The auditory stimulus facilitates memory guidance in distractor suppression in males with substance use disorder.

Introduction: Representations in working memory can affect distractor suppression in human visual search, and this process is modulated by a separate top-down cognitive control. An increasing body of research has demonstrated that patients with substance use disorder (SUD) have deficits in cognitive control over filtering interference by perceptual distractors. However, their ability to resist proactive interference from working memory has received comparatively less attention. Methods: Here, we investigate this issue by employing a working memory/visual search dual-task paradigm. An intervening gap-location search task was instructed to be performed while participants memorized a written color word, with congruent auditory information present during the memory encoding phase on half of the trials. Results: Results showed that there was a reliable response time (RT) advantage when the meaning of the memory sample agreed with the color of one of the distractors under the visual alone condition. However, such a result was only found in the control group. More importantly, both groups exhibited comparable facilitation under the audiovisual condition, with the facilitation effect appearing later in the SUD group. Furthermore, the facilitation effect was superior in magnitude and time course under the audiovisual condition to the visual alone condition. Discussion: These findings highlight how patients with SUD resist distractor interference at the memory level and extend our understanding of how working memory, selective attention, and audiovisual enhancement interact to optimize perceptual decisions in patients with SUD.

Differential effects of high-definition transcranial direct current stimulation (HD-tDCS) on attentional guidance by working memory in males with substance use disorder according to memory modality.

Information stored in working memory can guide perception selection, and this process is modulated by cognitive control. Although previous studies have demonstrated that neurostimulation over the left dorsolateral prefrontal cortex (lDLPFC) contributes to restore cognitive control among individuals with substance use disorder (SUD), there remains an open question about the potential stimulation effects on memory-driven attention. To address this issue, the present study adopted a combined working memory/attention paradigm while employing high-definition transcranial direct current stimulation (HD-tDCS) to stimulate the lDLPFC. Observers were asked to maintain visual or audiovisual information in memory while executing a search task, while the validity of the memory contents for the subsequent search task could be either invalid or neutral. The results showed a faint memory-driven attentional suppression effect in sham stimulation only under the audiovisual condition. Moreover, anodal HD-tDCS facilitated attentional suppression effect in both the strength and temporal dynamics under the visual-only condition, whereas the effect was impaired or unchanged under the audiovisual condition. Surprisingly, cathodal HD-tDCS selectively improved temporal dynamics of the attentional suppression effect under the audiovisual condition. The present study revealed the differential enhancement of HD-tDCS on cognitive control over visual and audiovisual memory-driven attention among individuals with SUD.

Effect of body-related information on food attentional bias in women with body weight dissatisfaction.

Women with body weight dissatisfaction (BWD) have long-term negative assessments of their body weight, which are often associated with poor eating behavior. In this study, we investigated the effect of body-related information on the food cue processing and attention of women with BWD. Sixty-eight women were recruited and assigned to either a BWD (NPSS-F > 2) (n = 32) or a no body weight dissatisfaction (NBWD) group (NPSS-F < 1) (n = 36). We measured attentional bias to food cues (high- and low-calorie) with a food probe task after exposure to body-related information and recorded eye tracking data. Body-related images were presented prior to a pair of stimulus images (food-neutral or neutral-neutral). Body-related information and food type were repeated measure factors in our study. Our results showed that the first fixation duration bias for high-calorie foods was significantly longer than for low-calorie foods after exposure to overweight cues in the BWD group. Compared with the NBWD group, the BWD group showed longer first fixation duration bias for high-calorie foods after exposure to overweight cues. The direction for high-calorie foods was significantly more often than that for low-calorie foods in the BWD group after exposure to body-related information. Our findings suggest that compared to women with NBWD, women with BWD may be more susceptible to body-related information, resulting in increased attention to high-calorie foods.

Flexible attention system: Appearance time of split attention changes in accordance with the task difficulty level.

Although it is often assumed that spatial attention exists in the form of a unitary focus, the split-attention hypothesis proposes that attention can be simultaneously divided into two spatially noncontiguous positions and that the space in between can be ignored. However, whether split attention occurs directly based on the generation of attentional benefit or whether it requires a gradual divide from a unitary focus over time has not been clarified. In the present study, by using two spatial salient cues to direct the attention allocation of participants, we aimed to investigate whether attention requires time to divide from a unitary focus and whether the appearance time of split attention varies when the task difficulty level increases between experiments. The results showed that attention required time to divide from a unitary focus, and the position between the two cued positions was not excluded by attention when the stimulus-onset asynchrony (SOA) was 60 ms. However, as the task difficulty increased between experiments, the appearance time of split attention was earlier. These findings suggest that the appearance time of split attention has a certain flexibility and can be changed according to the task requirement, thus implying that split attention and unitary attention present some common attention mechanisms and that a split or unitary mode can be flexibly selected for an attention system.

Repetition Suppression in Visual and Auditory Modalities Affects the Sound-Induced Flash Illusion.

Sound-induced flash illusion (SiFI) refers to the illusion that the number of visual flashes is equal to the number of auditory sounds when the visual flashes are accompanied by an unequal number of auditory sounds presented within 100 ms. The effect of repetition suppression (RS), an adaptive effect caused by stimulus repetition, upon the SiFI has not been investigated. Based on the classic SiFI paradigm, the present study investigated whether RS would affect the SiFI differently by adding preceding stimuli in visual and auditory modalities prior to the appearance of audiovisual stimuli. The results showed the auditory RS effect on the SiFI varied with the number of preceding auditory stimuli. The hit rate was higher with two preceding auditory stimuli than one preceding auditory stimulus in fission illusion, but it did not affect the size of the fusion illusion. However, the visual RS had no effect on the size of the fission and fusion illusions. The present study suggested that RS could affect the SiFI, indicating that the RS effect in different modalities would differentially affect the magnitude of the SiFI. In the process of multisensory integration, the visual and auditory modalities had asymmetrical RS effects.

Visual aperiodic temporal prediction increases perceptual sensitivity and reduces response latencies.

As a predictive organ, the brain can predict upcoming events to guide perception and action in the process of adaptive behavior. The classical models of oscillatory entrainment explain the facilitating effects that occur after periodic stimulation in behavior but cannot explain aperiodic facilitating effects. In the present study, by comparing the behavior performance of participants in periodic predictable (PP), aperiodic predictable (AP) and aperiodic unpredictable (AU) stimulus streams, we investigated the effect of an aperiodic predictable stream on the perceptual sensitivity and response latencies in the visual modality. The results showed that there was no difference between PP and AP conditions in sensitivity (d') and reaction times (RTs), both of which were significantly different from those in the AU condition. Moreover, a significant correlation between d' and RTs was observed when predictability existed. These results indicate that the aperiodic predictable stimulus streams increases perceptual sensitivity and reduces response latencies in a top-down manner. Individuals proactively and flexibly predict upcoming events based on the temporal structure of visual stimuli in the service of adaptive behavior.