RESUMO
OBJECTIVE: To investigate the prevalence of Enterobius vermicularis infections among children in China from 2016 to 2021, so as to provide insights into enterobiasis control and formulation of the enterobiasis control strategy among children. METHODS: Publications pertaining to the prevalence of E. vermicularis infections among children were retrieved from Wanfang Data, CNKI, VIP and PubMed databases published from January 2016 to June 2023. Eligible publications were screened according to inclusion and exclusion criteria, and the publication bias was evaluated using the assessment tool for prevalence studies proposed by the Joanna Briggs Institute Evidence-Based Practice Resources in Australia. The study period, study areas, study subjects, sample size and number of infections were extracted from publications, and a pooled analysis was performed using a meta-analysis. A meta-regression analysis was performed with the prevalence of E. vermicularis infections as an independent variable, and sample size, source of samples, study area, study method, geographical area and province as dependent variables to identify the source of the study heterogeneity. RESULTS: A total of 66 studies were included, covering 23 provinces (municipalities, autonomous regions) in China, and with the investigations conducted between 2016 and 2021. Meta-analysis showed that the pooled prevalence of E. vermicularis infections was 4.5% [95% confidence interval (CI): (3.1%, 6.0%)] among children in China from 2016 to 2021, and the annual prevalence was 4.1% [95% CI: (2.2%, 6.5%)], 4.2% [95% CI: (2.4%, 6.6%)], 4.2% [95% CI: (2.2%, 6.8%)], 3.2% [95% CI: (1.5%, 5.4%)], 2.3% [95% CI: (0.9%, 4.3%)] and 1.1% [95% CI: (0.4%, 2.1%)] from 2016 to 2021. The pooled prevalence of E. vermicularis infections was 4.9% [95% CI: (3.4%, 6.8%)] in studies with a sample size of < 5 000 cases, which was higher than that in studies with a sample size of 5 000 cases and higher [2.1%, 95% CI: (0.2%, 3.6%)], and the pooled prevalence of E. vermicularis infections was 5.2% [95% CI: (2.9%, 8.2%)] among subjects from schools, which was higher than that among subjects from communities [4.2%, 95% CI: (2.7%, 6.0%)]. The pooled prevalence of E. vermicularis infections was 4.4% [95% CI: (2.8%, 6.2%)] among children included in comprehensive surveillance, which was higher than that among children included in specific surveillance [4.8%, 95% CI: (2.6%, 7.7%)], and the pooled prevalence of E. vermicularis infections was 5.7% [95% CI: (3.8%, 7.8%)] among children included in county-level surveys, which was higher than that among children included in city-[4.8%, 95% CI: (2.3%, 8.0%)] and province-level surveys [1.8%, 95% CI: (0.3%, 4.7%)]. In addition, the pooled prevalence of E. vermicularis infections was higher among children in southern China [11.3%, 95% CI: (7.5%, 15.7%)] than that in central China [5.2%, 95% CI: (2.8%, 8.2%)], eastern China [5.2%, 95% CI: (2.8%, 8.2%)] and southwestern China [2.6%, 95% CI: (1.4%, 4.1%)]. Meta-regression analysis identified geographical area and survey province as factors affecting the study heterogeneity. CONCLUSIONS: Currently, the overall prevalence of E. vermicularis infections is moderate among children in China, and the prevalence varies greatly in regions, with a high prevalence rate in southern China and presence of small-scale clusters. Enterobiasis surveillance and health education pertaining to enterobiasis control are required with adaptations to local circumstance to reduce the prevalence of E. vermicularis infections among children.
Assuntos
Enterobíase , Enterobius , Enterobíase/epidemiologia , Enterobíase/parasitologia , China/epidemiologia , Humanos , Criança , Prevalência , Enterobius/fisiologia , Enterobius/isolamento & purificação , Animais , Pré-Escolar , AdolescenteRESUMO
BACKGROUND: Enterobius vermicularis (E. vermicularis), also referred to as pinworm, is a widespread human intestinal parasite which predominantly occurs in young children, making their caretakers a population at risk for the transmission of this helminth. It can occasionally affect extraintestinal organs and tissues, including the female genital tract. Infestation can be asymptomatic or manifest as different kinds of gynaecological disorders, such as pelvic inflammation mimicking tumours, abnormal uterine bleeding, or vaginitis. Diagnosis is made by identifying ova in the sample collected from the perineal skin using a transparent adhesive tape or microscopic examination of resected tissue. Mebendazole is the first-line medication and should also be administered to all household members. CASE PRESENTATION: We present a case of a patient who had undergone surgery for invasive cervical cancer with an accidental finding of E. vermicularis eggs in the cervix. CONCLUSIONS: Although not very common, infestation with E. vermicularis should be considered in differential diagnoses of various gynaecological disorders accompanied by histological findings of granulomatous inflammation.
Assuntos
Enterobíase , Enterobius , Neoplasias do Colo do Útero , Humanos , Feminino , Enterobíase/diagnóstico , Enterobíase/complicações , Neoplasias do Colo do Útero/diagnóstico , Neoplasias do Colo do Útero/cirurgia , Enterobius/isolamento & purificação , Animais , Mebendazol/uso terapêutico , Colo do Útero/parasitologia , Colo do Útero/patologia , Diagnóstico Diferencial , Pessoa de Meia-Idade , AdultoRESUMO
The German cockroach Blattella germanica is commonly infected with the pinworm Blatticola blattae. To determine the effect of pinworm infection on cockroach survival, we artificially altered the pinworm infection status of cockroaches and determined the number of survival days under no-feeding conditions, with and without opportunities for fecal feeding. Four lines of the German cockroach (Wn, Wp, Nn, and Np groups) were used in the experiment. Wp and Np were pinworm-infected lines. Wn and Nn were pinworm-free lines. The 50% survival days of cockroaches in the absence of opportunities for fecal feeding were not significantly different in Wp (3.45 days) vs Wn (3.27), and in Np (4.60) vs Nn (4.48). In contrast, in the presence of fecal feeding, the 50% survival times for the pinworm-infected Wp (4.04) and Np (6.65) were significantly longer than those for the pinworm-free Wn (2.77) and Nn (5.46). The number of survival days without feeding was significantly higher in the pinworm-infected group given the opportunity to eat feces than in the non-infected group. These results suggest that pinworm infection of cockroaches during starvation, in association with fecal feeding, may be associated with longer survival.
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Fezes , Animais , Fezes/parasitologia , Blattellidae/parasitologia , Análise de Sobrevida , Enterobius/isolamento & purificação , Baratas/parasitologia , Comportamento AlimentarRESUMO
Objective: This study aimed to determine the frequency of Enterobius vermicularis in appendectomy specimens and evaluate the histopathological characteristics of adult and pediatric cases with E. vermicularis infection. Methods: Appendectomies examined from 1 January 2010, to 1 December 2020, were analysed retrospectively. Cases were divided into two groups: under 18 years (children) and 18 and over (adults). Demographic and histopathological characteristics of patients were also examined. Results: Out of 14.797 patients that underwent appendectomy, 6.130 were children and 8.667 were adults. E. vermicularis was detected in 268 patients, wherein 64.2% were children and 35.8% were adults. In the detection of E. vermicularis in appendectomy specimens, the frequency was higher in children compared to that in adults (2.85%, 1.1%, respectively) (p<0.001). Histopathologically, acute appendicitis was defined in 31.7% (n=85) of 268 cases, and E. vermicularis was found to cause a higher rate of acute appendicitis in adults (p<0.001). Conclusion: The frequency of E. vermicularis in appendectomy specimens is higher in children. However, E. vermicularis causes acute appendicitis more frequently in adults.
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Apendicite/parasitologia , Enterobíase/parasitologia , Adolescente , Adulto , Animais , Apendicectomia/estatística & dados numéricos , Apendicite/cirurgia , Apêndice/parasitologia , Apêndice/cirurgia , Criança , Enterobíase/cirurgia , Enterobius/isolamento & purificação , Feminino , Humanos , Enteropatias Parasitárias/parasitologia , Enteropatias Parasitárias/cirurgia , Masculino , Estudos RetrospectivosAssuntos
Colonoscopia/métodos , Enterobíase/diagnóstico , Eosinofilia/sangue , Fezes/parasitologia , Animais , Antinematódeos/uso terapêutico , Enterobíase/tratamento farmacológico , Enterobíase/imunologia , Enterobíase/parasitologia , Enterobius/isolamento & purificação , Eosinofilia/etiologia , Humanos , Masculino , Mebendazol/uso terapêutico , Pessoa de Meia-Idade , Sangue OcultoAssuntos
Albendazol/uso terapêutico , Anti-Helmínticos/uso terapêutico , Enterobíase/diagnóstico , Enterobius/isolamento & purificação , Tecido de Granulação/parasitologia , Ivermectina/uso terapêutico , Adulto , Animais , Emperipolese , Enterobíase/tratamento farmacológico , Enterobíase/parasitologia , Enterobíase/patologia , Feminino , Tecido de Granulação/patologia , Humanos , Larva , Linfócitos/patologia , Macrófagos/fisiologia , Neutrófilos/fisiologia , Plasmócitos/fisiologia , Reto/parasitologia , Reto/patologia , Resultado do TratamentoRESUMO
Aspiculuris tetraptera a pinworm of mice, is an important parasite in institutions with mice colonies for both research and teaching purposes. Infection with this parasite has impact on biomedical research. This is likely due to the availability of the parasite's eggs in the environment, therefore can easily be transmitted and infection is generally asymptomatic. No information regarding the prevalence, morphology or phylogeny is available on A. tetraptera from Saudi Arabia. A group of 50 laboratory mice were investigated for the presence of A. tetraptera. Worms were described morphologically and molecular characterization was attempted using 18S rRNA and Cytochrome Oxidase Subunit I genes. The prevalence of A. tetraptera infestation in the laboratory mice examined was found to be 46%. Morphological description indicated that the worms belong to A. tetraptera and this was confirmed by molecular characterization. Both regions studied have shown that the worm under investigation grouped with A. tetraptera. 18S rDNA sequences obtained in the present study showed high identity with sequences from A. tetraptera while Cytochrome c Oxidase subunit I gene (COI) sequences showed intraspecific variation resulted into two haplotypes from the isolates in the present study. A. tetraptera was recorded for the first time from Saudi Arabia. Molecular characterization has shown, based on the COI sequences, that the Saudi isolates of A. tetraptera are distinct.
Assuntos
Complexo IV da Cadeia de Transporte de Elétrons/genética , Enterobíase/parasitologia , Enterobius/genética , Proteínas de Helminto/genética , Helmintíase Animal/parasitologia , RNA de Helmintos/genética , RNA Ribossômico 18S/genética , Animais , Enterobius/isolamento & purificação , Camundongos , Filogenia , Arábia SauditaRESUMO
BACKGROUND: The Tibetan antelope Pantholops hodgsonii (Abel) (Artiodactyla: Bovidae) is an endangered species of mammal endemic to the Qinghai-Tibetan Plateau. Parasites and parasitic diseases are considered to be important threats in the conservation of the Tibetan antelope. However, our present knowledge of the composition of the parasites of the Tibetan antelope remains limited. METHODS: Large numbers of nematode parasites were collected from a dead Tibetan antelope. The morphology of these nematode specimens was observed using light and scanning electron microscopy. The nuclear and mitochondrial DNA sequences, i.e. small subunit ribosomal DNA (18S), large subunit ribosomal DNA (28S), internal transcribed spacer (ITS) and cytochrome c oxidase subunit 1 (cox1), were amplified and sequenced for molecular identification. Moreover, phylogenetic analyses were performed using maximum likelihood (ML) inference based on 28S and 18S + 28S + cox1 sequence data, respectively, in order to clarify the systematic status of these nematodes. RESULTS: Integrated morphological and genetic evidence reveals these nematode specimens to be a new species of pinworm Skrjabinema longicaudatum (Oxyurida: Oxyuridae). There was no intraspecific nucleotide variation between different individuals of S. longicaudatum n. sp. in the partial 18S, 28S, ITS and cox1 sequences. However, a high level of nucleotide divergence was revealed between the new species and its congeners in 28S (8.36%) and ITS (20.3-23.7%) regions, respectively. Molecular phylogenetic results suggest that the genus Skrjabinema should belong to the subfamily Oxyurinae (Oxyuroidea: Oxyuridae), instead of the subfamily Syphaciidae or Skrjabinemiinae in the traditional classification, as it formed a sister relationship to the genus Oxyuris. CONCLUSIONS: A new species of pinworm Skrjabinema longicaudatum n. sp. (Oxyurida: Oxyuridae) is described. Skrjabinema longicaudatum n. sp. represents the first species of Oxyurida (pinworm) and the fourth nematode species reported from the Tibetan antelope. Our results contribute to the knowledge of the species diversity of parasites from the Tibetan antelope, and clarify the systematic position of the genus Skrjabinema.
Assuntos
Antílopes/parasitologia , Enterobius/anatomia & histologia , Enterobius/classificação , Filogenia , Animais , DNA Mitocondrial/genética , Espécies em Perigo de Extinção , Enterobius/isolamento & purificação , Feminino , Trato Gastrointestinal/parasitologia , Variação Genética , Masculino , Análise de Sequência de DNA , TibetRESUMO
Objective: The purpose of this study was to determine the intestinal parasite distributions in patients who applied to the Parasitology Laboratory of Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, by evaluating the parasites retrospectively. Methods: Normal saline and stool lugol were applied for direct examination of stool samples that were sent for parasite examination; cellophane band samples were evaluated microscopically. The samples suspected to have protozoa were evaluated using modified acid fast and trichrome staining methods. We evaluated the parasitological examination results of patients who applied to our laboratory between January 2012 and December 2018. Results: A total of 2.96% of the 20,948 patients who applied had parasites in their faeces. Blastocystis spp. was detected at the highest rate (63.23%), followed by Giardia intestinalis (17.26%), Enterobius vermicularis (12.58%), Taenia saginata (2.42%), Cryptosporidium spp. (1.94%) and Entamoeba histolytica/dispar (1.45%). Conclusion: Although the prevalence of intestinal parasitic infections has decreased when compared to previous years, it still remains important. For this reason, solving infrastructure problems, providing information on personal hygiene and sanitation rules are among the most important tasks needed to reduce the prevalence of intestinal parasites.
Assuntos
Cryptosporidium/isolamento & purificação , Enterobius/isolamento & purificação , Giardia lamblia/isolamento & purificação , Enteropatias Parasitárias/epidemiologia , Adulto , Animais , Criptosporidiose/epidemiologia , Criptosporidiose/etiologia , Criptosporidiose/parasitologia , Enterobíase/epidemiologia , Enterobíase/etiologia , Enterobíase/parasitologia , Fezes/parasitologia , Feminino , Giardíase/epidemiologia , Giardíase/etiologia , Giardíase/parasitologia , Hospitais Universitários , Humanos , Enteropatias Parasitárias/etiologia , Enteropatias Parasitárias/parasitologia , Laboratórios , Masculino , Prevalência , Estudos Retrospectivos , Turquia/epidemiologiaRESUMO
OBJECTIVE: This study was designed to search for ancient parasites in abdominal content and coprolites from Bolivian mummies. MATERIALS: Twelve mummified individuals from the Andean highlands, housed at the National Museum of Archaeology (MUNARQ) in La Paz, Bolivia. METHODS: Microscopic analysis of rehydrated samples (coprolites and abdominal content), following Lutz's spontaneous sedimentation technique. RESULTS: Eggs of Enterobius vermicularis were identified in coprolites from one mummy, and capillariid eggs in the organic abdominal content from another individual. CONCLUSIONS: This is the first evidence of ancient intestinal parasites in Bolivian mummies. SIGNIFICANCE: This pioneering study focused on the search of ancient intestinal parasites in human remains of the Bolivian Andes and contributes to greater knowledge of paleoparasitology in South America. LIMITATIONS: All mummies in the MUNARQ belonged to the Andean Bolivian highlands (post-Tiwanaku era or Late Intermediate Period), although the exact provenance of the material and the associated contexts are not well recorded. SUGGESTIONS FOR FURTHER RESEARCH: Considering the great number of well-known archaeological sites and other unexplored sites in Bolivia, in addition to large collections in museums, further paleopathological and paleoparasitological molecular studies in mummies and skeletons are called for.
Assuntos
Infecções por Enoplida/parasitologia , Enterobíase/parasitologia , Indígenas Sul-Americanos/história , Múmias/parasitologia , Abdome/parasitologia , Adulto , Animais , Bolívia , Enoplídios/isolamento & purificação , Infecções por Enoplida/história , Enterobíase/história , Enterobius/isolamento & purificação , Fezes/parasitologia , Feminino , História Antiga , Humanos , Enteropatias Parasitárias/história , Enteropatias Parasitárias/parasitologia , Estágios do Ciclo de Vida/fisiologia , Masculino , Pessoa de Meia-Idade , Múmias/história , PaleopatologiaRESUMO
BACKGROUND: Enterobius vermicularis is an intestinal helminthic parasite that causes a gastrointestinal infection called enterobiasis. Children are more susceptible to infection than adults. The current study aimed to explore the prevalence of E. vermicularis infection among children in Erbil City concerning demographic factors and certain blood parameters. METHODS: A cross-sectional and analytical study was conducted on 505 children (3-10 years). Cellophane tape samples and blood samples were taken from participants. The cellophane tape samples were examined microscopically, whereas blood samples were examined using the auto-analyzer and Cobas. RESULTS: The overall prevalence of E. vermicularis infection was 27.13%, and the infection rate was non-significantly (P = 0.371) higher in females (28.85%) than in males (25.31%). The incidence of enterobiasis was directly proportional to family size. This study demonstrated that the mean serum total protein and iron levels were significantly decreased in infected children, while other trace element levels were not significantly affected. CONCLUSIONS: The prevalence of E. vermicularis is relatively lower than that in previous studies. Serum total protein and iron levels significantly decreased in the enterobiasis-positive group.
Assuntos
Proteínas Sanguíneas/análise , Enterobíase/sangue , Enterobíase/epidemiologia , Enterobius/isolamento & purificação , Ferro/sangue , Fatores Etários , Animais , Criança , Pré-Escolar , Estudos Transversais , Testes Diagnósticos de Rotina , Características da Família , Feminino , Humanos , Incidência , Iraque/epidemiologia , Masculino , Prevalência , Fatores SexuaisRESUMO
Objective: The aim of this study was to determine the distribution of intestinal parasites in patients admitted to our hospital with gastrointestinal complaints in our city harboring sociocultural and economic changes, and to show the relationship between these parasites and variables such as age, sex and year. Methods: The distribution of intestinal parasites in patients who suffered from gastrointestinal symptoms and were referred to our microbiology/parasitology laboratory from various clinics of the Sivas Cumhuriyet University Training and Research Hospital between January 2006 and December 2018 was determined. After macroscopic examination, 19,760 stool specimens were examined with Nativ-lugol, if necessary, flotation, sedimentation, trichrome and modified acid-fast, Certest Combo Card test Crypto + Giardia + Entamoeba (CerTest Biotec S.L., SPAIN) methods and 5,814 cellophane tape samples were examined with direct microscopy and the results were evaluated retrospectively. Results: Three protozoa and six helminth species were identified in the samples studied. The most frequent parasite was found to be Giardia intestinalis (6.9% n=1.363) from protozoa and Enterobius vermicularis (10.8% n=627) from helminths. Entamoeba histolytica/dispar (1.5% n=289), Cryptosporidium parvum (0.3% n=53), Ascaris lumbricoides (0.2% n=41), Trichuris trichiura (0.1% n=23), Hymenolepis nana (0.1% n=21), Taenia saginata (2.1% n=299) and Dicrocoelium dendriticum (0.01% n=1) were among other intestinal parasites. Conclusion: Between 2006-2018, while decreases in soil-borne parasitoses were observed, there was no statistically significant decrease in annual positive case rates. Despite the development of the infrastructure, parasitoses transmitted by lack of sanitation/cleaning, are still important in our province.
Assuntos
Helmintíase/parasitologia , Enteropatias Parasitárias/parasitologia , Infecções por Protozoários/parasitologia , Adolescente , Adulto , Animais , Ascaris lumbricoides/isolamento & purificação , Criança , Pré-Escolar , Cryptosporidium parvum/isolamento & purificação , Dicrocoelium/isolamento & purificação , Entamoeba/classificação , Entamoeba/isolamento & purificação , Enterobius/isolamento & purificação , Fezes/parasitologia , Feminino , Giardia lamblia/isolamento & purificação , Helmintíase/epidemiologia , Humanos , Lactente , Enteropatias Parasitárias/epidemiologia , Masculino , Pessoa de Meia-Idade , Infecções por Protozoários/epidemiologia , Estudos Retrospectivos , Taenia saginata/isolamento & purificação , Trichuris/isolamento & purificação , Adulto JovemRESUMO
Enterobius vermicularis is a common intestinal nematode of humans that can be considered relatively harmless. A polypoid lesion mimicking malignancy was detected in the rectum of a 66-year-old female patient who had been operated for sigmoid colon adenocarcinoma in the past. Histopathological examination of the lesion revealed no malignancy but there was adult E. vermicularis nematodes and eggs. In this case report, we aimed to present an enterobiasis infestation that produces non-necrotizing granuloma tissue in the rectum.
Assuntos
Pólipos do Colo/diagnóstico , Enterobíase/diagnóstico , Neoplasias Retais/diagnóstico , Idoso , Animais , Pólipos do Colo/patologia , Diagnóstico Diferencial , Enterobíase/cirurgia , Enterobius/isolamento & purificação , Feminino , Humanos , Neoplasias Retais/patologiaRESUMO
Genital tract bleeding in prepubertal girls is a rare clinical condition, which can occur for multiple reasons. It frequently generates anxiety in the family and in health care professionals. A thorough anamnesis and careful genital inspection can give important diagnostic hints; however, there are cases in which the cause remains doubtful and a complete gynecological evaluation (including cultures and vaginoscopy) is necessary. Therefore, the attending physician should always consider less frequent diagnoses in order to perform the necessary studies in a sequential and rational manner. We present the case of a preschool girl with vaginal bleeding due to pinworm endometritis, which, to our knowledge, has never been reported before as a cause of genital bleeding in prepubertal girls.
Assuntos
Endometrite/diagnóstico , Enterobíase/diagnóstico , Enterobius/isolamento & purificação , Hemorragia Uterina/etiologia , Albendazol/administração & dosagem , Animais , Anti-Helmínticos/administração & dosagem , Pré-Escolar , Endometrite/complicações , Enterobíase/tratamento farmacológico , Feminino , Exame Ginecológico , Humanos , Laparoscopia/efeitos adversos , Hemorragia Uterina/diagnóstico por imagemAssuntos
Adenoma/diagnóstico , Enterobíase/diagnóstico , Mucosa Intestinal/patologia , Neoplasias Retais/diagnóstico , Reto/patologia , Adenoma/complicações , Adenoma/parasitologia , Adenoma/cirurgia , Animais , Enterobíase/complicações , Enterobíase/parasitologia , Enterobíase/cirurgia , Enterobius/isolamento & purificação , Humanos , Achados Incidentais , Mucosa Intestinal/parasitologia , Mucosa Intestinal/cirurgia , Masculino , Pessoa de Meia-Idade , Neoplasias Retais/complicações , Neoplasias Retais/parasitologia , Neoplasias Retais/cirurgia , Reto/parasitologia , Reto/cirurgiaRESUMO
Perianal and perineal pruritus is often associated with Enterobius vermicularis in children. Although this roundworm is common in pediatric practice, most doctors are unaware that it can cause appendicular colic with/or appendicitis, severe urogenital complications, bowel perforation, and peritonitis. We report a case of a young male who presented with signs and symptoms of acute peritonitis. Dur-ing the operation, perforation of the jejunum with a purulent exudate under the transverse colon, a left lateral canal, a Douglas cavity were found as well as single enlarged mesenteric lymph nodes. Histological studies detected Enterobius vermicularis in the lumen of the appendix and jejunum, as well as in the purulent exudate in the intestinal wall and serosa. A mesenteric lymph node, histologically presented with chronic nonspecific lymphadenitis. In conclusion, infection with Enterobius vermicularis should be considered in peri-tonitis, appendicitis, and enlarged mesenteric lymph nodes, especially in young patients.
Assuntos
Enterobíase/complicações , Enterobius/isolamento & purificação , Perfuração Intestinal/complicações , Jejuno/parasitologia , Peritonite/etiologia , Doença Aguda , Adulto , Animais , Enterobíase/parasitologia , Humanos , Perfuração Intestinal/diagnóstico , Perfuração Intestinal/parasitologia , Masculino , Peritonite/diagnóstico , Peritonite/parasitologiaRESUMO
A 28-year-old man with a prior history of penetrating keratoplasty in the left eye for total corneal melt presented with a 3-day history of a red, painful left eye. On examination, he was found to have graft infiltrates. Microscopic examination of wet mount preparation of corneal scrapings revealed the presence of embryonated eggs of E. vermicularis. Cellophane (scotch) tape preparation from perianal region also revealed embryonated eggs of E. vermicularis as well as live adult worms. Ocular and adnexal involvement by E. vermicularis is extremely rare. Here, we report the first case of infection of a corneal graft with E. vermicularis.