RESUMO
Four thymol derivatives and two phenolic compounds were isolated from the aerial parts of Eupatorium fortunei. The new structures were elucidated to be 7,8,9-trihydroxythymol (1), and 8,10-didehydro-7,9-dihydroxythymol (2) by means of MS and NMR analysis. The known compounds were identified as 8,9,10-trihydroxythymol (3), 10-acetoxy-8,9-dihydroxythymol (4), o-coumaric acid (5) and 4-(2-hydroxyethyl)benzaldehyde (6). Compound 3 showed strongest inhibitory effect on the growth of Microcystis aeruginosa in comparison with CuSO4.
Assuntos
Antibacterianos/farmacologia , Eupatorium/química , Fenóis/química , Antibacterianos/química , Avaliação Pré-Clínica de Medicamentos , Espectroscopia de Ressonância Magnética , Microcystis/efeitos dos fármacos , Estrutura Molecular , Fenóis/farmacologia , Componentes Aéreos da Planta/química , Extratos Vegetais/química , Timol/química , Timol/farmacologiaRESUMO
A new alkaloid, isostenine (1), together with two known ones neotuberostemonine (2) and bisdehydroneotuberostemonine (3) were isolated from the root of Stemona collinsae. Their structures were determined by various spectral methods.
