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1.
Front Psychol ; 14: 1268480, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38022931

RESUMO

Introduction: Understanding the factors that affected academic performance of students during the COVID-19 pandemic will help design effective interventions for improving students' academic performance during emergency situations as well as during regular academic environment. This cross-sectional study aimed to identify the factors that explain academic performance of students in China during the pandemic. Methods: Data on college students from the 2020 China Family Panel Studies were used, and the final sample consisted of 728 students. Ordered probit regression models were estimated to explain students' relative performance in the semester when the in-person classes were suspended by using various student and household-related variables and characteristics. To compute missing values in selected variables, a multiple imputation technique was applied. Results: The odds of poor academic performance declined with higher Internet use for academic purposes, but Internet use for entertainment increased the probability of being in the poor academic performance. College students who spent more time studying on college work were less likely to have poor academic performance. Discussion: This study identified the factors (Internet use and study time) associated with academic performance among Chinese college students during the COVID-19 pandemic. These results can be used to design policies to improve educational outcomes and to address educational inequalities.

2.
BMC Med Res Methodol ; 23(1): 138, 2023 06 13.
Artigo em Inglês | MEDLINE | ID: mdl-37312061

RESUMO

BACKGROUND: The Behavioral Risk Factor Surveillance System (BRFSS) is an annual survey designed to identify trends in the public's health. In its 2019 field survey, the U.S. state of GA tested a new 3 - item module to measure the numbers of bereaved, resident adults aged 18 years and older. Participants were eligible if they answered 'Yes' to the item 'Have you experienced the death of a family member or close friend in the years 2018 or 2019?'. This analysis explores two research questions. Can estimates for bereavement prevalence be derived without large sampling errors, low precision, and small subsamples? Can multiple imputation techniques be applied to overcome non-response and missing data to support multivariate modeling? METHODS: BRFSS is a non-institutionalized sample of adults aged 18 years and older living in the U.S. state of Georgia. Analyses in this study were conducted under two scenarios. Scenario 1 applies the complex sample weights created by the Centers for Disease Control and imputes values for missing responses. Scenario 2 treats the data as a panel - no weighting combined with removal of persons with missing data. Scenario 1 reflects the use of BRFSS data for public health and policy, while Scenario 2 reflects data as it is commonly used in social science research studies. RESULTS: The bereavement screening item has a response rate (RR) of 69.1% (5206 of 7534 persons). Demographic subgroups and categories of health have RR of 55% or more. Under Scenario 1, the estimated prevalence of bereavement is 45.38%, meaning that 3,739,120 adults reported bereaved in 2018 or 2019. The estimated prevalence is 46.02% with Scenario 2 which removes persons with any missing data (4,289 persons). Scenario 2 overestimates the bereavement prevalence by 1.39%. An illustrative logistic model is presented to show the performance of exposure to bereavement under the two data scenarios. CONCLUSIONS: Recent bereavement can be ascertained in a surveillance survey accounting for biases in response. Estimating bereavement prevalence is needed for measuring population health. This survey is limited to one US state in a single year and excludes persons aged 17 years and younger.


Assuntos
Luto , Adulto , Humanos , Sistema de Vigilância de Fator de Risco Comportamental , Georgia/epidemiologia , Prevalência , Família
3.
Artigo em Inglês | MEDLINE | ID: mdl-37239563

RESUMO

BACKGROUND: Binge drinking is a pattern of alcohol abuse. Its prevalence and associated risk factors are not well documented. Heavy drinking, on the other hand, has a well-documented association with bereavement. This report uses a cross-sectional, population-based survey to estimate prevalence of bingeing and its association with new bereavement. Bingeing is defined as 4 or more drinks (women) or 5 or more drinks (men) in a 2-4-h setting. For the first time in 2019, the Georgia Behavioral Risk Factor Surveillance Survey (BRFSS) included a bereavement item: 'Have you experienced the death of a family member or close friend in the years 2018 or 2019?' METHODS: Georgia BRFSS is a complex sampling survey administered annually. It is designed to represent the 8.1 million people aged 18 years and older in the U.S. state of Georgia. Alcohol consumption patterns are routinely measured in the common core. In 2019, the state added a new item probing for bereavement in the prior 24 months predating the COVID-19 pandemic. Imputation and weighting techniques were applied to yield the population prevalence rates of new bereavement, bingeing, and their co-occurrence with other high-risk health behaviors and outcomes. Multivariate models, adjusted for age, gender, and race, were used to estimate the risk for other unhealthy behaviors posed by the co-occurrence of bereavement and bingeing. RESULTS: In Georgia, bereavement (45.8%), and alcohol consumption (48.8%) are common. Bereavement and alcohol use co-occurred among 1,796,817 people (45% of all drinkers) with a subset of 608,282 persons reporting bereavement combined with bingeing. The most common types of bereavement were death of a friend/neighbor (30.7%) or three plus deaths (31.8%). CONCLUSIONS: While bingeing is a known risk to public health, its co-occurrence with recent bereavement is a new observation. Public health surveillance systems need to monitor this co-occurrence to protect both individual and societal health. In a time of global bereavement, documenting its influence on binge drinking can support the work towards Sustainable Development Goal #3-Good health and Well-Being.


Assuntos
Luto , Consumo Excessivo de Bebidas Alcoólicas , COVID-19 , Masculino , Humanos , Feminino , Estados Unidos , Georgia/epidemiologia , Prevalência , Estudos Transversais , Consumo Excessivo de Bebidas Alcoólicas/epidemiologia , Pandemias , COVID-19/epidemiologia , Etanol , Consumo de Bebidas Alcoólicas/epidemiologia , Fatores de Risco , Sistema de Vigilância de Fator de Risco Comportamental
5.
J Gerontol B Psychol Sci Soc Sci ; 75(3): 640-649, 2020 02 14.
Artigo em Inglês | MEDLINE | ID: mdl-29635530

RESUMO

OBJECTIVES: We evaluated the association between cumulative stressful life events (SLE) and type of stress (lifetime vs recent) and incident diabetes (Type 2 diabetes mellitus [T2DM]) in middle-aged U.S. adults. METHODS: Data from the 2006-2014 waves of the Health and Retirement Study (HRS) were analyzed (n = 7,956). Stress-related differences in age at T2DM diagnosis were estimated using Cox proportional hazards models. RESULTS: The adjusted risk of T2DM significantly increased by 6% per unit increase in cumulative SLE (95% confidence interval [CI] = 1.03, 1.11), by 5% per unit increase in lifetime stress (95% CI = 1.00, 1.09), and by 23% per unit increase in recent stress (95% CI = 1.12, 1.36). Each level of cumulative SLE (1, 2, 3, and ≥4 events) and recent stress (1 and ≥2 events) compared to no stress was significantly associated with an increased risk of T2DM. Each level of lifetime stress compared to no stress was significantly associated with an elevated risk of T2DM except for 3 events. DISCUSSION: Cumulative SLE and type of stress were associated with incident T2DM in middle-aged adults. Reducing the direct effect of stress with management interventions may reduce the indirect effect of developing T2DM and warrants further investigation.


Assuntos
Diabetes Mellitus Tipo 2/epidemiologia , Estresse Psicológico/epidemiologia , Idoso , Idoso de 80 Anos ou mais , Feminino , Inquéritos Epidemiológicos , Humanos , Incidência , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Modelos de Riscos Proporcionais , Estados Unidos/epidemiologia
6.
Qual Life Res ; 25(4): 1007-15, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-26475139

RESUMO

OBJECTIVE: To test the hypothesis that higher levels of resilience indicators are associated with lower overall healthcare utilization (HCU) as well as improvements in self-rated health (SRH), we analyzed a representative sample of 4562 adults 50-70 years old enrolled in the US 2010 health and retirement survey. METHODS: Multivariable logistic regression models estimated odds ratios (ORs) and 95 % confidence intervals (CIs) for high versus low resilience in relation to HCU and SRH improvements over 2 years. Resilience indicators included: cumulative lifetime adversity, social support, global mastery and domain-specific mastery. Cumulative lifetime adversity was defined as 0, 1-2, 3-4 or 5+ events. HCU included hospitalization (any vs. none) and physician visits (< 20 vs. ≥ 20) over 2 years. FINDINGS: Hospitalization odds declined by 25 % (OR 0.75, 95 %CI 0.64-0.86), odds of ≥ 20 physician visits declined by 47 % (OR 0.53, 95 % CI 0.45-0.63) and the odds of SRH improvement increased by 49 % (OR 1.49, 95 % CI 1.17-1.88) for respondents with high versus low health mastery. Cumulative lifetime adversity manifested a dose-dependent positive relationship with HCU. Specifically, hospitalization odds was, respectively, 25, 80 and 142 % elevated for participants that reported 1-2, 3-4 and 5+ versus 0 lifetime adversities. High versus low global, financial and health mastery, respectively, predicted improved SRH, lower physician's visits and hospitalizations. CONCLUSION: In this sample of adults near or in retirement, resilience predicted lower HCU and improved SRH. Resilience is a dynamic state that can be enhanced in adults with positive impacts on subjective well-being and HCU.


Assuntos
Atenção à Saúde/estatística & dados numéricos , Hospitalização/estatística & dados numéricos , Aceitação pelo Paciente de Cuidados de Saúde/estatística & dados numéricos , Qualidade de Vida/psicologia , Resiliência Psicológica , Aposentadoria/psicologia , Idoso , Feminino , Serviços de Saúde/economia , Humanos , Masculino , Pessoa de Meia-Idade , Apoio Social , Inquéritos e Questionários , Resultado do Tratamento
7.
Am J Hosp Palliat Care ; 33(1): 41-6, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-25258335

RESUMO

In a society of long lives, parent and child life can overlap by as much as 50 years. Most children now experience the death of their parents as adults. Many of the 2.5 million deaths each year in the United States are parents. Parental loss is a risk factor for subsequent illness. The Health and Retirement Survey is a representative cohort of persons aged 50 to 70 years. Using the 2010 cohort data, we estimate risk for use of health care after the death of a parent. Loss is a near universal experience in the cohort (87%). A report of any loss increases risk of health care utilization by 20% to 30%. For a longevity society, preventing loss-related hospitalization is a measurable outcome for bereavement care.


Assuntos
Pesar , Relações Pais-Filho , Pais/psicologia , Aposentadoria , Adaptação Psicológica , Idoso , Idoso de 80 Anos ou mais , Atitude Frente a Morte , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Inquéritos e Questionários , Estados Unidos
8.
J Am Med Dir Assoc ; 16(10): 892-5, 2015 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-26208900

RESUMO

PURPOSE: The purpose of this study was to explore approaches used by administrators to respond to grief and bereavement among staff after the death of a resident. METHODS: Continuing care retirement community (CCRC) facilities (n = 10) were randomly selected from a larger study of 31 facilities. Open-ended interviews were conducted using a structured interview protocol. Qualitative methods, specifically thematic analysis, were used to analyze the interview data. FINDINGS: Emergent themes suggest that LTC facilities have freedom in how to provide support for staff members, family members, and other residents after the death of a loved one. However, results show variations in methods for notifying staff of a resident's death, inclusion of direct care staff in caring for the deceased, providing memorial services, and offering grief/bereavement support. When speaking of the loss of a resident and ways to provide grief/bereavement support, only 3 of the 10 administrators discussed the importance of extending such services to the staff. IMPLICATIONS: Causes of staff burnout in the CCRC workplace is an unresolved issue. Research has shown that inadequate grief and bereavement support for staff contributes to factors associated with staff burnout and retention. Although administrators hold formal services after a resident has died, there are differences among facilities. It may be that organizations could improve bereavement services for staff.


Assuntos
Atitude Frente a Morte , Luto , Recursos Humanos de Enfermagem/psicologia , Apoio Social , Assistentes Sociais/psicologia , Esgotamento Profissional/prevenção & controle , Clero , Habitação para Idosos , Humanos , Enfermeiros Administradores , Estados Unidos
10.
Curr HIV Res ; 13(5): 359-68, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25981706

RESUMO

BACKGROUND: Older adults are remaining sexually active for longer periods of time, underscoring the need to assess sexual activity patterns in this group and identify differences by race/ethnicity, some of which may have implications for the development and implementation of sexual risk reduction interventions. METHODS: Using data from the 2010 National Social Life, Health, and Aging Project, this study examined responses from 1,429 adults aged 60 years and older. Multinomial logistic regression compared sexual behaviors, health-related indicators, interactions with healthcare professionals, and HIV-related perceptions across participants' race/ethnicity. RESULTS: Approximately 81% of participants self-reported as non-Hispanic white, 10.59% as African American, and 8.05% as Hispanic. On average, participants were 69.9 years of age. In the previous year, 49.3% of participants engaged in sexual intercourse; only 3% used condoms. The majority of participants (83.1%) visited a physician at least twice in the previous year, 30.9% had discussed sex with a physician since turning 50, and 14.2% had been tested for HIV. Relative to non-Hispanic whites, African Americans were more likely to be divorced (OR=3.23, P<0.001) or widowed (OR=2.90, P<0.001); have more lifetime sexually transmitted infection (STI) diagnoses (OR=1.67, P=0.030); and have paid for sex (OR=2.83, P=0.002). Although African Americans had greater perceived risk for HIV infection (OR=1.66, P=0.046), they were less likely to have discussed sex with a physician since turning 50 (OR=0.45, P=0.009). CONCLUSION: Contextualized interventions to improve patient-provider communication and proactive screening behaviors in sexually-active and aging African Americans are needed.


Assuntos
População Negra/estatística & dados numéricos , Infecções por HIV , Conhecimentos, Atitudes e Prática em Saúde , Serviços de Saúde/estatística & dados numéricos , Hispânico ou Latino/estatística & dados numéricos , Comportamento Sexual/estatística & dados numéricos , População Branca/estatística & dados numéricos , Idoso , Preservativos/estatística & dados numéricos , Estudos Transversais , Feminino , Infecções por HIV/prevenção & controle , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Comportamento Sexual/etnologia , Fatores Socioeconômicos , Estados Unidos
11.
J Gerontol Nurs ; 39(12): 16-21, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-24219075

RESUMO

Attention to ethical issues is a routine part of medical research. In this article, we propose that health policy development, like research, include a formal review of these issues. Ethical knowledge is a critical component of epistemology and inherent in development of laws and principles of justice. However, we cannot assume that new policies are subject to a formal ethics review. The Belmont Report of 1978 provides a platform for this process. Prior to the Belmont Report, there was no foundation defining this process in medical research. Based on this history, we propose that health care payment policy development include a formal assessment of risks and benefits using an approach that is familiar to all researchers.


Assuntos
Ética , Política de Saúde , Direitos Humanos , Humanos , Qualidade da Assistência à Saúde
12.
J Aging Res ; 2013: 982052, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-24224090

RESUMO

Previous research emphasizes the importance of reducing healthcare frustrations and enhancing physician supports to help patients engage in recommended healthcare regimens. However, less is known about how these factors are associated with aging women's knowledge about self-care behavior. This study examined the sociodemographics, health indicators, healthcare-related frustrations, and perceptions of physician support associated with middle-aged and older adult females' self-reported need for help to learn how to take better care of their health. Data were analyzed from 287 females with one or more chronic conditions who completed The National Council on Aging (NCOA) Chronic Care Survey. A logistic regression model was developed. Women who were non-White (OR = 2.26, P = 0.049) were more likely to need help learning how to better manage their health. Those who had some college education or more (OR = 0.55, P = 0.044) and lower healthcare-related frustrations (OR = 0.44, P = 0.017) and perceived to have more physician support (OR = 0.49, P = 0.033) were less likely to need help learning how to better manage their health. Findings can inform the planning, implementation, assessment, and dissemination of evidence-based self-management programs for middle-aged and older women within and outside of clinical settings.

13.
Am J Public Health ; 102(12): 2330-5, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23078483

RESUMO

OBJECTIVES: We investigated the relationship between the number of times a woman has been pregnant and walking difficulty in later life. METHODS: With data from the Hispanic Established Populations for Epidemiologic Studies of the Elderly, a representative population-based cohort of Mexican Americans aged 65 years and older residing in 5 Southwestern states, we measured walking difficulty using 2 items from the performance-oriented mobility assessments: the timed walk and seated chair rise. RESULTS: We observed significantly higher rates of ambulatory limitation among women with 6 or more pregnancies than among women with 4 or fewer pregnancies: 44.9% and 27.0%, respectively, were unable to perform or performed poorly in the seated chair rise and timed walk. Ordinal logistic regression models show that gravidity predicts level of performance in both mobility tasks and that higher gravidity is associated with worse performance, even after adjustment for both age and chronic disease. CONCLUSIONS: Gravidity is a risk factor for ambulatory limitation in old age. A life course approach to reproduction in public health research and practice is warranted.


Assuntos
Limitação da Mobilidade , Gravidez/estatística & dados numéricos , Idoso , Feminino , Humanos , Modelos Logísticos , Americanos Mexicanos/estatística & dados numéricos , Paridade , Fatores de Risco , Sudoeste dos Estados Unidos/epidemiologia
14.
Gerontologist ; 50(6): 735-43, 2010 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-20494953

RESUMO

Aging of the U.S. population raises numerous public policy issues about which gerontological researchers, policy experts, and practitioners have much to contribute. However, the means by which aging-related public policy is influenced are not always apparent. Drawing on experience working in the U.S. Senate and other settings as Health and Aging Policy Fellows, the authors outline the formal and informal processes by which public policy is shaped in the U.S. Congress. Many who seek to influence public policy do so by telling legislators what they want. A less obvious path to policy influence is for gerontologists to offer their expertise to legislators and their staff. The authors provide specific recommendations for how gerontologists can establish productive and ongoing relationships with key legislative players. The authors also emphasize the importance of collaboration with advocacy groups and with local and state stakeholders to advance aging-related public policy to improve the lives of older Americans.


Assuntos
Envelhecimento , Geriatria , Formulação de Políticas , Política , Política Pública , Idoso , Direitos Civis , Etnicidade , Feminino , Humanos , Manobras Políticas , Masculino , Defesa do Paciente , Médicos , Estados Unidos
15.
Am J Geriatr Pharmacother ; 7(4): 197-203, 2009 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-19766951

RESUMO

BACKGROUND: In patients with atrial fibrillation (AF), anticoagulation with warfarin decreases the risk of embolic stroke by >50%. Identification of genetic polymorphisms in enzymes involved in the metabolism of warfarin can partially predict the maintenance dose and thus potentially decrease the incidence of bleeding episodes secondary to warfarin overdose. OBJECTIVES: The objectives of this study were to evaluate the potential clinical and economic outcomes of genotype-guided warfarin therapy in elderly patients newly diagnosed with AF and to identify a threshold in bleeding risk at which such therapy may be cost-effective. METHODS: A decision tree was designed to represent the medical decision (pharmacogenetic testing or not) and the main clinical outcomes (embolic stroke, bleeding). Event rates of embolic stroke and bleeding complications were based on data from previously published clinical trials and an observational study, respectively; costs were from a third-party payer perspective; and utilities were from the patient perspective. It was assumed that use of pharma-cogenetic testing would not lead the clinician to make any potentially harmful modifications to the regimen. RESULTS: This analysis found that any reduction in major bleeding as a result of pharmacogenetic testing would lead to improved utility. The higher costs of pharmacogenetic testing compared with no testing would be immediately offset by any reduction in major bleeding. CONCLUSIONS: In this decision analysis, genotype-guided warfarin therapy for anticoagulation in elderly patients with AF was potentially cost-effective, and its benefits were closely related to efficacy in preventing bleeding events. Clinical trials testing the efficacy of genotype-guided warfarin therapy are warranted.


Assuntos
Anticoagulantes/economia , Anticoagulantes/uso terapêutico , Fibrilação Atrial/tratamento farmacológico , Fibrilação Atrial/genética , Genótipo , Varfarina/economia , Varfarina/uso terapêutico , Idoso , Anticoagulantes/efeitos adversos , Fibrilação Atrial/economia , Análise Custo-Benefício , Hemorragia/induzido quimicamente , Hemorragia/economia , Hemorragia/epidemiologia , Humanos , Coeficiente Internacional Normatizado , Embolia Intracraniana/economia , Embolia Intracraniana/epidemiologia , Embolia Intracraniana/prevenção & controle , Farmacogenética , Medição de Risco , Acidente Vascular Cerebral/economia , Acidente Vascular Cerebral/epidemiologia , Acidente Vascular Cerebral/prevenção & controle , Resultado do Tratamento , Varfarina/efeitos adversos
16.
J Ky Med Assoc ; 105(9): 439-43, 2007 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-17941422

RESUMO

This has been a commentary on the implications of policy changes for nursing homes and rehabilitation hospital admissions. Only time will show how greatly this will affect the nursing home. However, since the 2004 implementation of the 75% Rule, nursing homes have already seen a jump in patients who are more acutely ill and have multiple medical needs. To lessen the potential burden of these changes on patient safety and comfort and to increase family satisfaction with care, we propose the following steps be considered. 1. We need better integration between hospital and nursing homes. Indeed, a strategic alliance between hospitals and nursing homes would be something that we should consider sooner rather than later. 2. All providers should understand that this is a continued push by both private and government insurance to get the patient out of the hospital sooner. As a result, patients will be discharged either to the rehab hospital or to the nursing home "sicker and quicker." 3. The implementation of the 75% Rule will probably result in a decreased use of rehab hospitals and an increased use of the nursing home. 4. In looking even further into the future, the nursing homes themselves are likely to be under continued pressure to get patients out of the nursing home more quickly. This in turn will result in what we consider the next big thing-home care.


Assuntos
Assistência ao Convalescente/organização & administração , Casas de Saúde/organização & administração , Alta do Paciente/normas , Transferência de Pacientes/normas , Sistema de Pagamento Prospectivo/legislação & jurisprudência , Centros de Reabilitação/organização & administração , Assistência ao Convalescente/economia , Assistência ao Convalescente/estatística & dados numéricos , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Relações Interinstitucionais , Kentucky , Masculino , Medicaid/legislação & jurisprudência , Medicare/legislação & jurisprudência , Pessoa de Meia-Idade , Casas de Saúde/economia , Casas de Saúde/estatística & dados numéricos , Dinâmica Populacional , Centros de Reabilitação/economia , Centros de Reabilitação/estatística & dados numéricos , Contrato de Transferência de Pacientes , Estados Unidos
18.
J Ky Med Assoc ; 104(11): 519-22, 2006 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-17175854

RESUMO

OBJECTIVE: To measure whether the addition of a BMI chart to a patient's medical record at the time of the office visit would increase the likelihood of a physician discussing weight management with the patient. METHODS: Office staff were instructed to place a BMI chart on the front of medical charts of all patients aged 21 years to 65 years who were seen during a 2-month period in two urban university-affiliated clinics. The staff were to plot the BMI on the chart. The medical records were audited for the presence of the BMI chart and any documentation of a discussion of weight management. RESULTS: Of the 961 charts that were audited, 44% contained the BMI chart. A discussion of weight management issues was documented in 19% of those that contained a BMI chart and in 15% of those that did not contain a BMI chart. CONCLUSIONS: Data presented here suggest that adding a BMI chart to the patient medical record may increase the attention of a physician to weight management issues.


Assuntos
Índice de Massa Corporal , Prontuários Médicos , Atenção Primária à Saúde/organização & administração , Adulto , Idoso , Peso Corporal/fisiologia , Feminino , Humanos , Kentucky , Masculino , Auditoria Médica , Pessoa de Meia-Idade
19.
J Gerontol A Biol Sci Med Sci ; 61(2): 170-5, 2006 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-16510861

RESUMO

BACKGROUND: Numerous methods have been used to evaluate medication management quality in older adults; however, their predictive validities are unknown. Major medication quality indicators include polypharmacy, drug-drug interactions, and inappropriate medication use. To date, no study has attempted to evaluate the three approaches systematically or the effect of each approach on mortality in a Hispanic population. Our objective was to evaluate the relationship between polypharmacy, drug-drug interactions, and inappropriate medication use on the mortality of a community-based population of Mexican American older adults. METHODS: We used a life table survival analysis of a longitudinal survey of a representative sample of 3,050 older Mexican Americans of whom 1,823 were taking prescription and over-the-counter medications. RESULTS: After adjustment for relevant covariates, use of more than four different medications (polypharmacy) was independently associated with mortality. The presence of major drug interactions and the use of inappropriate medications were not significantly associated with mortality in our study sample. CONCLUSION: Polypharmacy (>4 medications) is significantly associated with mortality in Mexican American older adults. This community-based study is the first to demonstrate a direct association between polypharmacy and mortality in this population.


Assuntos
Tratamento Farmacológico/estatística & dados numéricos , Americanos Mexicanos , Mortalidade , Idoso , Idoso de 80 Anos ou mais , Estudos de Coortes , Feminino , Humanos , Estudos Longitudinais , Masculino , Polimedicação
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