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Intern Med ; 62(16): 2419-2425, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37587059

RESUMO

We herein report a rare case of distal chronic inflammatory demyelinating polyneuropathy (CIDP) following coronavirus disease 2019 (COVID-19) vaccination. A 39-year-old woman with a solitary plasmacytoma developed general weakness 7 days after receiving the second dose of the Pfizer-BioNTech COVID-19 vaccine, which had progressed for 3 months. A neurological examination revealed limb weakness with areflexia. Serological tests identified the presence of IgG antibodies against anti-GM1 and anti-GM2 gangliosides. Comprehensive evaluations met the criteria of distal CIDP. Intravenous immunoglobulin, intravenous methylprednisolone, oral prednisolone, and plasma exchange were administered, and she gradually improved. Physicians should be aware of CIDP as a rare complication of COVID-19 vaccination.


Assuntos
Vacina BNT162 , Neoplasias Ósseas , COVID-19 , Plasmocitoma , Polirradiculoneuropatia Desmielinizante Inflamatória Crônica , Adulto , Feminino , Humanos , Vacina BNT162/efeitos adversos , COVID-19/prevenção & controle , Plasmocitoma/diagnóstico , Polirradiculoneuropatia Desmielinizante Inflamatória Crônica/diagnóstico , Polirradiculoneuropatia Desmielinizante Inflamatória Crônica/tratamento farmacológico , Polirradiculoneuropatia Desmielinizante Inflamatória Crônica/etiologia
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