1.
QJM
; 108(1): 69-70, 2015 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24890558
2.
Minerva Cardioangiol
; 60(4): 363-73, 2012 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22858914
RESUMO
Current therapies for treatment and prevention of sudden cardiac death have certain limitations, and a search for new therapeutic approaches is desirable to reduce the burden of sudden arrhythmic death. Gene therapy and stem cell therapy have been investigated as new, valuable tools in treating cardiac diseases such as arrhythmias. In this review, the basics of each modality, important related experimental and clinical studies, and potential advantages and limitations of these treatments will be discussed. The future success of gene and cell therapy to become practical clinical tools greatly depends on our understanding of the mechanisms of ventricular arrhythmia and the mechanisms of action of gene and cell therapy.
Assuntos
Arritmias Cardíacas/prevenção & controle , Morte Súbita Cardíaca/prevenção & controle , Terapia Genética , Insuficiência Cardíaca/terapia , Transplante de Células-Tronco , Terapia Genética/métodos , Humanos , Transplante de Células-Tronco/métodos , Resultado do Tratamento
3.
Heart
; 92(9): 1218, 2006 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16908692