1.
Clin Pharmacol Ther
; 101(4): 453-457, 2017 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27864923
RESUMO
Research aimed at more fully emulating human biology in vitro has rapidly progressed in recent years with advancements in 3D tissue engineering and microphysiological systems. The initial target of such systems has been directed towards drug and chemical safety assessment, with the goal of improving sensitivity and predictive capabilities. Here we discuss recent developments of in vitro organ culture systems, and their future applications in modeling human disease.