the worldwide contagious diseases.


Assuntos
Infecções por Caliciviridae/epidemiologia , Infecções por Caliciviridae/transmissão , Modelos Teóricos , Norovirus/fisiologia , Vacinação/métodos , Infecções por Caliciviridae/prevenção & controle , Infecções por Caliciviridae/virologia , Humanos , Incidência , Processos Estocásticos
14.
FEBS Lett ; 592(7): 1135-1149, 2018 04.
Artigo em Inglês | MEDLINE | ID: mdl-29453883

RESUMO

Gene transcription is often controlled by multiple interacting signal pathways, but how these pathways impact gene expression is not fully understood. Here, we refine a mechanic model based on experiments in murine embryonic stem cells and analyze the influence of pathway-pathway cross-talk strength (CTS) on mRNA expression stability. We find that the CTS can tune this stability, depending on the manner of regulation. Furthermore, there is an optimal CTS such that the expression pattern is most stable but free energy consumption is at its highest; the CTS can induce stochastic focusing of the mRNA level but this is at the cost of energy. In both cases, there is a cross-talk-mediated trade-off, implying that entangled signal pathways can control both expression stability and energy dissipation.


Assuntos
Regulação da Expressão Gênica/fisiologia , Modelos Biológicos , Células-Tronco Embrionárias Murinas/metabolismo , RNA Mensageiro/biossíntese , Transdução de Sinais/fisiologia , Animais , Camundongos , Células-Tronco Embrionárias Murinas/citologia , Processos Estocásticos
15.
RSC Adv ; 8(51): 29344-29355, 2018 Aug 14.
Artigo em Inglês | MEDLINE | ID: mdl-35547984

RESUMO

This study presents the systematic potential effects of reaction parameters on the synthesis of Co-doped ZnNi ferrite/polyaniline composites prepared via novel interfacial polymerization. Through intensive experiments and analysis, optimum reaction conditions including the polymerization temperature and reaction time are proposed so that the performance of the material is significantly improved. The structure, functional groups and morphologies of composites are investigated by X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), Fourier transform-infrared (FT-IR) spectroscopy, scanning electron microscopy (SEM) and high resolution transmission electron microscopy (HRTEM). In addition, the electromagnetic properties and microwave absorption properties of Co-doped ZnNi ferrite/polyaniline composites are examined by a vibrating sample magnetometer (VSM), Quantum Design (MPMS-VSM and MPMS-XL), the superconducting quantum interference device (SQUID) magnetometer and vector network analysis. Based on these analyses, it is found that by tuning the reaction conditions, i.e., polymerization temperature and reaction time, microwave absorption capabilities in terms of the maximum reflection loss (R L) value and absorber thickness can be readily optimized. The results show that the composite with an optimized polymerization condition of 20 °C for 12 h displays remarkable microwave absorption properties with maximum reflectivity of -54.3 dB, and the effective bandwidth (R L < -10 dB) is about 6.02 GHz at a thickness of 6.8 mm. Furthermore, the discussion shows that the promising microwave absorption may be due to the uniform urchin-like structure of the composites.

16.
Sci Rep ; 7(1): 12610, 2017 10 03.
Artigo em Inglês | MEDLINE | ID: mdl-28974770

RESUMO

From the viewpoint of thermodynamics, the formation of DNA loops and the interaction between them, which are all non-equilibrium processes, result in the change of free energy, affecting gene expression and further cell-to-cell variability as observed experimentally. However, how these processes dissipate free energy remains largely unclear. Here, by analyzing a mechanic model that maps three fundamental topologies of two interacting DNA loops into a 4-state model of gene transcription, we first show that a longer DNA loop needs more mean free energy consumption. Then, independent of the type of interacting two DNA loops (nested, side-by-side or alternating), the promotion between them always consumes less mean free energy whereas the suppression dissipates more mean free energy. More interestingly, we find that in contrast to the mechanism of direct looping between promoter and enhancer, the facilitated-tracking mechanism dissipates less mean free energy but enhances the mean mRNA expression, justifying the facilitated-tracking hypothesis, a long-standing debate in biology. Based on minimal energy principle, we thus speculate that organisms would utilize the mechanisms of loop-loop promotion and facilitated tracking to survive in complex environments. Our studies provide insights into the understanding of gene expression regulation mechanism from the view of energy consumption.


Assuntos
DNA/química , Metabolismo Energético/genética , Conformação de Ácido Nucleico , Termodinâmica , DNA/genética , Regulação da Expressão Gênica/genética , Regiões Operadoras Genéticas/genética , Regiões Promotoras Genéticas
17.
ACS Appl Mater Interfaces ; 9(19): 16404-16416, 2017 May 17.
Artigo em Inglês | MEDLINE | ID: mdl-28459536

RESUMO

In this work, two novel flowerlike NiO hierarchical structures, rose-flower (S1) and silk-flower (S2), were synthesized by using a facial hydrothermal method, coupled with subsequent postannealing process. Structures, morphologies, and magnetic and electromagnetic properties of two NiO structures have been systematically investigated. SEM and TEM results suggested that S1 had a hierarchical rose-flower architecture with diameters in the range of 4-7 µm, whereas S2 exhibited a porous silk-flower architecture with diameters of 0.7-1.0 µm. Electromagnetic performances indicated that the NiO hierarchical structures played a crucial role in determining their dielectric behavior and impedance matching characteristic, which further influenced the microwave attenuation property of absorbers based on them. Due to its hierarchical and porous architectures, S2 had higher microwave absorption performances than S1. The maximum RL value for sample S2 can reach -65.1 dB at 13.9 GHz, while an efficient bandwidth of 3 GHz was obtained. In addition, the mechanism of the improved microwave absorption were discussed in detail. It is expected that our NiO hierarchical structures synthesized in this work could be used as a reference to design novel microwave absorption materials.

18.
Sci Rep ; 7: 42128, 2017 02 08.
Artigo em Inglês | MEDLINE | ID: mdl-28176840

RESUMO

Experimental evidence supports that signaling pathways can induce different dynamics of transcription factor (TF) activation, but how an input signal is encoded by such a dynamic, noisy TF and further decoded by downstream genes remains largely unclear. Here, using a system of stochastic transcription with signal regulation, we show that (1) keeping the intensity of the signal noise invariant but prolonging the signal duration can both enhance the mutual information (MI) and reduce the energetic cost (EC); (2) if the signal duration is fixed, the larger MI needs the larger EC, but if the signal period is fixed, there is an optimal time that the signal spends at one lower branch, such that MI reaches the maximum; (3) if both the period and the duration are simultaneously fixed, increasing the input noise can always enhance MI in the case of transcription regulation rather than in the case of degradation regulation. In addition, we find that the input noise can induce stochastic focusing in a regulation-dependent manner. These results reveal not only the dynamic mechanism of noisy signal decoding in gene regulation but also the essential role of external noise in controlling gene expression levels.


Assuntos
Algoritmos , Metabolismo Energético/genética , Regulação da Expressão Gênica , Modelos Genéticos , Fatores de Transcrição/genética , Bacillus subtilis/genética , Bacillus subtilis/metabolismo , Humanos , Saccharomyces cerevisiae/genética , Saccharomyces cerevisiae/metabolismo , Transdução de Sinais , Razão Sinal-Ruído , Fatores de Transcrição/metabolismo , Transcrição Gênica , Células Tumorais Cultivadas
19.
Phys Rev E ; 93(5): 052411, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-27300928

RESUMO

Biotechnology advances have allowed investigation of heterogeneity of cellular responses to stimuli on the single-cell level. Functionally, this heterogeneity can compromise cellular responses to environmental signals, and it can also enlarge the repertoire of possible cellular responses and hence increase the adaptive nature of cellular behaviors. However, the mechanism of how this response heterogeneity is generated remains elusive. Here, by systematically analyzing a representative cellular signaling system, we show that (1) the upstream activator always amplifies the downstream burst frequency (BF) but the noiseless activator performs better than the noisy one, remarkably for small or moderate input signal strengths, and the repressor always reduces the downstream BF but the difference in the reducing effect between noiseless and noise repressors is very small; (2) both the downstream burst size and mRNA mean are a monotonically increasing function of the activator strength but a monotonically decreasing function of the repressor strength; (3) for repressor-type input, there is a noisy signal strength such that the downstream mRNA noise arrives at an optimal level, but for activator-type input, the output noise intensity is fundamentally a monotonically decreasing function of the input strength. Our results reveal the essential mechanisms of both signal information decoding and cellular response heterogeneity, whereas our analysis provides a paradigm for analyzing dynamics of noisy biochemical signaling systems.


Assuntos
Expressão Gênica , Modelos Biológicos , Simulação de Dinâmica Molecular , Transdução de Sinais
20.
Chaos ; 26(4): 043108, 2016 04.
Artigo em Inglês | MEDLINE | ID: mdl-27131487

RESUMO

Expression noise results in cell-to-cell variability in expression levels, and feedback regulation may complicate the tracing of sources of this noise. Using a representative model of gene expression with feedbacks, we analytically show that the expression noise (or the total noise) is decomposed into three parts: feedback-dependent promoter noise determined by a continuous approximation, birth-death noise determined by a simple Poisson process, and correlation noise induced by feedbacks. We clarify confused relationships between feedback and noise in previous studies, by showing that feedback-regulated noisy sources have different contributions to the total noise in different cases of promoter switching (it is an essential reason resulting in confusions). More importantly, we find that there is a tradeoff between response time and expression noise. In addition, we show that in contrast to single feedbacks, coupled positive and negative feedbacks can perform better in tuning expression noise, controlling expression levels, and maintaining response time. The overall analysis implies that living organisms would utilize coupled positive and negative feedbacks for better survival in complex and fluctuating environments.


Assuntos
Retroalimentação Fisiológica , Regiões Promotoras Genéticas
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