Detection of acetaminophen and P-aminophenol simultaneously by an electrochemical sensor based on Fe-NC derivatives attached with Ti3C2 QDs.

In this paper, Ti3C2 QDs and Fe-ZIF-8 were synthesized by a straightforward hydrothermal method. Fe-ZIF-8 was pyrolyzed at high temperatures to obtain Fe-nanoclusters (Fe-NC). Then Fe-NC is mixed with Ti3C2 QDs to form a new composite material (Ti3C2 QDs/Fe-NC), and its microstructure and composition were analyzed by technology. The proposed material can detect acetaminophen (PA) and P-aminophenol (4-AP) simultaneously with excellent detection performance. With the best conditions, the linear ranges and detection limits were 0.50-210.00 µM, 0.03 µM (S/N = 3) and 0.50-150.00 µM, 0.06 µM (S/N = 3) for PA and 4-AP, respectively. The sensor has lower detection limits and wider linear ranges, and can successfully detect 4-AP and PA in river water and acetaminophen tablets at the same time, showing potential practical application prospects. Especially, this study reports the modification of MOF derivatives with Ti3C2 QDs for the first time, which expands the application scope of Quantum Dots and MOF derivatives.

Effectiveness of Multidisciplinary Nursing Based on Fever, Blood Sugar, and Swallowing Function Management in Patients with Acute Stroke.

Purpose: The aim of this study was to assess the effectiveness of multidisciplinary nursing based on fever, blood sugar, and swallowing function management in patients with acute stroke (AS). Methods: A total of 200 AS patients who were treated in our hospital from January 2016 to January 2020 were recruited and randomized at a ratio of 1 : 1 into a control group and a study group. The control group received standardized early rehabilitation nursing, and the study group received multidisciplinary nursing based on fever, blood sugar, and swallowing function management plus standardized early rehabilitation nursing. The patients were also assigned different blood glucose levels upon admission to a high blood glucose group or a normal blood glucose group. The clinical endpoint is clinical efficacy. Results: Multidisciplinary nursing resulted in better clinical outcomes and treatment efficiency in the patients in the study group versus standardized early rehabilitation nursing. When compared with the control group, the patients in the study group showed lower National Institute of Health Stroke Scale (NIHSS) scores, higher Barthel Index (BI) scores, lower fasting blood glucose levels and body temperature 24 hours after admission, a lower incidence of swallowing dysfunction and aspiration pneumonia 30 days after nursing, and lower C-reactive Protein (CRP) levels 7 days after nursing. The NIHSS scores of the high blood glucose group were significantly higher than those of the normal blood glucose group. Conclusion: Multidisciplinary nursing based on fever, blood sugar, and swallowing function management for patients with AS improves the clinical outcome and treatment efficiency, restores the swallowing function and blood glucose level, and ameliorates the long-term prognosis of patients.

Application of the Whole Optimization of Emergency Nursing Model United and Its Influence on Patients' Stress Response and Nursing Satisfaction.

Objective: To investigate the use of an integrated emergency nursing model with a multidisciplinary team (MDT) teaching method for practice of nursing towards multiple trauma in the emergency department and its influence on patients' stress response and nursing satisfaction. Methods: The research subjects were 120 multiple trauma patients hospitalized to our hospital's emergency department between January 2019 and January 2020, who were evenly divided into groups A (n = 60) and B (n = 60) based on the sequence of admission. For patients in group A, on the basis of whole optimization of the emergency nursing model, the MDT teaching and training were given to the nursing staff in group A. Patients in group B had their emergency nursing model completely optimized. The assessment scores of nursing staff were compared. The patients' C-reactive protein (CRP) levels in peripheral circulation, first-aid time indices, treatment effect, risk of complications & nursing contentment were all investigated. Results: Nursing personnel in group A had considerably higher achievement scores than staff nurses in group B (P < 0.001). CRP levels in group A were considerably lower following therapy (P < 0.05) than those in group B. The time it took for group A to receive first assistance was considerably less than that for group B (P < 0.001). Group A had a considerably superior treatment effect than group B (P < 0.05). Complications occurred at a lower rate in group A (P < 0.05) than in group B. Group A nurses were more satisfied than group B nurses (P < 0.05). Conclusion: The entire optimization of the emergency nursing model combined with the MDT way of teaching can abbreviate the rescue process, reduce stress, improve treatment effect & reduce the possibility of complications in multiple trauma patients in the emergency department, and patients seem to be more comfortable with this nursing model. As a result, it should become more well known.