RESUMO
Purpose: The purpose of this study is to construct a synthetic dataset of ECG signal that overcomes the sensitivity of personal information and the complexity of disclosure policies. Methods: The public dataset was constructed by generating synthetic data based on the deep learning model using a convolution neural network (CNN) and bi-directional long short-term memory (Bi-LSTM), and the effectiveness of the dataset was verified by developing classification models for ECG diagnoses. Results: The synthetic 12-lead ECG dataset generated consists of a total of 6000 ECGs, with normal and 5 abnormal groups. The synthetic ECG signal has a waveform pattern similar to the original ECG signal, the average RMSE between the two signals is 0.042 µV, and the average cosine similarity is 0.993. In addition, five classification models were developed to verify the effect of the synthetic dataset and showed performance similar to that of the model made with the actual dataset. In particular, even when the real dataset was applied as a test set to the classification model trained with the synthetic dataset, the classification performance of all models showed high accuracy (average accuracy 93.41%). Conclusion: The synthetic 12-lead ECG dataset was confirmed to perform similarly to the real-world 12-lead ECG in the classification model. This implies that a synthetic dataset can perform similarly to a real dataset in clinical research using AI. The synthetic dataset generation process in this study provides a way to overcome the medical data disclosure challenges constrained by privacy rights, a way to encourage open data policies, and contribute significantly to promoting cardiovascular disease research.
RESUMO
Whole-body center of gravity (CG) movements in relation to the center of pressure (COP) offer insights into the balance control strategies of the human body. Existing CG measurement methods using expensive measurement equipment fixed in a laboratory environment are not intended for continuous monitoring. The development of wireless sensing technology makes it possible to expand the measurement in daily life. The insole system is a wearable device that can evaluate human balance ability by measuring pressure distribution on the ground. In this study, a novel protocol (data preparation and model training) for estimating the 3-axis CG trajectory from vertical plantar pressures was proposed and its performance was evaluated. Input and target data were obtained through gait experiments conducted on 15 adult and 15 elderly males using a self-made insole prototype and optical motion capture system. One gait cycle was divided into four semantic phases. Features specified for each phase were extracted and the CG trajectory was predicted using a bi-directional long short-term memory (Bi-LSTM) network. The performance of the proposed CG prediction model was evaluated by a comparative study with four prediction models having no gait phase segmentation. The CG trajectory calculated with the optoelectronic system was used as a golden standard. The relative root mean square error of the proposed model on the 3-axis of anterior/posterior, medial/lateral, and proximal/distal showed the best prediction performance, with 2.12%, 12.97%, and 12.47%. Biomechanical analysis of two healthy male groups was conducted. A statistically significant difference between CG trajectories of the two groups was shown in the proposed model. Large CG sway of the medial/lateral axis trajectory and CG fall of the proximal/distal axis trajectory is shown in the old group. The protocol proposed in this study is a basic step to have gait analysis in daily life. It is expected to be utilized as a key element for clinical applications.
