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1.
Hum Vaccin Immunother ; 20(1): 2371664, 2024 Dec 31.
Artigo em Inglês | MEDLINE | ID: mdl-38961667

RESUMO

Recently, CAR-T cell therapy in hematological malignancies has received extensive attention. The objective of this study is to gain a comprehensive understanding of the current research status, development trends, research hotspots, and emerging topics pertaining to CAR-T cells in the treatment of hematological malignancies. Articles pertaining to CAR-T cell therapy for hematological malignancies from the years 2012 to 2023 were obtained and assessed from the Web of Science Core Collection (WoSCC). A bibliometric approach was employed to conduct a scientific, comprehensive, and objective quantitative analysis, as well as a visual analysis, of this particular research domain. A comprehensive analysis was conducted on a corpus of 3643 articles, which were collaboratively authored by 72 countries and various research institutions. CAR-T cell research in treating hematological malignancies shows an increasing trend each year. Notably, the study identified the countries and institutions displaying the highest level of activity, the journals with the most citations and output, as well as the authors who garnered the highest frequency of citations and co-citations. Furthermore, the analysis successfully identified the research hotspots and highlighted six emerging topics within this domain. This study conducted a comprehensive exploration and analysis of the research status, development trends, research hotspots, and emerging topics about CAR-T cells in the treatment of hematological malignancies from 2012 to 2023. The findings of this study will serve as a valuable reference and guide for researchers seeking to delve deeper into this field and determine the future direction of their research.


Assuntos
Bibliometria , Neoplasias Hematológicas , Imunoterapia Adotiva , Neoplasias Hematológicas/terapia , Humanos , Imunoterapia Adotiva/métodos , Receptores de Antígenos Quiméricos/imunologia
2.
Sci Total Environ ; 766: 144318, 2021 Apr 20.
Artigo em Inglês | MEDLINE | ID: mdl-33418264

RESUMO

Negative emissions technologies (NETs), which remove and isolate carbon dioxide from the atmosphere, are expected to play a significant role in mitigating climate change. As one of the most promising NETs, bioenergy with carbon capture and storage (BECCS) methods, which captures carbon dioxide (CO2) emissions from bioenergy plants and then stores them in geological reservoirs, are being widely used in climate change scenarios. With the increased focus on mitigating solutions, several concerns have been raised regarding the deployment of BECCS. As no science mapping analyses of evolutionary BECCS patterns have yet been made, this study sought to determine these evolution patterns using a systematic analysis approach based on science mapping and visualization analyses. Under a longitudinal framework, the conceptual BECCS evolutionary track was determined using SciMAT to elucidate the structure and dynamic aspects of the associated scientific research. The co-word network and thematic evolutionary analysis revealed five main BECCS related themes. While this study provides a systematic study of BECCS research and development, further research should continue to focus on techno-economic analyses and the ecological and environmental impacts (land-use, water, diversity, and bioenergy crops) of BECCS. An increased research focus on the emerging biochar and hydrogen production themes is expected.

3.
Saúde Soc ; 22(1): 32-43, jan.-mar. 2013.
Artigo em Português | LILACS, SES-SP | ID: lil-674698

RESUMO

Neste artigo, apontam-se inicialmente algumas questões fundamentais para o entendimento das relações entre ciências sociais e saúde desde o inicio do século XX. Posteriormente, discute-se a presença das ciências sociais na saúde pública e a constituição do campo da saúde coletiva, com a criação da Associação Brasileira de Pós- Graduação em Saúde Coletiva - ABRASCO, ao final dos anos 70. Aborda-se a definição de três eixos de pesquisa do novo campo - Política de Saúde e Organização de Serviços de Saúde, Condições de Vida e Saúde, Recursos Humanos na Saúde - e dois temas emergentes de pesquisa: trabalho e saúde, violência e saúde. Nos últimos tópicos, dedicado aos desafios para a produção do conhecimento na interface entre ciências sociais, saúde pública e saúde coletiva, a autora apresenta suas considerações sobre alguns pontos abordados por Amélia Cohn na Mesa Redonda promovida pela Revista Saúde e Sociedade em 20 de março de 2012 e os novos desafios, eixos de pesquisa e temas emergentes para a saúde coletiva e para as ciências sociais nesse campo, no contexto dos anos 2000.


Assuntos
Ciências Sociais , Comunicação e Divulgação Científica , Condições Sociais , Condições de Trabalho , Política de Saúde , Publicações Científicas e Técnicas , Mão de Obra em Saúde , Reforma dos Serviços de Saúde , Saúde Pública , Serviços de Saúde , Pesquisa
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