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Int J Pharm ; 653: 123867, 2024 Mar 25.
Artigo em Inglês | MEDLINE | ID: mdl-38310991

RESUMO

In recent years, the rapid advancement of three-dimensional (3D) printing technology has yielded distinct benefits across various sectors, including pharmaceuticals. The pharmaceutical industry has particularly experienced advantages from the utilization of 3D-printed medications, which have invigorated the development of tailored drug formulations. The approval of 3D-printed drugs by the U.S. Food and Drug Administration (FDA) has significantly propelled personalized drug delivery. Additionally, 3D printing technology can accommodate the precise requirements of pediatric drug dosages and the complexities of multiple drug combinations. This review specifically concentrates on the application of 3D printing technology in pediatric preparations, encompassing a broad spectrum of uses and refined pediatric formulations. It compiles and evaluates the fundamental principles associated with the application of 3D printing technology in pediatric preparations, including its merits and demerits, and anticipates its future progression. The objective is to furnish theoretical underpinning for 3D printing technology to facilitate personalized drug delivery in pediatrics and to advocate for its implementation in clinical settings.


Assuntos
Impressão Tridimensional , Tecnologia Farmacêutica , Humanos , Criança , Tecnologia Farmacêutica/métodos , Composição de Medicamentos , Preparações Farmacêuticas , Medicina de Precisão , Sistemas de Liberação de Medicamentos
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