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1.
Int J Surg Case Rep ; 110: 108665, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-37634438

RESUMO

INTRODUCTION AND SIGNIFICANCE: Foreign body ingestion is a frequent and potentially life-threatening concern in children, with button batteries being the second most frequently ingested object trailing coins. The mechanical and chemical impact of foreign objects on delicate esophageal lumen poses a grave concern. CASE PRESENTATION: Herein, we unveil a compelling case of a two-year-old girl who suffered from difficulty in swallowing, weight loss, and frequent chest infections. A chest X-ray revealed a halo sign within the confines of her thoracic esophagus. However, the formidable challenge of extensive inflammation greatly hindered visibility during esophagoscopy, leading to an imperative decision of thoracotomy. The surgical exploration uncovered an esophageal diverticulum, skillfully managed with a conservative approach. Three months postoperatively, she resumed regular feeds without chest symptoms. DISCUSSION: Foreign body ingestion is predominantly among children below four years, with button batteries being among the frequent objects involved. Endoscopic retrieval is an effective and less morbid procedure for foreign body retrieval. Esophageal diverticula following button battery ingestion have rarely been reported. CONCLUSION: Timely diagnosis and effective management of esophageal foreign bodies are crucial, as chemical reactions from button batteries can commence within two hours of ingestion. Swift and decisive actions, coupled with less morbid procedures such as endoscopic retrieval should be prioritized in the management.

2.
Parasit Vectors ; 15(1): 396, 2022 Oct 28.
Artigo em Inglês | MEDLINE | ID: mdl-36307877

RESUMO

BACKGROUND: There are close similarities between the life-cycles of Echinococcus granulosus sensu lato (E. granulosus s.l.) that causes cystic echinococcosis (CE) in humans and Taenia multiceps/Coenurus cerebralis that causes cerebral coenurosis in small ruminants. Recent evidence highlights that livestock in Maasai communities of northern Tanzania are suffering from increases in the prevalence of cerebral coenurosis, leading to concerns about a possible concurrent increased risk of human CE. The aim of this study was to estimate the prevalence of human abdominal CE and the prevalence and species/genotypes of E. granulosus s.l. in livestock in Maasai communities. METHODS: Human CE was diagnosed by abdominal ultrasound on volunteers aged ≥ 7 years in five villages in the Longido and Ngorongoro Districts in northern Tanzania. Infection in ruminants was evaluated through inspection in local abattoirs, followed by molecular identification of one cyst per animal, with a priority for hepatic cysts, using PCR targeting of the cytochrome c oxidase I gene (COX1), followed by restriction fragment length polymorphism and multiplex PCR, and sequencing of non-E. granulosus s.l. samples. RESULTS: Ultrasound was performed on 823 volunteers (n = 352 in two villages in Longido District, and n = 471 in three villages of Ngorongoro). Hepatic CE cases were diagnosed only in Ngorongoro (n = 6; 1.3%), of which three had active cysts. Village-level prevalence of CE ranged between 0 and 2.4%. Of the 697 ruminants inspected, 34.4% had parasitic cysts. Molecular identification was achieved for 140 of the 219 (63.9%) cysts sampled. E. granulosus s.l. and T. hydatigena/Cysticercus tenuicollis were identified in 51.4% and 48.6%, respectively, of livestock cysts. E. granulosus s.l. was identified in livestock from both Longido (35.3% of 116 genotyped cysts) and Ngorongoro (91.2% of 34 genotyped cysts). Of the total of 72 E. granuslosus s.l. cysts identified in livestock, 87.5% were E. granulosus sensu stricto (G1-G3 genotypes), 9.7% were E. ortleppi (G5) and one cyst was E. canadensis (G6-10). The three active human cysts, which were removed surgically, were G1-G3 genotypes. CONCLUSIONS: Multiple species/genotypes of E. granulosus s.l. are circulating in Maasai communities of northern Tanzania. Human CE was detected in villages of Ngorongoro District and a high prevalence of echinococcal cysts was observed in livestock in both districts. More precise estimation of the prevalence in this area and a better understanding of the specific risk factors for CE among Maasai communities in northern Tanzania is needed. Interventions targeting transmission routes common to both E. granulosus s.l. and T. multiceps would have dual benefits for preventing both human and livestock disease.


Assuntos
Cistos , Equinococose , Echinococcus granulosus , Neurocisticercose , Animais , Humanos , Gado/parasitologia , Projetos Piloto , Tanzânia/epidemiologia , Equinococose/epidemiologia , Equinococose/veterinária , Equinococose/parasitologia , Echinococcus granulosus/genética , Genótipo
3.
Int J Surg Case Rep ; 98: 107529, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-36027829

RESUMO

INTRODUCTION: Porocarcinoma is a rare malignancy of dermal sweat glands commonly diagnosed in the seventh decade of life. It frequently evolves from a de novo benign poroma. These tumors present as a mass/nodule, ulcer, papule, or wart. Difficult to differentiate from other cutaneous lesions. Intraperitoneal invasion is scantly reported in the literature. CASE PRESENTATION: The authors present a case of a fifty-year-old female patient with a rare cancer of the dermal sweat glands in an unusual location and infiltration into the abdominal cavity, leading to intraperitoneal seedlings. DISCUSSION: Tumors of the sweat gland are rare and difficult to diagnose, often misdiagnosed as granuloma, squamous cell tumors, or warts. Surgical excision and Mohs micrographic surgery are mainstay treatment modalities in the early stages. Our patient was managed elsewhere with a diagnosis of granuloma. She was referred with a recurrence of the abdominal lesion. An appropriate diagnosis of porocarcinoma was made while she had an extensive intraperitoneal invasion and seedlings. We postulate that the previous abdominal incision had disseminated porocarcinoma cells into the abdominal cavity, causing extensive intraperitoneal dissemination. CONCLUSION: Because it is rare and difficult to diagnose, there is a considerable knowledge gap in the early accurate diagnosis and appropriate management of porocarcinoma. This causes a delay in establishing a diagnosis and profoundly impacts treatment outcomes.

4.
Int J Surg Case Rep ; 98: 107486, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-35964371

RESUMO

INTRODUCTION: Penetrating injuries to the upper aerodigestive tract are potentially life-threatening, with significant morbidity and mortality. Although rare, the cervical esophagus is the most vulnerable part of the esophagus to penetrating injuries. Given the unique and condensed anatomy of the neck, penetrating injuries to the second zone of the neck pose a demanding challenge. Contention exists in diagnosing and managing penetrating esophageal injuries. CASE PRESENTATION: Herein is a case of a young male with a penetrating neck injury from the left lateral aspect with subsequent esophageal injury. An early primary repair with muscle buttress resulted in admirable results. DISCUSSION: Accurate diagnosis and timely management are critical in deflating morbidity and mortality. Flexible esophagoscopy and Computed tomography with water-soluble contrast are the ideal modalities for diagnosing penetrating neck injuries, as clinical evaluation alone can readily overlook cervical esophagus injury. The esophageal repair depends on the patient's clinical condition, the extent of damage, anatomical location, and duration of the injury. Management varies from a conservative approach to radical esophagectomies. Surgery remains a cornerstone in managing penetrating esophageal injuries. Primary repair with an external drain is advocated within 24 h of injury. CONCLUSION: A high index of suspicion and timely diagnosis are critical in successfully managing penetrating esophageal injuries. Neck injuries demand a comprehensive evaluation for any aerodigestive or vascular leaks. Early primary repair with a muscle buttress improves the chance of an effective repair.

5.
Int J Surg Case Rep ; 97: 107406, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-35839653

RESUMO

INTRODUCTION: Chylous ascites is the collection of milky-like fluid rich in triglycerides within the peritoneal cavity. It results from disruption of normal intestinal lymphatic flow. It is caused mainly by congenital anomalies, trauma, and malignancy. Chylous ascites following blunt abdominal injury is uncommon in pediatrics. Chyle duct and pancreatic injuries present a rare clinical sequela yet to be reported in the literature. Conservative management is the mainstay of treating chyle duct injuries, reserving invasive measures for unique circumstances. CASE PRESENTATION: A case of an eleven-year-old female who suffered blunt thoracoabdominal trauma and sustained injuries to the chest, pancreas, and chyle duct. She had clinical signs of peritonism and decreased air entry on the right hemithorax. While she underwent abdominal exploration, the chylous ascites eventually resolved on conservative management, and the pancreatic pseudocyst was later drained percutaneously. DISCUSSION: Chylous ascites and pancreatic pseudocyst is uncommon in pediatrics. While surgery is indicated in selected cases, a conservative approach is advocated in managing lymphatic leaks. Diet with low triglycerides and high protein is advocated to decrease lymph production. Treatment of pancreatic pseudocyst varies from conservative (watchful waiting) to drainage measures. CONCLUSION: Although chylous ascites is not expected following trauma, has to be considered among differential free peritoneal fluid. Pancreatic injuries are common but difficult to diagnose. CT and MRCP are preferred modalities for diagnosing pancreatic injuries. While dietary modification and drainage of the chylous ascites were the mainstays in managing chyle duct injury, pancreatic pseudocyst resolved after percutaneous drainage.

6.
J Surg Case Rep ; 2022(1): rjab645, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-35096373

RESUMO

We report a case of a two month old baby who had presented with an acute abdomen. Intra operative necrosis of the abdominal esophagus to distal of ligamentum treitz was noted. He was subjected to palliative care and passed away on Day 8 post-surgery.

7.
J Surg Case Rep ; 2022(1): rjab600, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-35047180

RESUMO

Bilateral chylothorax is a rare complication following neck dissection, with fewer than thirty cases being reported over the last century. A serious life-threatening condition mostly encountered during thoracic procedures and dissections. In our case, conservative management resulted in complete resolution. We report a case of a 4-year-old child who underwent deep neck dissection due to recurrent hemangioma. She developed bilateral chylothorax and a conservative approach led to complete resolution.

8.
JCO Glob Oncol ; 6: 375-381, 2020 03.
Artigo em Inglês | MEDLINE | ID: mdl-32125898

RESUMO

PURPOSE: A trend of increasing incidence of colorectal cancer (CRC) has been observed in northern Tanzania. Studies have shown a six-fold increase in CRC in the past decade, with 90% of patients presenting in late stages, with resultant high morbidity and mortality rates. In this study, we aimed to document the burden of CRC in the northern zone of Tanzania from 1998 to 2018, focusing on patient presentation, clinical features, and treatment at a tertiary hospital. METHODS: Pathological and clinical records for all patients from 1998 to 2018 were identified and reviewed. Records of patients whose CRC was diagnosed histologically were retrospectively reviewed. RESULTS: Approximately 313 CRC cases were documented. The majority age group (29.1%) was between 50 and 64 years (mean [standard deviation], 54.28 [16.75] years). However, together, the age groups of patients younger than 50 years was 41.5% (n = 130). Of 174 patients with complete records, most (29.3%) were between 35 and 49 years of age. The median age was 52 (interquartile range, 40-67) years. Men accounted for 62.1% of patients and were mostly from the Kilimanjaro region. More than half (54.7%) presented > 3 months after symptom debut; 62.6% first sought care at lower-level health facilities. Most (64.9%) presented as emergencies, necessitating colostomy for fecal diversion as the initial surgical procedure in 60.3% of patients. Colonoscopy was performed for 38.6% of the study participants. Most tumors (72.7%) originated from the sigmoid and rectum. Adenocarcinoma was the most prevalent histologic type. CONCLUSION: High proportions of young individuals with CRC pose great concern and a need for further appraisal. Furthermore, late emergency presentation and low colonoscopy rates highlights underlying system challenges and need for education campaigns.


Assuntos
Neoplasias Colorretais , Detecção Precoce de Câncer , Adulto , Colonoscopia , Neoplasias Colorretais/diagnóstico , Neoplasias Colorretais/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Tanzânia/epidemiologia
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