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1.
Entropy (Basel) ; 26(8)2024 Jul 29.
Artigo em Inglês | MEDLINE | ID: mdl-39202114

RESUMO

To address the potential threat to the power grid industry posed by quantum computers and ensure the security of bidirectional communication in smart grids, it is imperative to develop quantum-safe authentication protocols. This paper proposes a semi-quantum bidirectional authentication protocol between a control center (CC) and a neighboring gateway (NG). This method uses single photons to facilitate communication between the CC and the NG. Security analysis demonstrates that the protocol can effectively resist common attack methods, including double CNOT attacks, impersonation attacks, interception-measurement-retransmission attacks, and entanglement-measurement attacks. Comparisons with other protocols reveal that this protocol has significant advantages, making it more appealing and practical for real-world applications. Finally, by simulating the protocol on the IBM quantum simulator, this protocol not only validates the theoretical framework but also confirms the practical feasibility of the protocol.

2.
Virol J ; 21(1): 60, 2024 03 07.
Artigo em Inglês | MEDLINE | ID: mdl-38454409

RESUMO

INTRODUCTION: Chlorogenic acid, the primary active component in Chinese medicines like honeysuckle, exhibits anti-inflammatory and antiviral effects. It has been demonstrated that chlorogenic acid effectively prevents and treats Duck enteritis virus (DEV) infection. This study aims to further elucidate the mechanism by which chlorogenic acid prevents DEV infection. METHODS: Duck embryo fibroblast (DEF) cells were pre-treated with chlorogenic acid before being infected with DEV. Cell samples were collected at different time points for transcriptomic sequencing, while qPCR was used to detect the proliferation of DEV. Additionally, 30-day-old ducks were treated with chlorogenic acid, and their lymphoid organs were harvested for histopathological sections to observe pathological damage. The proliferation of DEV in the lymphoid organs was also detected using qPCR Based on the transcriptomic sequencing results, NF-κB1 gene was silenced by RNAi technology to analyze the effect of NF-κB1 gene on DEV proliferation. RESULTS: Compared to the viral infection group, DEF cells in the chlorogenic acid intervention group exhibited significantly reduced DEV load (P < 0.05). Transcriptomic sequencing results suggested that chlorogenic acid inhibited DEV proliferation in DEF cells by regulating NF-κB signaling pathway. The results of RNAi silencing suggested that in the three treatment groups, compared with the DEV experimental group, there was no significant difference in the effect of pre-transfection after transfection on DEV proliferation, while both the pre-transfection after transfection and the simultaneous transfection group showed significant inhibition on DEV proliferation Furthermore, compared to the virus infection group, ducks in the chlorogenic acid intervention group showed significantly decreased DEV load in their lymphoid organs (P < 0.05), along with alleviated pathological damage such as nuclear pyretosis and nuclear fragmentation. CONCLUSIONS: Chlorogenic acid effectively inhibits DEV proliferation in DEF and duck lymphatic organs, mitigates viral-induced pathological damage, and provides a theoretical basis for screening targeted drugs against DEV.


Assuntos
Mardivirus , Vírus , Animais , Patos , Ácido Clorogênico/farmacologia , Fibroblastos , Vírus/genética , Análise de Sequência de RNA , Mardivirus/genética
3.
Huan Jing Ke Xue ; 31(5): 1192-7, 2010 May.
Artigo em Chinês | MEDLINE | ID: mdl-20623850

RESUMO

Using GC-MS 18 PAHs have been quantified in sediments from water source areas, tributaries and sewage outfalls at the reaches of Huaihe River (Huainan to Bengbu). The results show that the concentrations of total PAHs ranged from 308.12-1090.37 ng/g in sediments from water source areas and tributaries, and 1308.36-8793.16 ng/g in sediments from sewage outfalls. 3-4 rings were the dominant compounds compared to the 5-6 ring PAHs. Black carbon showed better correlation to PAHs than that of TOC. The composition characterization, principal component analysis and particular ratios of PAHs demonstrated that incomplete combustion of fossil fuels was the main source of PAHs in sediments at reaches of Huaihe River (Huainan to Bengbu), as well as a few anthropogenic releases of oil products. Ecological risk assessment indicated that, most of PAHs compounds in sediments have exceeded ER-L and ISQV-L values, among which part PAHs compounds at Yaojiawan even exceeded ER-H and ISQV-H values, showing the significant potential risk of PAHs to the ecosystem in the study area.


Assuntos
Água Doce/análise , Sedimentos Geológicos/química , Hidrocarbonetos Policíclicos Aromáticos/análise , Poluentes Químicos da Água/análise , China , Monitoramento Ambiental , Cromatografia Gasosa-Espectrometria de Massas , Análise de Componente Principal , Rios/química
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