RESUMO
Pefloxacin is an antibacterial agent belonging to the group of quinolones having a methyl-carboxylic acid which possesses a high activity as compared to other quinolonic drugs. In this study we tested the efficacy and tolerability of the drug in the treatment of 25 patients with environmental L.R.T.I. (Low Respiratory Tract Infections). The microbiological and clinical characteristics of the drug were tested in this study. Excellent results were obtained in 96% of the patients treated and the tolerability was also very good.
Assuntos
Pefloxacina/uso terapêutico , Infecções Respiratórias/tratamento farmacológico , Doença Aguda , Adulto , Idoso , Broncopneumonia/tratamento farmacológico , Broncopneumonia/microbiologia , Avaliação de Medicamentos , Humanos , Masculino , Pessoa de Meia-Idade , Infecções Respiratórias/microbiologiaRESUMO
In this study, some hemorheological and coagulative parameters (blood viscosity, erythrocyte filtrability, CPA, platelet aggregation) have been evaluated in 40 patients with Chronic Respiratory Failure. The results obtained document in these patients, important hemorheologic changes. 11 patients with most serious rheologic changes have been treated with Pentossifillina. A significative improvement of the explored parameters and of the clinical condition has been checked after treatment.