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1.
Med Leg J ; : 258172241245556, 2024 Jul 29.
Artigo em Inglês | MEDLINE | ID: mdl-39075866

RESUMO

In cases of traumatic deaths, accurate assessment of injuries is essential for both legal and medical purposes. This case report compares the findings of post-mortem computed tomography with conventional autopsy methods in assessing abdominal stab wounds. A 34-year-old woman with multiple stab wounds in the abdomen underwent post-mortem examination, including computed tomography imaging. Computed tomography revealed specific breaches in the skin's continuity and internal injuries, including perforation of the stomach. A conventional autopsy confirmed the presence of multiple stab wounds and associated injuries to internal structures. However, additional injuries to major blood vessels, such as the abdominal aorta and inferior vena cava, were only detected during manual exploration of the peritoneal cavity. This case highlights the complementary roles of post-mortem computed tomography and conventional autopsy in evaluating traumatic injuries. While computed tomography imaging offers non-invasive visualisation of injuries, manual examination remains essential for identifying certain injuries, particularly those affecting major blood vessels. The integration of computed tomography imaging with traditional autopsy methods enhances the accuracy and reliability of forensic assessments in cases of traumatic deaths, particularly in complex cases involving multiple injuries. Understanding the strengths and limitations of these techniques is crucial for improving forensic investigations and ultimately enhancing medico-legal outcomes.

2.
Int J Biol Macromol ; 74: 620-6, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25561048

RESUMO

Chitosan, a natural biopolymer, obtained by alkaline deacetylation of chitin, exhibits excellent biological properties such as biodegradability, immunological and antibacterial activity. Recently, there has been a growing interest in the chemical modification of chitosan in order to widen its applications. The chemical modification of chitosan has been achieved via grafting of monomer, 2-hydroxyethyl methacrylate (HEMA) in the presence of the initiator, ammonium persulfate (APS) and kaolin was added to improve the mechanical strength of the newly developed nanocomposites hydrogel. The so prepared grafted nanocomposites hydrogel was characterized by FTIR, XRD, SEM, TEM and TGA. The equilibrium water content (EWC) of the samples were measured at different pH ranges 6.5-8.0 and found optimum at pH 7.5 for biomedical applications. Further, the biodegradability of the samples was studied at different time intervals from 15 days to 1 year but, the kaolin based nanohydrogels exhibited good biodegradability.


Assuntos
Quitosana/química , Hidrogel de Polietilenoglicol-Dimetacrilato/química , Caulim/administração & dosagem , Nanocompostos/química , Poli-Hidroxietil Metacrilato/química , Materiais Biocompatíveis/química , Sistemas de Liberação de Medicamentos , Teste de Materiais , Estrutura Molecular , Nanocompostos/ultraestrutura , Espectroscopia de Infravermelho com Transformada de Fourier , Termogravimetria , Difração de Raios X
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