Review: innovation through research in the North American pork industry.

This article involved a broad search of applied sciences for milestone technologies we deem to be the most significant innovations applied by the North American pork industry, during the past 10 to 12 years. Several innovations shifted the trajectory of improvement or resolved significant production limitations. Each is being integrated into practice, with the exception being gene editing technology, which is undergoing the federal approval process. Advances in molecular genomics have been applied to gene editing for control of porcine reproductive and respiratory syndrome and to identify piglet genome contributions from each parent. Post-cervical artificial insemination technology is not novel, but this technology is now used extensively to accelerate the rate of genetic progress. A milestone was achieved with the discovery that dietary essential fatty acids, during lactation, were limiting reproduction. Their provision resulted in a dose-related response for pregnancy, pregnancy maintenance and litter size, especially in maturing sows and ultimately resolved seasonal infertility. The benefit of segregated early weaning (12 to 14 days of age) was realized for specific pathogen removal for genetic nucleus and multiplication. Application was premature for commercial practice, as piglet mortality and morbidity increased. Early weaning impairs intestinal barrier and mucosal innate immune development, which coincides with diminished resilience to pathogens and viability later in life. Two important milestones were achieved to improve precision nutrition for growing pigs. The first involved the updated publication of the National Research Council nutrient requirements for pigs, a collaboration between scientists from America and Canada. Precision nutrition advanced further when ingredient description, for metabolically available amino acids and net energy (by source plant), became a private sector nutrition product. The past decade also led to fortuitous discoveries of health-improving components in ingredients (xylanase, soybeans). Finally, two technologies converged to facilitate timely detection of multiple pathogens in a population: oral fluids sampling and polymerase chain reaction (PCR) for pathogen analysis. Most critical diseases in North America are now routinely monitored by oral fluid sampling and prepared for analysis using PCR methods.

Effect of natural betaine and ractopamine HCl on whole-body and carcass growth in pigs housed under high ambient temperatures.

Betaine is an osmolyte that helps to maintain water homeostasis and cell integrity, which is essential during heat stress. We hypothesized that supplemental betaine can improve growth during heat stress and may further improve the response to ractopamine. Two studies were conducted to determine: 1) the effects of betaine in combination with ractopamine; and 2) the optimum betaine level for late finishing pigs during heat stress. Heat stress was imposed by gradually increasing temperatures over 10 d to the target high temperature of 32°C. In Exp. 1, pigs ( = 1477, BW = 91.6 ± 3 kg) were assigned within BW blocks and sex to 1 of 4 diets arranged in a 2 × 2 factorial RCB design (68 pens; 20 to 23 pigs/pen). Treatments consisted of diets without or with ractopamine (5 mg/kg for 21 d followed by 8.8 mg/kg to market) and each were supplemented with either 0 or 0.2% of betaine. Betaine reduced ( ≤ 0.05) BW (123.1 vs. 124.3 kg), ADG (0.780 vs. 0.833 kg/d), and ADFI (2.800 vs. 2.918 kg/d), but did not impact carcass characteristics. Ractopamine increased ( < 0.01) BW (125.5 vs. 121.9 kg), ADG (0.833 vs. 0.769 kg/d), G:F (0.295 vs. 0.265), HCW (94.1 vs. 90.0 kg), carcass yield (74.8 vs. 73.8%), loin depth (63.6 vs. 60.0 mm), and predicted lean percentage (53.2 vs. 51.7%) and reduced ADFI (2.822 vs. 2.896 kg/d, = 0.033) and backfat depth ( < 0.001; 20.2 vs. 22.5 mm). In Exp. 2, pigs ( = 2193, BW = 95.5 ± 3.5 kg) were allocated within BW blocks and sex to 1 of 5 treatments in a RCB design (100 pens; 20 to 24 pigs/pen). Treatments consisted of diets with 0, 0.0625, 0.125, 0.1875% of betaine, and a positive control diet with ractopamine, but not betaine. Betaine tended to decrease carcass yield quadratically ( = 0.076; 74.1, 73.5, 73.8, and 73.9 for 0, 0.0625, 0.125, 0.1875% of betaine, respectively), but did not impact other responses. Ractopamine improved ( < 0.001) BW (121.6 vs. 118.5 kg), G:F (0.334 vs. 0.295), carcass yield (74.7 vs. 73.8%), loin depth (61.7 vs. 59.0 mm), and predicted lean percentage (53.2 vs. 52.6%), and reduced backfat (18.7 vs. 20.4 mm). Collectively, data indicate that under commercial conditions, betaine did not improve performance of pigs housed under high ambient temperatures, regardless of ractopamine inclusion. Ractopamine improved whole-body growth and especially carcass growth of pigs raised under high ambient temperatures. The ability of ractopamine to stimulate growth during heat stress makes it an important production technology.

Influence of dietary -arginine supplementation of sows during late pregnancy on piglet birth weight and sow and litter performance during lactation.

Two experiments were conducted to determine the effect of feeding supplemental -Arg during late pregnancy on piglet birth weight and preweaning performance. In Exp. 1, 97 gilts and sows were allotted (gestation d 93) to receive a control diet (CON; 19.8 g standardized ileal digestible [SID] Arg/d) or the CON + 1.0% -Arg (ARG; 46.6 g SID Arg/d). Gilts and sows were weighed on gestation d 93 and 110, 48 h after farrowing, and at weaning. Data, including number born alive, number weaned, individual birth and weaning weight, and placenta weight, were recorded. Blood samples were collected on d 93 and 110 and analyzed for plasma IGF-1, insulin, and blood urea nitrogen concentration. In a second experiment, 383 sows in a commercial research farm were allotted to receive CON or ARG. An -Arg premix was provided daily by top dress beginning at gestation d 81 (±0.1 d) and fed for an average of 35 d (±0.2 d). Sows received 2.73 kg feed/d with CON sows provided 17 g SID Arg/d and ARG sows receiving a total of 44 g SID Arg/d. Litter birth weight was recorded and average birth weight was computed. In a subset of 82 sows, individual birth weights were recorded. In Exp. 1, there was a tendency for greater late pregnancy maternal BW gain ( = 0.06) in ARG compared with CON. A tendency for a parity × treatment interaction was observed for late pregnancy BW gain, with first litter sows fed ARG gaining the most, gilts fed ARG intermediate, and all other treatments gaining the least ( = 0.10). No differences between treatment groups were observed for maternal plasma IGF-1, insulin, and urea nitrogen and in progeny performance to weaning ( > 0.28). In Exp. 2, piglet birth weight was more effectively tested because of the large number of multiparous sows involved. There was a tendency for individual birth weight to decline in ARG compared with CON ( < 0.08), but birth weight distribution between <0.80 and >2.8 kg was similar. No other differences were observed ( > 0.18). In conclusion, late pregnancy supplementation with -Arg had no effect on number of pigs born alive, piglet birth weight, or lactation performance.