Prevalence of hepatocellular carcinoma, liver cirhosis and HBV carriers in liver disease patients referred to Clinical Research Centre, Kemri.

The prevalence of HBsAg positivity, liver cirrhosis (LC) and hepatocellular carcinoma (HCC) is studied in 139 patients at the Clinical Research Centre of KEMRI. The prevalences were found to be 15.1%, 9.3 % and 10 % respectively. 14% of the HBsAg positives were also E antigen positive. The positivity of HBsAg in HCC was 42.9% only 15.4% in LC and 57.1% HCC had AFP compared to only 15.4% in LC. It is suggested that the findings support an association of Hepatitis B virus with LC and HCC.