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1.
Zhonghua Kou Qiang Yi Xue Za Zhi ; 59(6): 640-645, 2024 Jun 09.
Artigo em Chinês | MEDLINE | ID: mdl-38880732

RESUMO

Machine vision image processing technology is extensively employed in the medical realm, particularly in dynamic navigation and robotic systems for oral implantology. It plays a pivotal role in assisting clinicians with precise implant placements, enhancing the predictability of implant restorations. The fundamental principles of machine vision image processing technology utilized in dynamic navigation and robotic systems for oral implantology primarily encompass spatial positioning and registration. However, due to variations in technical principles among different systems, their workflows and technical nuances exhibit distinctive characteristics. Therefore, commencing from the principles of spatial positioning and registration in machine vision image processing technology. This article delves into the current application landscape of machine vision in dynamic navigation and robotics for oral implantology. Its objective is to furnish valuable insights for the clinical implementation of machine vision-assisted implant technology.


Assuntos
Implantes Dentários , Processamento de Imagem Assistida por Computador , Cirurgia Assistida por Computador , Humanos , Cirurgia Assistida por Computador/métodos , Implantação Dentária/métodos , Robótica
2.
Sci Rep ; 14(1): 13888, 2024 06 16.
Artigo em Inglês | MEDLINE | ID: mdl-38880802

RESUMO

Recent studies have shown that dental implants have high long-term survival rates, indicating their effectiveness compared to other treatments. However, there is still a concern regarding treatment failure. Deep learning methods, specifically U-Net models, have been effectively applied to analyze medical and dental images. This study aims to utilize U-Net models to segment bone in regions where teeth are missing in cone-beam computerized tomography (CBCT) scans and predict the positions of implants. The proposed models were applied to a CBCT dataset of Taibah University Dental Hospital (TUDH) patients between 2018 and 2023. They were evaluated using different performance metrics and validated by a domain expert. The experimental results demonstrated outstanding performance in terms of dice, precision, and recall for bone segmentation (0.93, 0.94, and 0.93, respectively) with a low volume error (0.01). The proposed models offer promising automated dental implant planning for dental implantologists.


Assuntos
Tomografia Computadorizada de Feixe Cônico , Aprendizado Profundo , Implantes Dentários , Humanos , Tomografia Computadorizada de Feixe Cônico/métodos , Imageamento Tridimensional/métodos , Implantação Dentária/métodos , Planejamento de Assistência ao Paciente , Perda de Dente/diagnóstico por imagem
3.
Stomatologiia (Mosk) ; 103(3): 5-10, 2024.
Artigo em Russo | MEDLINE | ID: mdl-38904552

RESUMO

THE AIM OF THE STUDY: Was to determine the presence of an amoxicillin-based antibiotic in bone implant biopsies by Raman spectroscopy in an experiment. MATERIALS AND METHODS: Experimental animals (n=10, a miniature pig of the Svetlogorsk breed) were divided into 2 groups of 5 animals. Groups 1 and 2 were injected with amoxicillin 2 ml per 20 kg of body weight 30 minutes before dental implantation surgery, then group 2 was additionally injected with 1 ml per 20 kg of body weight for 5 days. Each animal has 6 implants installed. On the 1st, 3rd, 7th, 14th day, an implant-bone biopsy was removed from each animal, micro-preparations were made and Raman spectroscopy was performed to assess the peak matching of the Raman spectrum. RESULTS: In animals of the 1st and 2nd groups, the main peak of the Raman spectrum, which is closest to the values of the antibiotic spectrum of interest to us, is located closer to 1448 cm-1 and 1446 cm-1, respectively. At the same time, in both observations, the peaks relate to the spectrum of bone tissue, which cannot indicate the content of an antibiotic in the drug. CONCLUSION: No scattering spectra corresponding to the antibiotic molecule were found in any animal from both groups, regardless of the mode of administration and dosage of amoxicillin. The detected peaks corresponded to bone tissue without an antibiotic.


Assuntos
Amoxicilina , Antibacterianos , Implantes Dentários , Análise Espectral Raman , Análise Espectral Raman/métodos , Animais , Amoxicilina/análise , Amoxicilina/administração & dosagem , Suínos , Antibacterianos/análise , Antibacterianos/administração & dosagem , Biópsia , Porco Miniatura , Osso e Ossos/química , Osso e Ossos/efeitos dos fármacos , Osso e Ossos/patologia , Implantação Dentária/métodos
4.
Stomatologiia (Mosk) ; 103(3): 59-66, 2024.
Artigo em Russo | MEDLINE | ID: mdl-38904562

RESUMO

The stages of preoperative planning and surgical treatment of compromised teeth by the method of autotransplantation of a tooth are presented on the example of two clinical cases. The autotransplantation method can be considered an alternative to dental implantation when strictly adhering to the surgical protocol and careful selection of patients.


Assuntos
Implantação Dentária , Dente , Transplante Autólogo , Humanos , Implantação Dentária/métodos , Dente/transplante , Masculino , Feminino , Adulto
6.
Indian J Dent Res ; 35(1): 2-6, 2024 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-38934740

RESUMO

AIMS: To comparatively evaluate the effect of normal saline gel and ozonated saline-ozonated gel (ozone therapy) on pain, inflammation, soft tissue, and crestal bone loss in dental implant surgery. METHODS AND MATERIAL: Forty adult patients scheduled to undergo implant were randomized into two groups: Twenty patients (n = 20) received ozone therapy and controls (n = 20) received normal saline and gel during implant placement. Inflammation and pain were noted at days 1 and 7 and 3 month intervals by estimating C-reactive protein (CRP) levels and assessing visual analogue scale (VAS) scores. At 3 months, soft tissue outcomes were noted in terms of plaque index, gingival index, and pocket depth, while crestal bone loss was noted via a radiograph. RESULTS: Mean CRP levels were significantly higher in the control group as compared to that in the case group on day 1 and day 7 follow-ups (P < 0.05). Mean VAS scores for pain were also lower in the case group as compared to the control group at all follow-ups, but the difference was significant statistically only at day 1 (P = 0.061). The plaque index was significantly lower in the case group as compared to the control group (P = 0.011) at final follow-up. No significant difference between two groups was observed for crestal bone loss. CONCLUSIONS: Ozone therapy during implant placement was effective in reduction of pain, systemic inflammation, and plaque deposition in dental implant patients.


Assuntos
Proteína C-Reativa , Géis , Ozônio , Solução Salina , Humanos , Ozônio/uso terapêutico , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Proteína C-Reativa/análise , Solução Salina/uso terapêutico , Solução Salina/administração & dosagem , Implantes Dentários , Índice de Placa Dentária , Perda do Osso Alveolar , Índice Periodontal , Medição da Dor , Implantação Dentária/métodos , Inflamação
7.
Surg Radiol Anat ; 46(7): 1081-1091, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38847824

RESUMO

PURPOSE: The aim of this study is to emphasize the importance of using cone-beam computed-tomography in order to determine the anatomical structures and their variations before the treatment in patients who apply to the dentist clinic for implant treatment. METHODS: In the study, CBCT images of 500 adult patients (240 female and 260 male), aged between 21 and 82 years, who applied for implant treatment due to missing teeth, were retrospectively analyzed. Anatomical structures and variations such as nasopalatine canal(NPC), canalis sinuosus(CS), antral alveolar artery(AAA), were evaluated in multiplanar reformation(MPR) sections which are axial, sagittal and coronal can be viewed in consistence with each other. RESULTS: The incidence of anatomical variation of CS in the right region was similar according to gender. The "Funnel" appearance of the NPC shape was found most common shape in both female and male patients (n = 89; 37.1% for females and n = 71; 27.3% for males). CONCLUSION: CBCT has become the most popular 3D imaging method in dental practice especially for planning dental implants. Understanding the relationship with important anatomical structures before implant applications is crucial in dealing with potential complications that may arise afterward. Assessing significant anatomical structures by CBCT and taking precautions against possible risks facilitate the work of dentists during and after procedures.


Assuntos
Variação Anatômica , Tomografia Computadorizada de Feixe Cônico , Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Adulto , Estudos Retrospectivos , Idoso , Idoso de 80 Anos ou mais , Turquia , Adulto Jovem , Prevalência , Imageamento Tridimensional , Implantes Dentários , Implantação Dentária Endóssea/métodos , Implantação Dentária/métodos
8.
J Dent ; 146: 105034, 2024 07.
Artigo em Inglês | MEDLINE | ID: mdl-38729287

RESUMO

OBJECTIVE: To determine the current status and accuracy of robotic computer-assisted implant surgery (CAIS) applications by examining the associated clinical and experimental outcomes. DATA AND SOURCES: PubMed, Medline, and Cochrane Library databases were searched for relevant studies published between January 2000 and November 2023, and focusing on robotic CAIS in dental implant surgery. All search results were then manually reviewed to identify only the pertinent articles. Only in vitro and clinical studies were included in this narrative review, with implant placement accuracy considered the main outcome. RESULT: Based on our inclusion and exclusion criteria, we included 21 studies (with 1085 implant sites); of them, 8 were clinical studies, 12 were in vitro studies, and 1 included both an in vitro study and a case series. The ranges of the mean implant shoulder, apical, and angular deviations were respectively 0.43-1.04 mm, 0.53-1.06 mm, and 0.77°-3.77° in the clinical studies and 0.23-1.04 mm, 0.24-2.13 mm, and 0.43°-3.78° in the in vitro studies, respectively. CONCLUSION: The accuracy of robotic CAIS in dental implant procedures appears to be within the clinically acceptable ranges. However, further relevant clinical trials validating the existing evidence are needed. CLINICAL SIGNIFICANCE: Robotic CAIS can achieve clinically acceptable implant placement accuracy. This innovative technology may improve the precision and success rates of dental implant procedures, with benefit for surgeons and patients.


Assuntos
Implantação Dentária Endóssea , Implantes Dentários , Procedimentos Cirúrgicos Robóticos , Cirurgia Assistida por Computador , Humanos , Procedimentos Cirúrgicos Robóticos/métodos , Implantação Dentária Endóssea/métodos , Cirurgia Assistida por Computador/métodos , Implantação Dentária/métodos
9.
Head Face Med ; 20(1): 33, 2024 May 17.
Artigo em Inglês | MEDLINE | ID: mdl-38760840

RESUMO

BACKGROUND: Dental cone beam computed tomography (CBCT) is commonly used to evaluate cancellous bone density before dental implant surgery. However, to our knowledge, no measurement approach has been standardized yet. This study aimed to evaluate the relationship between three different regions of interest (ROI) methods on cancellous bone density at the dental implant site using dental CBCT images. METHODS: Patients' dental CBCT images (n = 300) obtained before dental implant surgery were processed using Mimics (Materialise, Leuven, Belgium). At the potential implant sites, the rectangle, cylinder, and surrounding cylinder ROI methods were used to measure bone density. Repeated measures one-way analysis of variance was performed to compare the three ROI methods in terms of measurement results. Pearson correlation analysis was performed to identify the likely pair-wise correlations between the three ROI methods. RESULTS: The density value obtained using the surrounding cylinder approach (grayscale value [GV],523.56 ± 228.03) was significantly higher than the values obtained using the rectangle (GV, 497.04 ± 236.69) and cylinder (GV,493 ± 231.19) ROI methods in terms of results. Furthermore, significant correlations were noted between the ROI methods (r > 0.965; p < 0.001). CONCLUSIONS: The density measured using the surrounding cylinder method was the highest. The choice of method may not influence the trends of measurement results. TRIAL REGISTRATION: This study was approved by the Institutional Review Board of China Medical University Hospital, No. CMUH111-REC3-205. Informed consent was waived by the Institutional Review Board of China Medical University Hospital, CMUH111-REC3-205, owing to the retrospective nature of the study.


Assuntos
Densidade Óssea , Tomografia Computadorizada de Feixe Cônico , Humanos , Tomografia Computadorizada de Feixe Cônico/métodos , Feminino , Masculino , Pessoa de Meia-Idade , Adulto , Idoso , Estudos Retrospectivos , Cuidados Pré-Operatórios/métodos , Implantação Dentária/métodos , Adulto Jovem , Implantes Dentários , Implantação Dentária Endóssea/métodos
10.
Acta Biochim Pol ; 71: 12433, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38721304

RESUMO

The study aimed to determine the osteointegration markers after dental implantation and evaluate their predictive value. The study was performed on 60 practically healthy persons who needed teeth rehabilitation using dental implants. The conical-shaped implants (CI) and hexagonal implants (HI) were used. The content of Osteopontin (OPN), Osteocalcin (OC), Alkaline Phosphatase (ALP), Osteoprotegerin (OPG), and nitric oxide (NO) was determined in patients' gingival crevicular fluid (GCF) and peri-implant sulcular fluid (PISF), collected 1, 3, and 6 months after implantation. During the 3-6 months of observation level of OPN increased in patients with CIs (<50 years > 50 years) and HIs (<50 years) (CI: <50 years F = 36.457, p < 0.001; >50 years F = 30.104, p < 0.001; HI < 50 years F = 2.246, p < 0.001), ALP increased in patients with CIs (<50 years: F = 19.58, p < 0.001; >50 years: F = 12.01; p = 0.001) and HIs (<50 years) (F = 18.51, p < 0.001), OC increased in patients <50 years (CI: F = 33.72, p < 0.001; HI: F = 55.57, p < 0.001), but in patients >50 years - on the 3 days month (CI: F = 18.82, p < 0.001; HI: F = 26.26, p < 0.001), but sharply decreased at the end of sixth month. OPG increased during 1-3 months of the observation in patients <50 years (CI: F = 4.63, p = 0.037; HI: F = 2.8927, p = 0.046), but at the end of the sixth month returned to the initial level; NO content in PISF increased in patients with CI (>50 years) during 1-6 months of the observation (F = 27.657, p < 0.001). During the post-implantation period, age-related differences in osteointegration were observed. Patients <50 years old had relatively high levels of OPN, ALP, OC, and OPG in PISF, resulting in less alveolar bone destruction around dental implants and more intensive osteointegration. These indicators may be used as biological markers for monitoring implant healing. The process of osseointegration was more intense in CIs due to their comparatively high mechanical loading.


Assuntos
Fosfatase Alcalina , Biomarcadores , Implantes Dentários , Líquido do Sulco Gengival , Osseointegração , Osteocalcina , Osteopontina , Osteoprotegerina , Humanos , Pessoa de Meia-Idade , Biomarcadores/metabolismo , Feminino , Masculino , Osteoprotegerina/metabolismo , Líquido do Sulco Gengival/metabolismo , Fosfatase Alcalina/metabolismo , Osteocalcina/metabolismo , Adulto , Osteopontina/metabolismo , Prognóstico , Óxido Nítrico/metabolismo , Implantação Dentária/métodos , Fatores de Tempo
11.
Br Dent J ; 236(10): 811-816, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38789759

RESUMO

The relationship between referring dentist and implantologist can be crucial in making the treatment journey as efficient and effective as possible for patients. There are a number of considerations to discuss to allow effective communication of options with the patient, as well as the long-term management of these cases once returned to general practice.


Assuntos
Odontologia Geral , Humanos , Implantes Dentários , Implantação Dentária/métodos , Encaminhamento e Consulta
12.
Zhonghua Kou Qiang Yi Xue Za Zhi ; 59(5): 517-522, 2024 May 09.
Artigo em Chinês | MEDLINE | ID: mdl-38637008

RESUMO

Immediate implant placement can reduce the number of treatments and the time without teeth, but it carries a higher aesthetic risk. Soft tissue augmentation can reduce the risk of gingival recession to a certain extent, improve the predictability and long-term stability of immediate implant aesthetics, and is currently a hot research topic. A comprehensive understanding of the evidence-based medicine and surgical techniques using soft tissue augmentation in immediate implant surgery can assist in clinical diagnosis, treatment decisions and improve treatment outcomes. This article elucidates the changes in soft and hard tissues after immediate implant placement, aesthetic risks, and risk factors. It also discusses the advantages, timing, material selection, and commonly used clinical techniques of soft tissue transplantation in immediate implantation, aiming to provide reference for clinical doctors to improve the effectiveness of immediate implantation.


Assuntos
Estética Dentária , Retração Gengival , Humanos , Retração Gengival/cirurgia , Implantes Dentários , Gengiva/transplante , Implantação Dentária Endóssea/métodos , Fatores de Risco , Implantação Dentária/métodos
13.
Head Neck ; 46(6): 1370-1379, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38420709

RESUMO

BACKGROUND: We sought to review our institution's experience with dental implant placement in free flap jaw reconstruction to determine factors impacting restoration of dental occlusion. METHODS: Exactly 48 patients underwent free flap jaw reconstruction with or without dental restoration from 2017 to 2022. Primary outcome was achievement of restored dental occlusion after jaw free flap reconstruction. RESULTS: A total of 48 patients with a mean age of 59.8 ± 16.4 years underwent jaw reconstruction from 2017 to 2022. Ten patients (20.8%) received osteointegrated dental implants. Two patients received a temporary dental prosthesis, 12 ± 4 months after initial reconstruction. Three patients received a final prosthesis, with a mean time to final prosthesis of 17.7 ± 12.4 months. Five patients did not receive any prosthesis despite placement of implants. CONCLUSION: A minority of patients received dental implant placement with free flap jaw reconstruction and only a small subset of these received a definitive dental prosthesis.


Assuntos
Retalhos de Tecido Biológico , Humanos , Pessoa de Meia-Idade , Feminino , Masculino , Idoso , Estudos Retrospectivos , Adulto , Implantação Dentária Endóssea/métodos , Procedimentos de Cirurgia Plástica/métodos , Resultado do Tratamento , Implantes Dentários , Implantação Dentária/métodos , Reconstrução Mandibular/métodos
14.
BMC Oral Health ; 23(1): 384, 2023 06 12.
Artigo em Inglês | MEDLINE | ID: mdl-37308877

RESUMO

BACKGROUND: The morphologic and dimensional alveolar bone is significant for resorption in the first 3 months after tooth removal because they restrict treatment outcomes with respect to function and esthetic. Following teeth extraction, the width and height of the alveolar ridge contour are reduced in both the horizontal and vertical dimensions. Following implant placement, the gingival morphology should be changed minimally compared to pre-extraction. Surrounding natural-like tissue is also an ultimate goal of the dental implant treatment, which is correlated with the cervical third contour on the anatomical tooth, for comfortable cleansing, food impaction avoidance, and esthetics. PURPOSE: To evaluate the peri-implant soft tissue changes after immediate implant placement (IIP) with the use of a customized titanium healing abutment in the posterior teeth. METHOD: Digital impressions using the intraoral scanner (MEDIT i500) were taken from 30 patients. Customized titanium healing abutments were designed and milled before extraction. Flapless extractions were done using surgical guides, 32 immediate implants placement were done in posterior areas, and healing abutments were placed. Soft tissues were scanned during pre-operation, and post-surgery during the 1st, 3rd, and 6th months. A 3D analysis program (Final Surface) evaluated the gingival margin distance, height, contour width, and volume in each period. SPSS was used to analyze the data with a p-value = 0.05. The between-time interval comparisons were done and the analysis was done using a Multivariate test. RESULTS: Customized titanium healing abutments used in immediate implantation maintained optimal peri-implant mucosa. In intermittent periods, there was no significant reduction in all aspects of the margin distances and heights. During the entire period, the margin height reduction on the buccal, lingual, mesial, and distal was 0.63 mm, 0.93 mm, 0.08 mm, and 0.24 mm, respectively, and contour width reduction on the buccal, lingual, and buccolingual was 0.59 mm, 0.43 mm, and 1.03 mm, respectively. There was a significant reduction in the total buccolingual contour width in the 1st month and total volume in the 3rd to 6th months. CONCLUSIONS: Immediate implant placement with customized titanium healing abutment can achieve the optimal peri-implant mucosa and this protocol is an alternative for soft tissue management.


Assuntos
Implantação Dentária , Implantes Dentários , Humanos , Titânio , Cicatrização , Implantação Dentária/instrumentação , Implantação Dentária/métodos
15.
J Clin Periodontol ; 50 Suppl 25: 83-95, 2023 05.
Artigo em Inglês | MEDLINE | ID: mdl-35088421

RESUMO

AIM: To identify and report outcome measures and methods of assessment on soft tissue augmentation interventions in the context of dental implant therapy reported in clinical studies published in the last 10 years. MATERIALS AND METHODS: The protocol of this Preferred Reporting Items of Systematic Reviews and Meta-Analyses (PRISMA) 2020-compliant systematic review was registered in PROSPERO (CRD42021252214). A literature search was conducted to identify articles that met the pre-established eligibility criteria. Data of interest, with an emphasis on outcome measures, were extracted. For each outcome, specific methods and timing of assessment were described in detail. Following a critical qualitative analysis of the data, outcome measures were categorized. Primary outcomes were identified, and the frequency of reporting in the selected articles was calculated. Additionally, risk-of-bias assessments were performed for individual articles and primary outcomes. RESULTS: Ninety-two articles, of which 39 reported randomized controlled trials (RCTs), 20 non-RCTs, and 33 case series studies, were selected. Outcome measures were categorized into either investigator-evaluated outcome measures (i.e., clinical, digital imaging, aesthetic, histological, biomarker, and safety) or patient-reported outcome measures (PROMs). Clinical outcomes were the most frequently reported type of outcome. Considering all categories, the most frequently reported primary outcomes were facial mucosa thickness assessed with clinical methods (22.83%), facial keratinized mucosa width assessed with clinical methods (19.57%), facial mucosal margin position/recession assessed with clinical methods (18.48%), facial mucosa thickness assessed with digital imaging methods (11.96%), facial soft tissue volume assessed with digital imaging methods (9.78%), and supracrestal tissue height assessed with clinical methods (9.78%). No distinguishable patterns of association between specific types or quality (level of bias) of clinical studies and the choice of primary outcomes were observed. CONCLUSIONS: Clinical research on peri-implant soft tissue augmentation has progressively increased in the last 10 years. Although clinical outcome measures were the most frequently reported outcomes in the selected literature, trends in the field are indicative of a shift from traditional clinical assessment methods to the use of digital technologies. PROMs were generally under-reported but should be considered an integral methodological component in future clinical studies.


Assuntos
Implantes Dentários , Humanos , Estética Dentária , Mucosa , Avaliação de Resultados em Cuidados de Saúde , Implantação Dentária/métodos
16.
Clin Oral Implants Res ; 33(12): 1273-1281, 2022 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-36239539

RESUMO

OBJECTIVES: Registration of intra-oral surface scans to cone beam computer tomography (CBCT) is critical in the digital workflow for static computer-aided implant surgery (sCAIS). This study aimed to assess the impact of CBCT field of view (FoV) on the precision of digital intra-oral scan registration. MATERIALS AND METHODS: Cone beam computer tomography data and intra-oral scans from 20 patients were included. Small FoV CBCT's were created by digitally segmenting a large FoV into three sextants. Virtual implant planning was performed. Digital intra-oral scans were repeatedly registered onto their corresponding large and small FoV CBCT datasets. The distances and angulations between the matching implant positions of each repeated registration were used to determine the precision of the registration process. Wilcoxon Signed Rank Paired Tests were used to compare the differences between large FoV and small FoV. The threshold for statistical significance was set at p = .05. RESULTS: Differences in 3D implant position based on the registration precision between small FoV and large FoV present at both the implant entry point (0.37 ± 0.25 mm vs 0.35 ± 0.23 mm, p = .482) and implant tip (0.49 ± 0.34 mm vs 0.37 ± 0.24 mm, p < .001). Differences in overall angular precision were observed between small FOV and large FoV (1.43 ± 1.36° vs 0.51 ± 0.38°, p < .001). CONCLUSION: CBCT with a small FoV is accompanied by greater precision errors in intra-oral scan registration. However, when sufficient well-distributed teeth are visible in small FoV CBCT, the precision of digital intra-oral scan registration appears to be within clinically acceptable limits for sCAIS.


Assuntos
Tomografia Computadorizada de Feixe Cônico , Implantação Dentária , Boca , Cirurgia Assistida por Computador , Humanos , Implantação Dentária/métodos , Boca/diagnóstico por imagem
17.
Rev. cuba. estomatol ; 59(2): e3544, abr.-jun. 2022. graf
Artigo em Espanhol | LILACS, CUMED | ID: biblio-1408393

RESUMO

Introducción: La elevación de seno maxilar con implante dental simultáneo, sin el uso de substitutos óseos, ha retomado la teoría del potencial de neoformación ósea, que el coágulo de sangre alojado bajo la membrana de Schneider por sí solo presenta. Excluyendo así la necesidad de materiales exógenos. Objetivo: Exponer la efectividad de la elevación de seno maxilar con implante dental simultáneo, sin el uso de injerto, mediante la evaluación de la cantidad de ganancia ósea vertical. Presentación de casos: Caso 1: Paciente de 62 años, género femenino, que fue sometida a una elevación de seno maxilar sin injerto e implante dental simultáneo, con técnica de ventana lateral debido a altura ósea reducida de 5,24 mm. Luego del período de seguimiento tomográfico de 12 meses, después de la carga protésica, se logró una altura ósea vertical de 10,2 mm, lo que dio como resultado una ganancia ósea vertical de 4,96 mm. Caso 2: Paciente de 48 años, género femenino, que fue sometida a una elevación de seno maxilar sin injerto e implante dental simultáneo, con técnica transalveolar, mediante el uso de piezoeléctrico debido a una altura ósea reducida de 8,33 mm. Luego del período de seguimiento radiográfico de 4 meses, antes de la carga protésica, se logró una altura ósea vertical de 11,55 mm, lo que dio como resultado una ganancia ósea vertical de 3,19 mm. Conclusiones: Con base en estos 2 informes de casos, la elevación de seno maxilar e implante dental simultáneo sin injerto se asocian con la reducción de la morbilidad quirúrgica, menor probabilidad de procesos infecciosos y menor costo de la cirugía. Por lo tanto, puede considerarse una alternativa quirúrgica para la colocación de implantes en el maxilar posterior superior debido a deficiencias óseas verticales, independientemente de la técnica (lateral o transalveolar(AU)


Introduction: Maxillary sinus lift with simultaneous dental implantation without using bone substitutes, reapproaches the theory about the bone neoformation potential of the blood clot housed under the Schneider membrane, all by itself, thus excluding the need to use exogenous materials. Objective: Discuss the effectiveness of graftless maxillary sinus lift with simultaneous dental implant placement through an evaluation of the amount of vertical bone gain. Case presentation: Case 1: Female 62-year-old patient undergoing graftless maxillary sinus lift with simultaneous dental implantation by lateral window technique due to a reduced bone height of 5.24 mm. After a 12-month tomographic follow-up period subsequent to prosthetic loading, a 10.2 mm vertical bone height was achieved, resulting in 4.96 mm vertical bone gain. Case 2: Female 48-year-old patient undergoing graftless maxillary sinus lift with simultaneous dental implantation by transalveolar technique using a piezoelectric generator due to a reduced bone height of 8.33 mm. After a 4-month radiographic follow-up period, before prosthetic loading, an 11.55 mm vertical bone height was achieved, resulting in 3.19 mm vertical bone gain. Conclusions: According to these two case reports, graftless maxillary sinus lifting with simultaneous dental implantation is associated to reduced surgical morbidity, a lesser probability of infectious processes and lower surgical costs. It may therefore be considered to be a surgical alternative for implant placement in the posterior maxilla due to vertical bone deficiencies, regardless of the technique used (lateral or transalveolar(AU)


Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Implantação Dentária/métodos , Levantamento do Assoalho do Seio Maxilar/métodos , Assistência ao Convalescente , Custos e Análise de Custo
18.
Bull Exp Biol Med ; 172(2): 276-281, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34855081

RESUMO

We examined alveolar bone samples in the area of on-bone fixation of a free gingival graft performed during surgery in patients aged 37-55 years with a diagnosis of secondary partial adentia of the upper and lower jaws. Six months after fixation of the graft in the alveolar bone, foci of neoosteogenesis were found in the contact zone. They were characterized by the appearance of appositional lines, cords of basophilic osteoblasts, and growing osteons. An immunohistochemical study revealed an increase in the number of CD44+, CD29+, and osteocalcin+ cells in the layer of the outer circumferential lamellae, primary osteons, and the lining of the Haversian canals. TGF-ß1+ cells were located in the intertrabecular reticular tissue and wall of microvessels. The results indicate activation of mesenchymal stem cells in the area of localization of the graft and differentiating osteoblasts. The observed osteoinductive effect of free gingival graft is associated with its participation in reorganization in MSC and induction of morphogenetic molecules.


Assuntos
Processo Alveolar/fisiologia , Implantação Dentária/métodos , Gengiva/transplante , Arcada Parcialmente Edêntula/terapia , Osseointegração/fisiologia , Adulto , Enxerto de Osso Alveolar/métodos , Processo Alveolar/citologia , Aumento do Rebordo Alveolar/métodos , Remodelação Óssea/genética , Diferenciação Celular/genética , Feminino , Retalhos de Tecido Biológico/fisiologia , Gengiva/metabolismo , Gengiva/patologia , Humanos , Receptores de Hialuronatos/genética , Receptores de Hialuronatos/metabolismo , Integrina beta1/genética , Integrina beta1/metabolismo , Arcada Parcialmente Edêntula/genética , Arcada Parcialmente Edêntula/patologia , Arcada Parcialmente Edêntula/fisiopatologia , Masculino , Células-Tronco Mesenquimais/citologia , Células-Tronco Mesenquimais/fisiologia , Pessoa de Meia-Idade , Osseointegração/genética , Osteocalcina/genética , Osteocalcina/metabolismo , Osteogênese/genética , Fator de Crescimento Transformador beta1/genética , Fator de Crescimento Transformador beta1/metabolismo
19.
Biomed Res Int ; 2021: 9910596, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34722776

RESUMO

Macrophages are important immune cells that participate in the regulation of inflammation in implant dentistry, and their activation/polarization state is considered to be the basis for their functions. The classic dichotomy activation model is commonly accepted, however, due to the discovery of macrophage heterogeneity and more functional and iconic exploration at different technologies; some studies have discovered the shortcomings of the dichotomy model and have put forward the concept of alternative activation models through the application of advanced technologies such as cytometry by time-of-flight (CyTOF), single-cell RNA-seq (scRNA-seq), and hyperspectral image (HSI). These alternative models have great potential to help macrophages divide phenotypes and functional genes.


Assuntos
Ativação de Macrófagos/imunologia , Macrófagos/classificação , Macrófagos/fisiologia , Animais , Implantação Dentária/métodos , Expressão Gênica/genética , Perfilação da Expressão Gênica/métodos , Humanos , Ativação de Macrófagos/fisiologia , Macrófagos/imunologia , Análise de Sequência de RNA/métodos , Transcriptoma/genética
20.
Sci Rep ; 11(1): 20024, 2021 10 08.
Artigo em Inglês | MEDLINE | ID: mdl-34625591

RESUMO

The use of immediate implants in the aesthetic area is a technique widely used in modern implantology. The characteristics of the patient, the implant, and the surgical procedure used may influence the final results. The aim was to assess whether the implant design affects primary (P.S.) and secondary stability (S.S.), bone level (B.L.), and PES/WES evaluation. Twenty implants with two different designs (n = 10) were immediately placed and randomly located in the upper anterior maxilla with no grafting material. Implant-Stability-Quotient (ISQ), B.L., and Pink-Esthetic-Score/White-Esthetic-Score (PES/WES) were evaluated. Shapiro-Wilk normality test was performed to determine the sample normality, as the data did not follow a normal distribution, the Wilcoxon-Mann-Whitney test was applied (p < 0.05). ISQ was determined at placement (PS): control 59.1 (C.I.54.8-63.3); experimental 62.2(C.I.60.1-64.2) and three months after placement (SS): control 62.2.1 (C.I.53.3-71.0); experimental 67.2(C.I.65.8-68.5). The BL was measured at three months after placement: control 0.38 mm (C.I.- 0.06 to + 0.83); experimental 0.76 mm (C.I.0.33-1.19) and at 12 months post-loading: control 0.07 mm (C.I.- 0.50-0.65); experimental 0.90 mm (C.I.0.38-1.42). PES/WES values were evaluated for the control group: 15 (C.I.12.68-17.32), and for the experimental group 15.20 (C.I.11.99-18.41). No significant differences were shown between both implant designs. A good grade of osseointegration and primary/secondary stability was achieved, as well as proper maintenance of crestal bone and adequate PES/WES scores. The criteria for selection for the ideal patient for immediate implant placement is essential.ClinicalTrials Protocol ID: NCT04343833.


Assuntos
Implantação Dentária/métodos , Implantes Dentários , Estética Dentária , Idoso , Idoso de 80 Anos ou mais , Método Duplo-Cego , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Osseointegração , Fatores de Risco , Alvéolo Dental/cirurgia , Resultado do Tratamento
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