RESUMO
Necrotizing tracheobronchitis due to Aspergillus spp is a rare form of invasive aspergillosis. This infection is limited to or predominant in the bronchial tree. The clinical evolution is gradual: from mild non-specific manifestations of acute tracheobronchitis to severe acute respiratory insufficiency determined by a bronchial obstruction syndrome. We report a 38 years old female with systemic lupus erythematosus treated with methylprednisolone and cyclophosphamide. She developed an invasive aspergillosis, severe respiratory failure with predominant tracheobronchial damage and upper respiratory complications.
Assuntos
Aspergilose/complicações , Bronquite/microbiologia , Hospedeiro Imunocomprometido , Traqueíte/microbiologia , Adulto , Antifúngicos/uso terapêutico , Broncoscopia , Evolução Fatal , Feminino , Dedos/patologia , Humanos , Lúpus Eritematoso Sistêmico/complicações , Necrose , Choque Séptico/complicações , Dedos do Pé/patologiaRESUMO
Necrotizing tracheobronchitis due to Aspergillus spp is a rare form of invasive aspergillosis. This infection is limited to or predominant in the bronchial tree. The clinical evolution is gradual: from mild non-specific manifestations of acute tracheobronchitis to severe acute respiratory insufficiency determined by a bronchial obstruction syndrome. We report a 38 years old female with systemic lupus erythematosus treated with methylprednisolone and cyclophosphamide. She developed an invasive aspergillosis, severe respiratory failure with predominant tracheobronchial damage and upper respiratory complications.