Correlation between oral muscle pressure and malocclusion in mixed dentition: a cross-sectional study.

OBJECTIVE: To investigate the relationship between oral muscle pressure and malocclusion in the mixed dentition. MATERIALS AND METHODS: Maximum tongue, lip and cheek pressure was measured using the Iowa Oral Performance Instrument (IOPI) in 3 patient cohorts: patients with (1) posterior crossbite, (2) class II relationship and (3) a control group of patients without malocclusion. Linear models were used to compare the mean differences in muscle pressure between groups, with correction for age and gender. The imbalance between lips and tongue and between lips and cheeks was calculated by the Delta z-scores of each group. RESULTS: A total of 146 participants were included, 46 (mean age 8.71±0.85), 41 (mean age 11.74±1.17) and 35 (mean age 10.71±1.92) in groups 1, 2 and 3 respectively. Patients with malocclusion showed significantly higher lip and lower cheek pressure and imbalance favouring the lips over the tongue compared to controls. Class II,1 patients showed significantly higher tongue pressure than Class II,2. No differences were found in muscle pressure or imbalance between crossbite and Class II nor between crossbite types. CONCLUSION AND CLINICAL RELEVANCE: These findings suggest that oral muscle pressure may be associated with malocclusion. This highlights the importance of functional diagnosis and its implications on the prevention and treatment of malocclusion, as well as on orthodontic stability.

Risk factors for orthodontic fixed retention failure: A retrospective controlled study.

Objective: : To investigate the potential correlation between fixed orthodontic retention failure and several patient- and treatment-related factors. Methods: : Patients finishing treatment with fixed appliances between 2016 and 2017 were retrospectively included in this study. Those not showing fixed retention failure were considered as control group. Patients with fixed retention failure were considered as the experimental group. Additionally, patients with failure of fixed retainers in the period of June 2019 to March 2021 were prospectively identified and included in the experimental group. The location of the first retention failure, sex, pretreatment dental occlusion, facial characteristics, posttreatment dental occlusion, treatment approach and presence of oral habits were compared between groups before and after treatment separately by using a Fisher exact test and a Mann-Whitney U test. Results: : 206 patients with fixed retention failure were included, 169 in the mandibular and 74 in the maxillary jaws. Significant correlations were observed between retention failure in the mandibular jaws and mandibular arch length discrepancy (P = 0.010), post-treatment growth pattern (P = 0.041), nail biting (P < 0.001) and abnormal tongue function (P = 0.002). Retention failure in the maxillary jaws was more frequent in patients with IPR in the mandibular jaws (P = 0.005) and abnormal tongue function (P = 0.021). Conclusions: : This study suggests a correlation between fixed retention failure and parafunctional habits, such as nail biting and abnormal tongue function. Prospective studies with larger study populations could further confirm these results.

Influence of age and diet consistency on the oral muscle pressure of orthodontically treated and untreated subjects with normal occlusion and comparison of their 3D facial shape.

OBJECTIVES: (1) To investigate the effect of age and diet consistency on maximum lips, tongue and cheek pressure of orthodontically treated and untreated subjects with normal, Class I dental occlusion, (2) to find out whether there is a muscle imbalance between anterior tongue and lip pressure in the same subjects at different ages and (3) to compare the 3D facial shape of treated and untreated individuals. MATERIAL AND METHODS: Subjects with normal occlusion were prospectively grouped into orthodontically treated/untreated and in children/adolescents/adults. Iowa Oral Performance Instrument was used to record the maximum muscle pressure. Two-way ANOVA and Tukey post hoc test analysed age-specific differences in muscle pressure. Two-way ANCOVA analysed the effect of diet consistency on muscle pressure. Lips and tongue imbalance was analysed using z-scores and 3D faces using a generalized Procrustes analysis. RESULTS: One hundred thirty-five orthodontically untreated and 114 treated participants were included. Muscle pressure was found to increase with age in both groups, except for the tongue in treated subjects. No differences in the balance between lips and tongue muscle pressure were found, but a higher cheek pressure in untreated adults (p<0.05) was observed. 3D facial shapes showed subtle differences. Untreated subjects with soft diet consistency showed lower lip pressure (p<0.05). CONCLUSION: Oral muscle pressure of orthodontically treated patients without relapse does not differ from that of untreated patients with Class-I occlusion. CLINICAL RELEVANCE: This study provides normative lip, tongue and cheek muscle pressure in subjects with normal occlusion, which can be used for diagnosis, treatment planning and stability.

Skeletal and soft-tissue changes in humans with untreated normal occlusion throughout lifetime: a systematic review.

Age-related skeletal and soft-tissue changes are important in orthodontics, especially due to the increase of adult patients seeking treatment. The aim of this study is to assess the available evidence regarding age-related skeletal and soft-tissue changes in untreated Angle Class I. Articles studying skeletal and soft-tissue changes in orthodontically untreated subjects with Angle Class I and comparing them between age groups were included. Studies focusing on a single age group or in languages other than English were excluded. Risk of bias was assessed with both the MINORS and ROBINS-I tools. 50 studies were included, showing high methodological heterogeneity and a lack of information in subjects over 60 years old. In subjects with Angle Class I, the mandibular plane inclination was reported to reduce from 7 and 20 years old, while the anterior and posterior facial height continue to increase in late adult life. The anterior cranial base length increases until 20 years old, afterwards decreasing slowly until late adulthood. Nasal width increases and the nasolabial angle decreases during adolescence. Upper lip length and lower lip length increase from 6 to 18 years along with retrusion of the lips in late adulthood. Age-related skeletal and soft-tissue changes are documented in the literature from childhood until the fifth decade of life, but studies mostly focus on subjects until 20 years old. Changes after the second decade of life are studied only for the vertical and sagittal dimensions. No changes are reported in the transversal dimension beyond 15 years for neither skeletal nor soft tissues. Well-designed, long-term prospective cohort studies considering all three dimensions of skeletal and soft tissues are needed for confirmation of these findings (PROSPERO: CRD42020203206).

Age- and sex-related differences in 3D facial shape and muscle pressure in subjects with normal occlusion.

BACKGROUND AND OBJECTIVE(S): (1) To derive descriptive statistics of three-dimensional (3D) facial shape, lip and cheek muscle pressure in subjects of European descent with normal dental occlusion. (2) To analyse the effect of age and sex on 3D-facial soft tissue morphology and muscle pressure in the same sample. (3) To assess the independent effect of muscle pressure on face shape. METHOD: 129 subjects with normal occlusion were cross-sectionally recruited and divided into: children (mixed dentition), adolescents and adults (permanent dentition, < and ≥18 years respectively). Muscle pressure was recorded using the Iowa Oral Performance Instrument. MeshLab, MeVisLab and Meshmonk tool box were used to clean, annotate landmarks and generate the 3D images. Two-way analysis of variance and post-hoc tests were used to analyse age and sex differences in face shape and muscle pressure. The effect of muscle pressure on face shape was analysed by Pearson correlation and Partial Least Square regression. RESULTS: Significant facial differences were observed between adults and adolescents and adults and children in both sexes, showing flattening of cheeks and lips and protrusion of nose and chin. Significant cheek protrusion and retrusion of the vertical midface were found in adult women compared to men. Lip and cheek pressure increased with age, but their effect on face shape was not significant. CONCLUSIONS: This study provides 3D age- and sex-specific facial models and muscle pressure of subjects without malocclusion. These can be used as a reference for clinicians focused on facial assessment in treatment planning and follow-up.

Dental changes in humans with untreated normal occlusion throughout lifetime: A systematic scoping review.

INTRODUCTION: Understanding age-related changes in normal dental occlusion is crucial for orthodontic treatment, planning, and retention, especially considering the increasing demand from adult patients. This review aimed to systematically perform a scoping literature review regarding age-related dental changes in untreated normal occlusion subjects. METHODS: An electronic search was performed until May 2020 using the following terms: "Dental Occlusion," "Dentition," "Ageing," and "Age groups." Articles studying changes in dental occlusal traits in orthodontically untreated subjects with neutroclusion and comparing them between various age groups were included. Studies focusing on a single age group or written in languages other than English were excluded. The risk of bias of the studies was assessed with both the methodological index for nonrandomized studies and the risk of bias in nonrandomized studies of intervention tools. RESULTS: From the initial 7681 articles, 40 were included. High methodologic heterogeneity was found among studies. Intercanine width was found to increase until 8.0 years and 15.0 years in the mandible and maxilla, respectively, whereas intermolar width increases in both arches until 26.0 years. After that, both parameters decrease into late adulthood. Crowding increases from mixed dentition until 60.0 years of age, especially in the mandible and females. Maxillary incisors procline with age while mandibular incisors retroclined. CONCLUSIONS: The age-related evolution of occlusal traits, together with skeletal and soft tissue changes, should be considered during orthodontic planning. Well-designed prospective cohort studies are necessary for confirmatory evidence. Expectations for treatment stability should consider muscular balance and inform patients that crowding is a sign of aging that should not always be seen as a failure of orthodontic therapy. Protocol registration number: PROSPERO CRD42020138846.