1.
Vet Pathol
; 28(4): 338-40, 1991 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-1659021
Assuntos
Doenças do Cão/microbiologia , Infecções por Herpesviridae/veterinária , Herpesviridae/isolamento & purificação , Animais , Anticorpos Antivirais/sangue , Doenças do Cão/patologia , Cães , Herpesviridae/imunologia , Herpesviridae/fisiologia , Infecções por Herpesviridae/microbiologia , Infecções por Herpesviridae/patologia , Masculino , Testes de Neutralização , Pâncreas/patologia , Baço/microbiologia , Timo/microbiologia
2.
Am J Vet Res
; 49(3): 428-31, 1988 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-3358555
RESUMO
The genetic aspects of inherited, insulin-dependent diabetes mellitus of Keeshond dogs were studied retrospectively and in a prospective mating program. The symbol dm was used to designate the gene that causes hypoplasia of the islets of Langerhans. The retrospective study disclosed 4 diabetic dogs; prospective outcross, backcross, and inbred matings disclosed 49 diabetic dogs. Outcrossing demonstrated that the diabetic phenotype was displayed readily against a genetic background of a breed other than the Keeshond. In dogs with the dm/dm genotype, onset of diabetes was most frequent before the dog was 6 months old, but did occur in some older dogs. The dm genotype was best described as autosomal recessive.