Advancement of membrane separation technology for organic pollutant removal.

In the face of growing global freshwater scarcity, the imperative to recycle and reuse water becomes increasingly apparent across industrial, agricultural, and domestic sectors. Eliminating a range of organic pollutants in wastewater, from pesticides to industrial byproducts, presents a formidable challenge. Among the potential solutions, membrane technologies emerge as promising contenders for treating diverse organic contaminants from industrial, agricultural, and household origins. This paper explores cutting-edge membrane-based approaches, including reverse osmosis, nanofiltration, ultrafiltration, microfiltration, gas separation membranes, and pervaporation. Each technology's efficacy in removing distinct organic pollutants while producing purified water is scrutinized. This review delves into membrane fouling, discussing its influencing factors and preventative strategies. It sheds light on the merits, limitations, and prospects of these various membrane techniques, contributing to the advancement of wastewater treatment. It advocates for future research in membrane technology with a focus on fouling control and the development of energy-efficient devices. Interdisciplinary collaboration among researchers, engineers, policymakers, and industry players is vital for shaping water purification innovation. Ongoing research and collaboration position us to fulfill the promise of accessible, clean water for all.

Effects of multi-directional step exercise with weight-shifting as an adjunct to conventional exercises on balance and gait in stroke patients.

Stroke patients have gait dysfunctions that affect their activities of daily living. Stroke patients should be able to take multi-directional steps as it is necessary to achieve an independent gait. The study aimed to examine the effects of multi-directional step exercises (MSE) along with weight-shifting as an adjunct to conventional therapeutic exercises (CTE) on functional gait performance and balance in patients with stroke. Twenty-four stroke patients (mean age 56.75 years) participated in the study and were divided into experimental and control groups. The experimental group (EG) included MSE along with weight shifting and CTE. The control group (CG) included only CTE. Treatment intervention lasted for 4 weeks. Gait and balance were measured using the functional gait assessment (FGA) and the berg balance scale (BBS), respectively. EG showed a significant improvement (p = 0.000) in both the BBS and FGA scores. In CG, a significant improvement (p = 0.000) was observed only in FGA scores. EG showed a greater improvement in scores of BBS (p = 0.000) and FGA (p = 0.000) than CG. Four weeks of MSE in conjunction with CTE were more effective in improving balance and functional gait performance compared to CTE alone in the selected stroke population.

Future Is Unlicensed: Private 5G Unlicensed Network for Connecting Industries of Future.

This paper aims to unlock the unlicensed band potential in realizing the Industry 4.0 communication goals of the Fifth-Generation (5G) and beyond. New Radio in the Unlicensed band (NR-U) is a new NR Release 16 mode of operation that has the capability to offer the necessary technology for cellular operators to integrate the unlicensed spectrum into 5G networks. NR-U enables both uplink and downlink operation in unlicensed bands, supporting 5G advanced features of ultra-high-speed, high bandwidth, low latency, and improvement in the reliability of wireless communications, which is essential to address massive-scale and highly-diverse future industrial networks. This paper highlights NR-U as a next-generation communication technology for smart industrial network communication and discusses the technology trends adopted by 5G in support of the Industry 4.0 revolution. However, due to operation in the shared/unlicensed spectrum, NR-U possesses several regulatory and coexistence challenges, limiting its application for operationally intensive environments such as manufacturing, supply chain, transportation systems, and energy. Thus, we discuss the significant challenges and potential solution approaches such as shared maximum channel occupancy time (MCOT), handover skipping, the self-organized network (SON), the adaptive back-off mechanism, and the multi-domain coexistence approach to overcome the unlicensed/shared band challenges and boost the realization of NR-U technology in mission-critical industrial applications. Further, we highlight the role of machine learning in providing the necessary intelligence and adaptation mechanisms for the realization of industrial 5G communication goals.

Q-Learning Based Fair and Efficient Coexistence of LTE in Unlicensed Band.

The increased demand for spectrum resources for multimedia communications and a limited licensed spectrum have led to widespread concern regarding the operation of long term evolution (LTE) in the unlicensed (LTE-U) band for internet of things (IoT) systems. Because Wi-Fi and LTE are diverse with dissimilar physical and link layer configurations, several solutions to achieve an efficient and fair coexistence have been proposed. Most of the proposed solutions facilitate a fair coexistence through a discontinuous transmission using a duty cycling or contention mechanism and an efficient coexistence through a clean channel selection. However, they are constrained only by fairness or efficient coexistence but not both. Herein, we propose joint adaptive duty cycling (ADC) and dynamic channel switch (DCS) mechanisms. The ADC mechanism supports a fair channel access opportunity by muting certain numbers of subframes for Wi-Fi users whereas the DCS mechanism offers more access opportunities for LTE-U and Wi-Fi users by preventing LTE-U users from occupying a crowded channel for a longer time. To support these mechanisms in a dynamic environment, LTE-U for IoT applications is enhanced using Q-learning techniques for an automatic selection of the appropriate combination of muting period and channel. Simulation results show the fair and efficient coexistence achieved from using the proposed mechanism.

Wasp Venom Toxins as a Potential Therapeutic Agent.

It is high time now to discover novel drugs due to the increasing rate of drug resistance by the pathogen organisms and target cells as well as the dependence or tolerance of the body towards the drug. As it is obvious that significant numbers of the modern day pharmaceuticals are derived from natural products, it is equally astonishing to accept that venoms of various origins have therapeutic potentials. Wasp venoms are also a rich source of therapeutically important toxins which includes short cationic peptides, kinins, polyamines and polyDNA viruses, to name a few indentified. Wasp venom cationic peptides, namely mastoparan and its analogs, show a very important potency as an antimicrobial and anticancer agents of the future. They have proven to be the better candidates due to their lesser toxic effects and higher selectivity upon chemical modification and charge optimization. They also have superiority over the conventional chemical drugs as the target cells very rarely develop resistance against them because these peptides primarily imparts its effect through biophysical interaction with the target cell membrane which is dependent upon the net charge of the peptide, its hydrophobicity and anionicity and fluidity of the target cell membranes. Besides, the other components of wasp venom such as kinins, polyamines and polyDNA viruses show various pharmacological promise in the treatment of pain, inflammatory disease, and neurodegenerative diseases such as epilepsy and aversion.

Acute renal failure following multiple hornet stings.

Hornet stings are medically important stings which can cause allergic manifestations and, in severe cases, may lead to the unusual complication of acute renal failure (ARF) and other systemic complications. ARF results from toxic or ischaemic acute tubular necrosis in a setting of haemolysis or rhabdomyolysis or both and acute allergic interstitial nephritis. Venom from hornet stings can also contribute to myocardial injury or liver impairment. Here, we report three cases of hornet stings leading to ARF. Case #1 and Case #3 recovered their renal function and body physiology after a 38-day and 15-day stay in the hospital, respectively, whereas Case #2 died. They were meticulously supported by haemodialysis along with the combination of various drug regimens.