RESUMO
RATIONALE: Blunt traumatic arteriovenous fistula (AVF) of scalp, are uncommon and most of them can be secured by simple embolization or surgical ligation of the feeders. Our goal in writing this paper is to show patients with traumatic scalp AVFs how to prevent complications and the likelihood of recurrence. PATIENT CONCERNS: Complete treatment and reduce the recurrence rate of traumatic AVF on the scalp. DIAGNOSES: Traumatic scalp AVF. INTERVENTIONS: Transarterial embolization and surgical resection. OUTCOMES: Complete resection of the AVF and subsequent angiography showed resolution of the contralateral lesion. LESSONS: Combination of endovascular embolization with subsequent surgical removal may reduce intraoperative blood loss compared with surgery alone. In addition, a well-designed scalp flap can be performed based on the angiography findings after embolization.
Assuntos
Fístula Arteriovenosa , Embolização Terapêutica , Couro Cabeludo , Humanos , Couro Cabeludo/lesões , Couro Cabeludo/irrigação sanguínea , Fístula Arteriovenosa/etiologia , Fístula Arteriovenosa/cirurgia , Embolização Terapêutica/métodos , Masculino , AdultoRESUMO
BACKGROUND: To report the diagnosis and treatment of a rare disease of intravenous leiomyomatosis (IVL) originating from the uterus, growing in the inferior vena cava (IVC) and extending into the right atrium (RA) associated with a pelvic arteriovenous fistula (AVF). This is the first reported case of IVL in the IVC and RA with pulmonary benign metastasizing leiomyoma (PBML) secondary to a pelvic AVF despite the use of GnRH agonists in a nonmenopausal woman. CASE PRESENTATION: The patient was a 50-year-old premenopausal woman with a history of surgical resection for and antiestrogen conservative drug for pulmonary benign metastasizing leiomyoma (PBML) 5 years. The patient nevertheless developed IVL in the IVC, internal iliac vein and RA accompanied by AVF. Vaginal ultrasound combined with echocardiography and computerized tomographic venography imaging assists in the diagnosis of IVL combined with AVF, with histopathology and immunohistochemistry ultimately confirming the diagnosis. The patient ultimately was performed with a combination of hysterectomy, bilateral adnexectomy, and resection of tumors in the IVC and RA without cardiopulmonary bypass and sternotomy. CONCLUSION: BML may be difficult to control with incomplete removal of the uterus and ovaries even with the use of antiestrogenic medications, and medically induced AVF resulting from fibroid surgery may accelerate this process and the development of IVL.
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Fístula Arteriovenosa , Átrios do Coração , Leiomiomatose , Neoplasias Pulmonares , Neoplasias Uterinas , Neoplasias Vasculares , Veia Cava Inferior , Humanos , Feminino , Veia Cava Inferior/patologia , Veia Cava Inferior/cirurgia , Veia Cava Inferior/diagnóstico por imagem , Pessoa de Meia-Idade , Neoplasias Uterinas/patologia , Neoplasias Uterinas/cirurgia , Fístula Arteriovenosa/cirurgia , Fístula Arteriovenosa/etiologia , Fístula Arteriovenosa/diagnóstico por imagem , Fístula Arteriovenosa/patologia , Átrios do Coração/patologia , Átrios do Coração/cirurgia , Átrios do Coração/diagnóstico por imagem , Leiomiomatose/patologia , Leiomiomatose/cirurgia , Leiomiomatose/diagnóstico por imagem , Neoplasias Pulmonares/secundário , Neoplasias Pulmonares/patologia , Neoplasias Vasculares/patologia , Neoplasias Vasculares/cirurgia , Neoplasias Vasculares/diagnóstico por imagem , Neoplasias Cardíacas/secundário , Neoplasias Cardíacas/patologia , Neoplasias Cardíacas/cirurgia , Neoplasias Cardíacas/complicações , Resultado do Tratamento , Histerectomia , Veia Ilíaca/patologia , Veia Ilíaca/diagnóstico por imagemRESUMO
We present a compelling case of an elderly male with a complex medical history who presented with sepsis secondary to a urinary tract infection. During admission, changes in his abdominal exam prompted imaging studies, which revealed a grade IV splenic laceration with a giant splenic artery pseudoaneurysm containing a suspected arteriovenous fistula component. Multidisciplinary discussion was had regarding patient management which resulted in the decision to perform an emergent splenectomy. Learning points from this case underscore the crucial role of interdisciplinary collaboration in the treatment of this pathology. Additionally, we discuss the decision-making process to support surgical intervention in the absence of clear guidelines in this exceedingly rare condition.
Assuntos
Falso Aneurisma , Fístula Arteriovenosa , Esplenectomia , Artéria Esplênica , Humanos , Falso Aneurisma/diagnóstico por imagem , Falso Aneurisma/terapia , Falso Aneurisma/etiologia , Falso Aneurisma/diagnóstico , Falso Aneurisma/cirurgia , Masculino , Artéria Esplênica/diagnóstico por imagem , Fístula Arteriovenosa/diagnóstico por imagem , Fístula Arteriovenosa/diagnóstico , Fístula Arteriovenosa/complicações , Fístula Arteriovenosa/cirurgia , Fístula Arteriovenosa/terapia , Fístula Arteriovenosa/etiologia , Baço/irrigação sanguínea , Baço/diagnóstico por imagem , Baço/lesões , Idoso , Tomografia Computadorizada por Raios XRESUMO
The number of victims with damage to the great vessels has increased in recent years due to escalation of armed conflicts. Vascular damages comprise 3% of traumatic injuries in peacetime, and their incidence increases to 15% during hostilities. False aneurysms and traumatic arteriovenous fistulas follow vascular injury in 48.9-68.7% of cases. We present open surgical treatment of traumatic arteriovenous fistulas. The issues of diagnosis, surgical tactics, algorithm of intervention and options for successful treatment are described.
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Fístula Arteriovenosa , Procedimentos Cirúrgicos Vasculares , Lesões do Sistema Vascular , Humanos , Fístula Arteriovenosa/cirurgia , Fístula Arteriovenosa/etiologia , Fístula Arteriovenosa/diagnóstico , Lesões do Sistema Vascular/cirurgia , Lesões do Sistema Vascular/diagnóstico , Lesões do Sistema Vascular/etiologia , Procedimentos Cirúrgicos Vasculares/métodos , Masculino , Resultado do Tratamento , Adulto , Extremidades/irrigação sanguínea , Extremidades/lesõesAssuntos
Fístula Arteriovenosa , Insuficiência Cardíaca , Doença Iatrogênica , Artéria Ilíaca , Humanos , Artéria Ilíaca/diagnóstico por imagem , Artéria Ilíaca/cirurgia , Insuficiência Cardíaca/etiologia , Fístula Arteriovenosa/etiologia , Fístula Arteriovenosa/cirurgia , Fístula Arteriovenosa/diagnóstico por imagem , Vértebras Lombares/cirurgia , Masculino , Adulto , Débito Cardíaco Elevado/etiologia , Resultado do Tratamento , FemininoAssuntos
Neoplasias dos Ductos Biliares , Colangiocarcinoma , Veias Hepáticas , Veia Porta , Humanos , Colangiocarcinoma/diagnóstico por imagem , Veia Porta/diagnóstico por imagem , Neoplasias dos Ductos Biliares/patologia , Neoplasias dos Ductos Biliares/diagnóstico por imagem , Neoplasias dos Ductos Biliares/cirurgia , Neoplasias dos Ductos Biliares/complicações , Veias Hepáticas/diagnóstico por imagem , Fístula Arteriovenosa/diagnóstico por imagem , Fístula Arteriovenosa/etiologia , Fístula Arteriovenosa/complicações , Fístula Arteriovenosa/cirurgia , Litíase/cirurgia , Litíase/diagnóstico por imagem , Litíase/complicações , Masculino , Pessoa de Meia-Idade , Hepatopatias/diagnóstico por imagem , Hepatopatias/diagnóstico , Hepatopatias/etiologia , Diagnóstico Diferencial , Feminino , Tomografia Computadorizada por Raios X , Resultado do TratamentoRESUMO
In this case report, we present the unique and intriguing case of a 57-year-old man who experienced exertional palpitations and shortness of breath for 5 years. He was diagnosed with idiopathic heart failure three years ago, leading to diuretic treatment. Physical examination revealed notable left lower extremity swelling, severe varicose veins, and cardiac murmurs. Echocardiography showed significant cardiac enlargement and severe functional mitral and tricuspid valve regurgitation. Computed tomography (CT) imaging uncovered a 10 mm left common iliac arteriovenous fistula, causing abnormal early filling of the inferior vena cava (IVC) and marked IVC dilation. Open surgical repair of the arteriovenous fistula resulted in symptom relief and improved cardiac function. This case underscores the importance of considering unusual causes in heart failure patients and highlights the value of early diagnosis and intervention in complex cardiac-vascular interactions.
Assuntos
Fístula Arteriovenosa , Derivação Arteriovenosa Cirúrgica , Insuficiência Cardíaca , Insuficiência da Valva Tricúspide , Humanos , Masculino , Pessoa de Meia-Idade , Fístula Arteriovenosa/diagnóstico por imagem , Fístula Arteriovenosa/etiologia , Ecocardiografia , Insuficiência Cardíaca/cirurgia , Insuficiência Cardíaca/complicações , Insuficiência da Valva Tricúspide/cirurgia , Veia Cava Inferior/diagnóstico por imagem , Veia Cava Inferior/cirurgiaAssuntos
Fístula Pancreática , Pancreatite , Veia Porta , Humanos , Veia Porta/diagnóstico por imagem , Fístula Pancreática/etiologia , Fístula Pancreática/cirurgia , Fístula Pancreática/diagnóstico por imagem , Fístula Pancreática/terapia , Pancreatite/etiologia , Pancreatite/complicações , Pancreatite/cirurgia , Masculino , Doença Aguda , Fístula Arteriovenosa/cirurgia , Fístula Arteriovenosa/complicações , Fístula Arteriovenosa/diagnóstico por imagem , Fístula Arteriovenosa/etiologia , Pessoa de Meia-IdadeRESUMO
INTRODUCTION: Arteriovenous fistula (AVF) dysfunction is a prevalent complication among maintenance hemodialysis patients. However, the factors influencing AVF patency remain unclear. To address this, we conducted a study aimed at identifying factors contributing to AVF dysfunction in this patient population. METHODS: The study compared clinical data, vascular calcification score, and laboratory data focusing on blood cell composition and coagulation in 100 maintenance hemodialysis patients in whom an AVF had been inserted from January through September of 2022. The patients were divided into a group in which the AVF functioned without issues and a group in which the AVF was dysfunctional, defined as not able to provide a blood flow of greater than 200 mL/min. FINDINGS: Patients in the 2 groups (56 in the dysfunctional AVF group and 44 in the group with satisfactory AVF function) were similar demographically. Compared with the normally functioning AVF group, the AVF dysfunction group exhibited significantly higher Agatston calcium scores (20.5 [1.28, 298] median [Q1, Q3] vs. 1.14 [0.00, 11.6]; p = 0.01), elevated triglyceride levels (1.1 [0.6, 1.2] mmol/L vs. 0.5 [0.3, 0.8]; p < 0.01), increased prothrombin activity (113 ± 22.1% vs. 99.4 ± 23.1; p < 0.01), lower prothrombin time (10.4 [9.8, 10.8] s vs. 11.0 [10.3, 11.5]; p < 0.01), higher red blood cell (RBC) counts (3.5 ± 0.7 · 1012/L vs. 3.0 ± 0.7; p < 0.01), and elevated hemoglobin levels (98.0 ± 21.8 g/L vs. 84.9 ± 24.2; p < 0.01). Higher C-reactive protein (20.2 [3.3, 20.2] mg/L vs. 17.8 [6.2, 17.8]; p = 0.01) and procalcitonin levels (0.9 [0.4, 0.9] ng/mL vs. 0.5 [0.2, 0.7]; p < 0.01) were also noted. Logistic regression analysis indicated that platelet/lymphocyte ratio, monocyte/lymphocyte ratio, and RBC count were factors associated with AVF dysfunction. Increased monocyte/lymphocyte ratio and RBC count correlated with higher risk, while a higher platelet/lymphocyte ratio was associated with lower risk. DISCUSSION: Arteriovenous fistula dysfunction in maintenance hemodialysis patients is associated with higher proportions of specific hematological parameters, particularly elevated RBC count, and altered platelet/lymphocyte and monocyte/lymphocyte ratios.
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Fístula Arteriovenosa , Derivação Arteriovenosa Cirúrgica , Humanos , Diálise Renal/efeitos adversos , Estudos Transversais , Derivação Arteriovenosa Cirúrgica/efeitos adversos , Fatores de Risco , Fístula Arteriovenosa/etiologia , Grau de Desobstrução Vascular , Estudos RetrospectivosRESUMO
We present a unique clinical case of venous congestive encephalopathy in the context of a cerebral arteriovenous fistula with clinical worsening secondary to valvular overdrainage. ICP monitoring, the different pressure settings of the programable CSF shunt and the detailed clinical description that is carried out offer us enough data to understand that this case provides important pathophysiological knowledge to a little-known disease.
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Fístula Arteriovenosa , Humanos , Fístula Arteriovenosa/etiologia , Fístula Arteriovenosa/cirurgia , Derivações do Líquido Cefalorraquidiano/efeitos adversos , Masculino , Feminino , Malformações Arteriovenosas Intracranianas/cirurgia , Malformações Arteriovenosas Intracranianas/complicações , Encefalopatias/etiologia , Pessoa de Meia-IdadeAssuntos
Falso Aneurisma , Fístula Arteriovenosa , Artéria Femoral , Veia Femoral , Doença Iatrogênica , Humanos , Falso Aneurisma/etiologia , Falso Aneurisma/diagnóstico por imagem , Falso Aneurisma/cirurgia , Fístula Arteriovenosa/etiologia , Fístula Arteriovenosa/diagnóstico por imagem , Fístula Arteriovenosa/cirurgia , Artéria Femoral/cirurgia , Artéria Femoral/diagnóstico por imagem , Artéria Femoral/lesões , Veia Femoral/diagnóstico por imagem , Veia Femoral/cirurgia , Masculino , Angiografia por Tomografia Computadorizada , Resultado do Tratamento , Lesões do Sistema Vascular/etiologia , Lesões do Sistema Vascular/diagnóstico por imagem , Lesões do Sistema Vascular/cirurgia , FemininoAssuntos
Fístula Arteriovenosa , Oclusão com Balão , Artéria Femoral , Veia Femoral , Doença Iatrogênica , Humanos , Fístula Arteriovenosa/diagnóstico por imagem , Fístula Arteriovenosa/etiologia , Fístula Arteriovenosa/terapia , Artéria Femoral/diagnóstico por imagem , Artéria Femoral/lesões , Veia Femoral/diagnóstico por imagem , Veia Femoral/lesões , Resultado do Tratamento , Lesões do Sistema Vascular/diagnóstico por imagem , Lesões do Sistema Vascular/etiologia , Lesões do Sistema Vascular/terapia , Masculino , Feminino , Pessoa de Meia-IdadeAssuntos
Fístula Arteriovenosa , Extremidade Inferior , Síndrome Pós-Trombótica , Humanos , Síndrome Pós-Trombótica/etiologia , Síndrome Pós-Trombótica/diagnóstico por imagem , Fístula Arteriovenosa/diagnóstico por imagem , Fístula Arteriovenosa/complicações , Fístula Arteriovenosa/cirurgia , Fístula Arteriovenosa/etiologia , Extremidade Inferior/irrigação sanguínea , Masculino , Feminino , Resultado do Tratamento , Pessoa de Meia-IdadeRESUMO
BACKGROUND: End-stage renal disease (ESRD) is the final stage of chronic kidney disease (CKD). AIMS: We aimed to analyze the expression differences of serum thrombomodulin (TM), platelet-activating factor (PAF), and P-selectin (CD62P) in patients with autologous arteriovenous fistula (AVF) and the correlation with vascular access function. METHODS: The case data were retrospectively analyzed. Moreover, 160 patients with AVF maintenance hemodialysis were selected as the AVF group, and 150 healthy participants were selected as the healthy control group. According to the function of vascular access, patients in the AVF group were divided into Group A (n = 50, after the first establishment of AVF), Group B (n = 64, normal vascular access function after hemodialysis treatment), and Group C (n = 46, vascular access failure). Pearson analysis was conducted to explore the correlation between serum TM, PAF, CD62P content, and vascular pathological examination indicators, to evaluate the value of TM, PAF, and CD62P levels in predicting vascular access failure in patients with AVF. RESULTS AND DISCUSSION: The serum levels of TM, PAF, and CD62P were positively correlated with the expressions of CD68 and MCP-1, respectively (p < .001). Serum TM was positively correlated with the levels of PAF and CD62P (p < .001), and PAF was positively correlated with the levels of CD62P (p < .001), respectively. Serum levels of TM, PAF and CD62P were risk factors for vascular access failure in AVF patients (p < .05). The area under the curve of serum TM, PAF and CD62P levels in predicting vascular access failure in AVF patients was 0.879. CONCLUSION: The serum levels of TM, PAF, and CD62P in AVF patients were correlated with the vascular access function of AVF patients, which was very important for maintaining the stability of vascular access function, and had certain value in predicting vascular access failure/disorder in AVF patients, and could be popularized and applied.
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Fístula Arteriovenosa , Derivação Arteriovenosa Cirúrgica , Humanos , Estudos Retrospectivos , Selectina-P , Fator de Ativação de Plaquetas , Trombomodulina , Derivação Arteriovenosa Cirúrgica/efeitos adversos , Derivação Arteriovenosa Cirúrgica/métodos , Diálise Renal/efeitos adversos , Diálise Renal/métodos , Fístula Arteriovenosa/etiologiaRESUMO
PURPOSE: The aim of this study was to investigate the effectiveness and safety of the pull-through technique through antegrade radial artery puncture without sheath insertion in balloon-assisted radiocephalic AVF maturation. METHODS: We retrospective studied a total of 62 patients with immature radiocephalic AVF, who received balloon-assisted maturation in our hospital. 15 patients received pull-through technique through radial artery without sheath insertion and 47 patients received treatment through a regular venous approach. RESULTS: The success rate of pull-through technique group and control group was 86.7% (13 out of 15), 89.1% (41 out of 46) respectively. There was no significant difference between two groups (P > 0.05). In our study, there were 2 patients in the pull-through technique group and 3 patients in the control group, which had hematoma in the vein puncture site (P = 0.59). There were also no differences in the primary patency rate between two groups at 6 months and 12 months (76.9% vs 70.7%, 38.4% vs 41.5%, respectively, P > 0.05). CONCLUSION: The pull-through technique through antegrade radial artery without sheath insertion in promoting radiocephalic AVF maturation is effective and safe.
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Fístula Arteriovenosa , Derivação Arteriovenosa Cirúrgica , Humanos , Artéria Radial/cirurgia , Derivação Arteriovenosa Cirúrgica/efeitos adversos , Oclusão de Enxerto Vascular/etiologia , Grau de Desobstrução Vascular , Estudos Retrospectivos , Fatores de Risco , Resultado do Tratamento , Diálise Renal/efeitos adversos , Fístula Arteriovenosa/etiologia , PunçõesRESUMO
BACKGROUND: Arteriovenous fistula (AVF) is currently the preferred vascular access for hemodialysis patients. However, the low maturation rate of AVF severely affects its use in patients. A more comprehensive understanding and study of the mechanisms of AVF maturation is urgently needed. METHODS AND RESULTS: In this study, we downloaded the publicly available datasets (GSE119296 and GSE220796) from the Gene Expression Omnibus (GEO) and merged them for subsequent analysis. We screened 84 differentially expressed genes (DEGs) and performed the functional enrichment analysis. Next, we integrated the results obtained from the degree algorithm provided by the Cytohubba plug-in, Molecular complex detection (MCODE) plug-in, weighted gene correlation network analysis (WGCNA), and Least absolute shrinkage and selection operator (LASSO) logistic regression. This integration allowed us to identify CTSG as a hub gene associated with AVF maturation. Through the literature search and Pearson's correlation analysis, the genes matrix metalloproteinase 2 (MMP2) and MMP9 were identified as potential downstream effectors of CTSG. We then collected three immature clinical AVF vein samples and three mature samples and validated the expression of CTSG using immunohistochemistry (IHC) and double-immunofluorescence staining. The IHC results demonstrated a significant decrease in CTSG expression levels in the immature AVF vein samples compared to the mature samples. The results of double-immunofluorescence staining revealed that CTSG was expressed in both the intima and media of AVF veins. Moreover, the expression of CTSG in vascular smooth muscle cells (VSMCs) was significantly higher in the mature samples compared to the immature samples. The results of Masson's trichrome and collagen I IHC staining demonstrated a higher extent of collagen deposition in the media of immature AVF veins compared to the mature. By constructing an in vitro CTSG overexpression model in VSMCs, we found that CTSG upregulated the expression of MMP2 and MMP9 while downregulating the expression of collagen I and collagen III. Furthermore, CTSG was found to inhibit VSMC migration. CONCLUSIONS: CTSG may promote AVF maturation by stimulating the secretion of MMP2 and MMP9 from VSMCs and reducing the extent of medial fibrosis in AVF veins by inhibiting the secretion of collagen I and collagen III.
Assuntos
Fístula Arteriovenosa , Derivação Arteriovenosa Cirúrgica , Humanos , Derivação Arteriovenosa Cirúrgica/efeitos adversos , Metaloproteinase 2 da Matriz/genética , Metaloproteinase 9 da Matriz/genética , Catepsina G , Diálise Renal/métodos , Colágeno , Colágeno Tipo I , Fístula Arteriovenosa/etiologiaRESUMO
BACKGROUNDS: There are advantages and disadvantages with closure of an arteriovenous fistula (AVF) after kidney transplantation, but some cases require closure. The general procedure for closure is angioplasty with exposure of the anastomotic site, but this is often time-consuming and complicated. We have developed a simpler, less invasive, and shorter procedure for AVF closure, in which the anastomotic site itself is not peeled off and the outflow vein close to this site is ligated using 1-0 silk. In this study, we examined the utility of this procedure. METHODS: A retrospective case series study was conducted by review of electronic medical records of patients and surgeries. All patients (n = 52) who underwent AVF closure after kidney transplantation at our hospital between January 2008 and April 2021 were reviewed. Perioperative and long-term postoperative results were examined. This study was carried out following the ethical standards of the Declaration of Helsinki and Istanbul. Donors were not from prisoners, or from those individuals who are coerced of paid. RESULTS: Simple ligation was performed for 46 patients (88.5%). The median time after renal transplantation was 40 (24.5-66.5) months. Median operative time and blood loss were 20 (12.2-30) minutes and 10 (5-15) mL, respectively. Two patients (4.3%) developed the aneurysm after the AVF closure using the simple ligation. CONCLUSION: The simple ligation technique had a relatively shorter operative time and only 2 cases had aneurysm formation. These results suggest that this technique is an option for closure of an AVF after kidney transplantation.