1.
J Pediatr Gastroenterol Nutr
; 31(3): 313-6, 2000 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-10997380
2.
Schweiz Med Wochenschr
; 105(13): 413-5, 1975 Mar 29.
Artigo
em Alemão
| MEDLINE
| ID: mdl-1124368
RESUMO
Both chenodeoxycholic acid, in the dosage administered for dissolution of gallstones, and cholic acid are completely conjugated during one passage through the liver. The glycine:taurine ratio increases with the cumulative amount of exogenous bile acids secreted, which suggests consumption of available taurine. Since conjugation with glycine compensates for deficiency of the taurine conjugating system, it can be assumed that in the normal liver and with doses not exceeding 2.5 mmoles, chenodeoxycholic acid is efficiently and completely transformed into its "physiologic" conjugated form.