RESUMO
With rapid advancements in health and human-computer interaction, wearable electronic skins (e-skins) designed for application on the human body provide a platform for real-time detection of physiological signals. Wearable strain sensors, integral functional units within e-skins, can be integrated with Internet of Things (IoT) technology to broaden the applications for human body monitoring. A significant challenge lies in the reliance of most existing wearable strain sensors on rigid external power supplies, limiting their practical flexibility. In this study, we present an innovative strategy to fabricate glutaraldehyde (GA)-poly(vinyl alcohol) (PVA)/cellulose nanocrystals (CNC)/Poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) conductive hydrogels through multiple hydrogen bonding systems. Combining the advantageous rheological properties of the precursor solution and the high specific surface area after freeze-thaw cycling, we have created a self-powered sensing system prepared by large-area printing using direct ink writing (DIW) printing. The resulting conductive hydrogel exhibits commendable mechanical properties (411 KPa), impressive stretchability (580 %), and robust self-healing capabilities (>98.3 %). The strain sensor, derived from the conductive hydrogel, demonstrates a gauge factor (GF) of 2.5 within a stretching range of 0-580 %. Additionally, the resultant supercapacitor displays a peak energy density of 0.131 mWh/cm3 at a power density of 3.6 mW/cm3. Benefiting from its elevated strain response and remarkable power density features, this self-powered strain sensing system enables the real-time monitoring of human joint motion. The incorporation of a 5G transmission module enhances its capabilities for remote data monitoring, thereby contributing to the progress of wireless tracking technologies for self-powered electronic skin.
Assuntos
Condutividade Elétrica , Eletrodos , Hidrogéis , Dispositivos Eletrônicos Vestíveis , Hidrogéis/química , Humanos , Tecnologia sem Fio , Poliestirenos/química , Celulose/química , Álcool de Polivinil/química , Nanopartículas/química , Fontes de Energia Elétrica , Propriedades de Superfície , Tamanho da Partícula , ImpressãoRESUMO
PURPOSE: There is currently a strong trend in developing RF coils that are high-density, lightweight, and highly flexible. In addition to the resonator structure of the RF coil itself, the balun or cable trap circuit serves as another essential element in the functionality and sensitivity of RF coils. This study explores the development and application of reproducible highly miniaturized baluns in RF coil design. METHODS: We introduce a novel approach to producing Bazooka baluns with printed coaxial capacitors, enabling the achievement of significant capacitance per unit length. Rigorous electromagnetic simulations and thorough hardware fabrication validate the efficacy of the proposed design across various magnetic field strengths, including 1.5 T, 3 T, and 7 T MRI systems. RESULTS: Bench testing reveals that the proposed balun can achieve an acceptable common-mode rejection ratio even when it is highly miniaturized. The use of printed capacitors allows for a notable reduction in balun length and ensures high reproducibility. Findings demonstrate that the proposed balun exhibits no RF field distortion even when placed close to the sample, making it suitable for flexible coils, wearable coils, and high-density coils, particularly in high-field MRI. CONCLUSION: The reproducibility inherent in the manufacturing process of printed coaxial capacitors allows for simple fabrication and ensures consistency in production. These advancements pave the way for the development of flexible coils, wearable coils, and high-density coils.
Assuntos
Capacitância Elétrica , Desenho de Equipamento , Imageamento por Ressonância Magnética , Imageamento por Ressonância Magnética/instrumentação , Reprodutibilidade dos Testes , Imagens de Fantasmas , Miniaturização , Ondas de Rádio , Humanos , Simulação por Computador , Impressão , Campos MagnéticosRESUMO
Piezoelectric biomaterials hold a pivotal role in the progression of bioelectronics and biomedicine, owing to their remarkable electromechanical properties, biocompatibility, and bioresorbability. However, their technological potential is restrained by certain challenges, including precise manipulation of nanobiomolecules, controlling their growth across nano-to-macro hierarchy, and tuning desirable mechanical properties. We report a high-speed thermal-electric driven aerosol (TEA) printing method capable of fabricating piezoelectric biofilms in a singular step. Electrohydrodynamic aerosolizing and in situ electrical poling allow instantaneous tuning of the spatial organization of biomolecular inks. We demonstrate TEA printing of ß-glycine/polyvinylpyrrolidone films, and such films exhibit the piezoelectric voltage coefficient of 190 × 10-3 volt-meters per newton, surpassing that of industry-standard lead zirconate titanate by approximately 10-fold. Furthermore, these films demonstrate nearly two orders of magnitude improvement in mechanical flexibility compared to glycine crystals. We also demonstrate the ultrasonic energy harvesters based on the biofilms, providing the possibility of wirelessly powering bioelectronics.
Assuntos
Aerossóis , Aerossóis/química , Tecnologia sem Fio , Biofilmes/crescimento & desenvolvimento , Eletricidade , Materiais Biocompatíveis/química , Chumbo/química , Impressão , Glicina/químicaRESUMO
Rapid quantitative testing of illegal drugs is urgently needed for precisely cracking down on drug crimes. Herein, an optimized paper-based surface-enhanced Raman spectroscopy (SERS) platform with patterned printing of plasmonic nanoparticles was constructed for the on-site quick testing of illegal drugs in urine. The filter paper was first coated with a layer of positive-charged chitosan, so as to reduce its roughness by filling the holes of the cellulose matrix and enhance the adhesion of negative-charged silver ink. Subsequently, hydrophobic modification was performed based on the binary silylation reaction, which could obviously improve the sensitivity of the paper-based SERS substrate by concentrating the amount of analyte. Meanwhile, SERS-active silver ink was fabricated and further printed on the surface of the above modified paper with custom-designed pattern (3 × 6). The performance of this SERS platform was assessed by using crystal violet (CV) as a model tag, and the obtained results proved it possesses excellent sensitivity and reproducibility, in which the relative standard deviation (RSD) dropped remarkably. More importantly, as a proof of concept, rapid detection of standard methylamphetamine (MAMP), one of the most widely abused drugs, was achieved with a limit of detection (LOD) of 1.43 ppb using a portable Raman spectrometer. And it also had a good capability in human urine sample detection, with a correlation index (R2) up to 0.9927. This optimized paper-based SERS platform was easily manufactured, cheap, and portable, providing a new strategy for the on-site detection of illicit drugs.
Assuntos
Drogas Ilícitas , Papel , Prata , Análise Espectral Raman , Análise Espectral Raman/métodos , Drogas Ilícitas/urina , Drogas Ilícitas/análise , Humanos , Prata/química , Nanopartículas Metálicas/química , Propriedades de Superfície , Limite de Detecção , Impressão , Tinta , Detecção do Abuso de Substâncias/métodos , Metanfetamina/urina , Metanfetamina/análiseRESUMO
For this article, a low-cost, compact, and flexible inkjet-printed electromagnetic sensor was investigated for its chemical and biomedical applications. The investigated sensor design was used to estimate variations in the concentration of chemicals (ethanol and methanol) and biochemicals (hydrocortisone-a chemical derivative of cortisol, a biomarker of stress and cardiovascular effects). The proposed design's sensitivity was further improved by carefully choosing the frequency range (0.5-4 GHz), so that the analyzed samples showed approximately linear variations in their dielectric properties. The dielectric properties were measured using a vector network analyzer (VNA) and an Agilent 85070E Dielectric Probe Kit. The sensor design had a resonant frequency at 2.2 GHz when investigated without samples, and a consistent shift in resonant frequency was observed, with variation in the concentrations of the investigated chemicals. The sensitivity of the designed sensor is decent and is comparable to its non-flexible counterparts. Furthermore, the simulation and measured results were in agreement and were comparable to similar investigated sensor prototypes based on non-flexible Rogers substrates (Rogers RO4003C) and Rogers Droid/RT 5880), demonstrating true potential for chemical, biomedical applications, and healthcare.
Assuntos
Nanopartículas Metálicas , Prata , Prata/química , Nanopartículas Metálicas/química , Técnicas Biossensoriais/métodos , Técnicas Biossensoriais/instrumentação , Fenômenos Eletromagnéticos , Etanol/química , Etanol/análise , Impressão , Hidrocortisona/química , Hidrocortisona/análise , Metanol/química , Polietilenotereftalatos/químicaRESUMO
Smart photochromic and fluorescent textile refers to garments that alter their colorimetric properties in response to external light stimulus. Cotton fibers have been reported as a main resource for many textile and non-textile industries, such as automobiles, medical devices, and furniture applications. Cotton is a natural fiber that is distinguished with breathability, softness, cheapness, and highly absorbent. However, there have been growing demands to find other resources for cotton textiles at high quality and low cost for various applications, such as sensor for harmful ultraviolet radiation. Herein, we present a novel method toward luminescent and photochromic nonwoven textiles from recycled cotton waste. Using the screen-printing technology, a cotton fabric that is both photochromic and fluorescent was developed using aqueous inorganic phosphor nanoparticles (10-18 nm)-containing printing paste. Both CIE Lab color coordinates and photoluminescence spectra showed that the transparent film printed on the nonwoven fabric develops a reversible green emission (519 nm) under ultraviolet light (365 nm), even at low pigment concentration (2%) in the printing paste. Colorfastness of printed fabrics showed high durability and photostability.
Assuntos
Celulose , Fibra de Algodão , Estrôncio , Fibra de Algodão/análise , Celulose/química , Estrôncio/química , Têxteis , Raios Ultravioleta , Dispositivos Eletrônicos Vestíveis , Luminescência , Óxido de Alumínio/química , Impressão , Processos Fotoquímicos , ReciclagemRESUMO
Background: Chronic n-Hexane poisoning is prevalent among workers in small and micro printing industries in China. Despite this, there is limited research on occupational health risk assessment in these sectors. Conducting comprehensive risk assessments at key positions and proposing effective countermeasures are essential. Methods: Data were collected from 84 key positions across 32 small and micro-sized printing enterprises. Air samples were tested for n-Hexane exposure levels in accordance with Chinese standards. Five risk assessment models were employed: COSHH, EPA, MOM, ICMM, and Technical Guide GBZ/T 289-2017 of China. The consistency of results across these models was analyzed. Results: Workers in 84 job positions were categorized into four exposure groups, with exposure to n-Hexane for 8-10 h daily, 5-6 days weekly. Most positions operated with low automation levels (96.9% in printing, 5.9% in oil blending, and 42.9% in pasting), while others were manual. Localized ventilation rates were notably low in oil blending (23.5%), cleaning (14.3%), and pasting (9.5%) groups. n-Hexane concentrations exceeded Chinese occupational limits in 15.6% of printing, 17.7% of oil blending, and 21.4% of cleaning groups. Risk assessment models identified over 60% of work groups as high risk. Significant differences (p < 0.05) were found among the seven risk assessment methods. Consistency analysis revealed moderate agreement between the Chinese synthesis index and exposure index methods (k = 0.571, p < 0.01). Conclusion: The Chinese synthesis and exposure index methods from Technical Guide GBZ/T 289-2017 are practical and reliable for assessing n-Hexane exposure risks in small and micro printing enterprises. Cleaning and printing roles were found to be at the highest risk for n-Hexane exposure. These findings provide valuable insights for targeted risk management strategies to protect workers' health in the industry.
Assuntos
Hexanos , Exposição Ocupacional , Impressão , Humanos , China , Medição de Risco , Exposição Ocupacional/análise , Saúde Ocupacional , Poluentes Ocupacionais do Ar/análiseRESUMO
Textile printing and dyeing wastewater is a substantial source of highly toxic halogenated pollutants because of the chlorination decolorization. However, information on the occurrence and fate of the highly toxic halogenated byproducts, which are produced by chlorination decolorization of the textile printing and dyeing wastewater, is very limited. In this study, the occurrence of six categories of halogenated byproducts (haloacetic acids (HAAs), haloacetonitriles (HANs), N-nitrosamines (NAs), trihalomethanes, halogenated ketones, and halonitromethanes) was investigated along the full-scale treatment processes of textile printing and dyeing wastewater treatment plants. Furthermore, the ecological risk of the halogenated byproducts was evaluated. The results showed that the total concentration of halogenated byproducts increased significantly after chlorination. Large amounts of HAAs (average 122.1 µg/L), HANs (average 80.9 µg/L), THMs (average 48.3 µg/L), and NAs (average 2314.3 ng/L) were found in the chlorinated textile wastewater, and the results showed that the generations of HANs and NAs were positively correlated with the BIX and ß/α index, indicating that the HANs and NAs might form from the microbial metabolites. In addition, HAAs and HANs exhibited high ecological risk quotients (>1), suggesting their high potential ecological risk. The results also demonstrated that most halogenated byproducts could be effectively removed by reverse osmosis treatment processes except NAs, with a lower removal rate of 18%. This study is believed to provide an important theoretical basis for controlling and reducing the ecological risks of halogenated byproducts in textile printing and dyeing wastewater effluents.
Assuntos
Halogenação , Águas Residuárias , Poluentes Químicos da Água , Águas Residuárias/química , Poluentes Químicos da Água/química , Medição de Risco , Indústria Têxtil , Impressão , Corantes/química , TêxteisRESUMO
In indoor air the reaction of ozone (O3) with terpenes may lead to the formation of irritating gas-phase products which may induce acute airway effects (i.e. sudden, short-term changes or symptoms related to the respiratory system). We aimed to perform an in vitro study on possible health effects of products from the O3-initiated reaction of limonene with printer exhaust, representing real-life mixtures in offices. Human bronchial epithelial cells were exposed for 1 hour (h) to limonene and O3, combined with printer exhaust. The resulting concentrations represented 34% and 6% of the generated initial concentrations of limonene (400 µg/m³) and O3 (417 µg/cm³), respectively, which were in range of high end realistic indoor concentrations. We observed that the reaction of limonene with O3 generated an increase of ultrafine particles within 1 h, with a significant increase of secondary reaction products 4-oxopentanal and 3-isopropenyl-6-oxo-heptanal at high end indoor air levels. Simultaneous printing activity caused the additional release of micron-sized particles and a further increase in reaction products. Relevant cellular endpoints to evaluate the possible induction of acute airway effects were measured. However, none of the test atmospheres representing office air was observed to induce these effects.
Assuntos
Poluição do Ar em Ambientes Fechados , Limoneno , Ozônio , Ozônio/química , Ozônio/toxicidade , Limoneno/química , Humanos , Poluição do Ar em Ambientes Fechados/análise , Células Epiteliais/efeitos dos fármacos , Oxirredução , Terpenos/química , Terpenos/toxicidade , Poluentes Atmosféricos/toxicidade , Poluentes Atmosféricos/química , Cicloexenos/química , Impressão , Linhagem Celular , Material Particulado/toxicidade , Material Particulado/químicaRESUMO
Lateral flow assay (LFA) color signal quantification methods were developed by utilizing both International Commission on Illumination (CIE) LAB (CIELAB) color space and grayscale intensity differences. The CIELAB image processing procedure included calibration, test, control band detection, and color difference calculation, which can minimize the noise from the background. The LFA platform showcases its ability to accurately discern relevant colorimetric signals. The rising occurrence of infectious outbreaks from foodborne pathogens like Salmonella typhimurium presents significant economic, healthcare, and public health risks. The study introduces an aptamer-based lateral flow (ABLF) platform by using inkjet printing for specially detecting S. typhimurium. The ABLF utilized gold-decorated polystyrene microparticles, functionalized with specific S. typhimurium aptamers (Ps-AuNPs-ssDNA). The platform demonstrates a detection limit of 102 CFU mL-1 in buffer solutions and 103 CFU mL-1 in romaine lettuce tests. Furthermore, it sustained performance for over 8 weeks at room temperature. The ABLF platform and analysis methods are expected to effectively resolve the low-sensitivity problems of the former LFA systems and to bridge the gap between lab-scale platforms to market-ready solutions by offering a simple, cost-effective, and consistent approach to detecting foodborne pathogens in real samples.
Assuntos
Aptâmeros de Nucleotídeos , Colorimetria , Ouro , Nanopartículas Metálicas , Salmonella typhimurium , Salmonella typhimurium/isolamento & purificação , Colorimetria/métodos , Colorimetria/instrumentação , Ouro/química , Aptâmeros de Nucleotídeos/química , Nanopartículas Metálicas/química , Limite de Detecção , Microbiologia de Alimentos , Lactuca/microbiologia , Lactuca/química , Impressão , Poliestirenos/química , Técnicas Biossensoriais/métodosRESUMO
Excessive or burst generation of reactive oxygen species (ROS) can induce oxidative stress, precipitating a range of critical illnesses, including cancers, Parkinson's disease and Ischemia-reperfusion injury. Conventional biological assays for ROS, involving discrete steps of capturing, labelling, and spectrometric detection, are complex and time-intensive. Moreover, their accuracy is substantially compromised by the short lifespan (microseconds to milliseconds) of ROS. Consequently, there is a pressing need for a rapid and efficient method that enables real-time detection. In this study, we have developed a printable, flexible ROS sensor based on a robust nanoenzyme composite by direct deposition of the paste onto a flexible polyethylene terephthalate (PET) substrate. This device demonstrated the fast and real-time responses to the hydrogen peroxide (mimetic agent) in the laboratory and to total ROS in sweat of an individual, exhibiting an outstanding current response to hydrogen peroxide across a broad concentration range of 0.01-10 mM, with a limit of detection (LOD) of 1.85 µM. The device's sensitivity to hydrogen peroxide (136.59 µA mM-1 cm-2), was found to be 1.5 to 10 times higher than that of sensors previously reported. Moreover, the IFRS device successfully identified instantaneous ROS levels in the sweat of adult males in vitro, with amperometric response increased 8 times after half an hour strenuous exercise, thereby exhibiting excellent selectivity, remarkable stability, and confirmed high biosafety. Overall, the IFRS provides a viable and practical solution for simple, expedited, and real-time ROS detection in the near future.
Assuntos
Peróxido de Hidrogênio , Polietilenotereftalatos , Espécies Reativas de Oxigênio , Suor , Humanos , Espécies Reativas de Oxigênio/análise , Espécies Reativas de Oxigênio/metabolismo , Suor/química , Peróxido de Hidrogênio/análise , Peróxido de Hidrogênio/química , Polietilenotereftalatos/química , Técnicas Biossensoriais/métodos , Masculino , Materiais Biocompatíveis/química , Técnicas Eletroquímicas/métodos , Limite de Detecção , Impressão , AdultoRESUMO
OBJECTIVES: This study aimed to document adverse health effects among office, copy, and print shop workers using the Nano-Control, International Foundation Survey. METHODS: Self-reported information on 16 health outcomes and three surrogate exposure variables were collected from 1998 individuals between 1999 and 2010. Logistic regression models, adjusted for age, gender, and smoking status, assessed the association between printer exposure and health symptoms. RESULTS: Among the participants, 61.9% were office workers, 5.5% were technicians, and 23.3% held other professions. Technicians had a higher risk for cancer compared to office workers (odds ratio [OR], 2.5; P < 0.01). Visible toner dust exposure was associated with chronic fatigue (OR, 9.6; P < 0.01), bronchial hyperresponsiveness (OR, 5.1; P < 0.01), cardiovascular diseases (OR, 3.6; P < 0.01), asthma, allergies, and other diseases (OR range, 1.4-3.2; P < 0.01). CONCLUSIONS: The increased chronic and acute health risks among these workers warrant further investigations of causal associations.
Assuntos
Doenças Profissionais , Exposição Ocupacional , Autorrelato , Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Adulto , Exposição Ocupacional/efeitos adversos , Doenças Profissionais/epidemiologia , Doenças Profissionais/etiologia , Neoplasias/epidemiologia , Poeira , Impressão , Asma/epidemiologia , Doenças Cardiovasculares/epidemiologia , Fadiga/epidemiologia , Hipersensibilidade/epidemiologia , Hipersensibilidade/etiologia , Hiper-Reatividade Brônquica/epidemiologia , Hiper-Reatividade Brônquica/etiologia , Processos de Cópia , Modelos Logísticos , Adulto JovemRESUMO
How did Victorian print forms shape experiences of pregnancy? This article focuses on pregnancy calendars, a form that rose to prominence in nineteenth-century Britain and Europe. Such calendars appeared in tabular as well as circular formats and were printed in books, periodicals and pocketbooks designed for both medical practitioners and fertile women. These calendars shaped the nebulous period of human gestation, giving pregnancy narrative form by dividing it temporally into stages and highlighting key events and medical interventions. In the nineteenth century, these printed pregnancy calendars mediated between women's personal experiences and gestational body time as well as medical management of that time. During this period, such calendars-which included the columnar reckoning table as well as the circular periodoscope-functioned as instruments of both medical control and female agency. Although they did not enable pregnant women to critique the medicalisation of pregnancy, they nevertheless accorded to such women some power in managing their reproductive bodies.
Assuntos
Impressão , Humanos , Gravidez , Feminino , História do Século XIX , Reino Unido , Europa (Continente) , Impressão/história , Gestantes/psicologiaRESUMO
BACKGROUND: Precise localized printing of plasmonic nanoparticles at desired locations can find a plethora of applications in diverse areas, including nanophotonics, nanomedicine, and microelectronics. The focused laser beam-assisted optical printing technique has illustrated its potential for the localized printing of differently shaped plasmonic particles. However, the technique is either time-consuming or often requires focused optical radiation, limiting its practical applications. While the optothermal printing technique has recently emerged as a promising technique for the direct and rapid printing of plasmonic nanoparticles onto transparent substrates at lower laser intensities, its potential to print the plasmonic nanoparticles to the core of the optical fiber platforms and utilize it for biological cell trapping as well as an analytical platform remains unexplored. RESULTS: Herein, we demonstrate the thermal-convection-assisted printing of the Ag plasmonic nanoparticles from the plasmonic colloidal solution onto the core of single-mode optical fiber and its multi-functional applications. The direct printing of plasmonic structure on the fiber core via the thermal-convection mechanism is devoid of the requirement of any additional chemical ligand to the fiber core. Further, we demonstrated the potential of the developed plasmonic fiber probe as a multifunctional surface-enhanced Raman spectroscopic (SERS) platform for sensing, chemical reaction monitoring, and single-cell studies. The developed SERS fiber probe is found to detect crystal violet in an aqueous solution as low as 100 pM, with a plasmonic enhancement of 107. Additionally, the capability of the fiber-tip platform to monitor the surface plasmon-driven chemical reaction of 4-nitrothiophenol (4NTP) dimerizing into p, p'-dimercaptoazobenzene (DMAB) is demonstrated. Further, the versatility of the fiber probe as an effective platform for opto-thermophoretic trapping of single biological cells such as yeast, along with its Raman spectroscopic studies, is also shown here. SIGNIFICANCE: In this study, we illustrate for the first time the optothermal direct printing of plasmonic nanoparticles onto the core of a single-mode fiber. Further, the study demonstrates that such plasmonic nanoparticle printed fiber tip can act as a multi-functional analytical platform for optothermally trap biological particles as well as monitoring plasmon-driven chemical reactions. In addition, the plasmonic fiber tip can be used as a cost-effective SERS analytical platform and is thus expected to find applications in diverse areas.
Assuntos
Nanopartículas Metálicas , Fibras Ópticas , Prata , Análise de Célula Única , Análise Espectral Raman , Análise Espectral Raman/métodos , Nanopartículas Metálicas/química , Prata/química , Compostos de Sulfidrila/química , Fenóis/análise , Fenóis/química , Humanos , ImpressãoRESUMO
In this paper, paper microfluidic channel fabricated by directly screen-printing of polydimethylsiloxane (PDMS) is proposed for paper spray mass spectrometry analysis of therapeutic drugs in the blood samples. Compared with traditional paper spray, PDMS-printed paper spray (PP-PS) allows fluid to flow to the tip of paper with less sample loss which significantly improved the signal intensity of target compounds in blood samples. As paper can reduce the matrix effect, PP-PS also has a greater advantage than electro-spray Ionization (ESI) when directly analyzing complex biological sample in terms of the detection efficiency. Linearity and limits of detection (LOD) were evaluated for five psychotropic drugs: olanzapine, quetiapine, 9-hydroxyrisperidone, clozapine, risperidone. As a result, PP-PS improved the signal intensity of the psychotropic drugs at a concentration of 250 ng/ml in blood samples by a factor of 2-5 times and lowered the relative standard deviation (RSD) by a factor of 2-5.6 times compared with traditional paper spray. And PP-PS also improved signal intensity by a factor of 9-33 times compared with ESI. Quantitative experiments of PP-PS mass spectrometry indicated that the linear range was 5-500 ng/ml and the LOD were improved by a factor of 5-71 times for all these drugs compared with traditional paper spray. In addition, PP-PS was applied to the home-made miniaturized mass spectrometer and the precursor ions of all five psychotropic drugs (250 ng/ml) in the mass spectrometry results were obtained as well. These could prove that PP-PS has the potential to analyze complex biological samples in application on the miniaturized mass spectrometer which can be used outside the laboratory.
Assuntos
Dimetilpolisiloxanos , Espectrometria de Massas , Papel , Humanos , Dimetilpolisiloxanos/química , Espectrometria de Massas/métodos , Limite de Detecção , Clozapina/sangue , Risperidona/sangue , Fumarato de Quetiapina/sangue , Palmitato de Paliperidona/sangue , Olanzapina/sangue , Psicotrópicos/sangue , ImpressãoRESUMO
In recent years, consumer preferences have begun to turn back to natural dyes, whereas synthetic dyes have been pushed into the background over the previous 60 years. This is a result of increased knowledge of the potential hazards associated with the creation of synthetic dyes, which use raw materials derived from petrochemicals and involve intense chemical interactions. Such dyes need a lot of energy to produce, and their negative effects on the environment increase pollution. It has been discovered that several of these dyes, particularly the azo-based ones are carcinogenic. On the contrary, natural dyes are getting more attention from scientists and researchers as a result of their several advantages like being eco-friendly, biodegradable and renewable, sustainable, available in nature, having no disposal problems, minimizing the consumption of fossil fuel, anti-bacterial, insect repellent, and anti-allergic, anti-ultraviolet, intensify dyeing and finishing process efficiency, less expensive, and no adverse effects on human health and environment. However, there are also some drawbacks, like poor fastness properties, natural dye printing for bulk production, difficulties in reproducibility of shades, and so forth. Despite all these limitations, the demand for natural dyes is increasing significantly in textile industries because they offer far more safety than synthetic dyes. This study provides an overall concept of the natural dyes in textile printing. It illustrates parameters of printing performance, methods, and techniques of extraction of natural dyes, printing methods, and printing of natural and synthetic fibers. Finally, this study describes the challenges and future prospects of natural dyes in textile printing.
Assuntos
Corantes , Têxteis , Corantes/química , Impressão , Indústria TêxtilRESUMO
Single-cell analysis by mass spectrometry (MS) is emerging as a powerful tool that not only contributes to cellular heterogeneity but also offers an unprecedented opportunity to predict pathology onset and facilitates novel biomarker discovery. However, the development of single-cell MS analysis techniques with a focus on sample extraction, separation, and ionization methods for volume-limited samples and complexity of cellular samples are still a big challenge. In this study, we present a high-throughput approach to inkjet drop on demand printing single-cell MS for rapid screening of biomarkers of polycyclic aromatic hydrocarbon (PAH) exposure at the KYSE-150 cell, aiming to elucidate the pathogenesis of PAH-induced esophageal cancer. With an analytical bulk KYSE-150 cell throughput of up to 51 cells per minute, the method provides a new opportunity for simultaneous single-cell analysis of multiple biomarkers. We screened 930 characteristic ions from 3,683 detected peak signals and identified 91 distinctive molecules that exhibited significant differences under various concentrations of PAH exposure. These molecules have potential as clinical diagnostic biomarkers. Additionally, the current study identifies specific biomarkers that behave completely opposite in single-cell and multicell lipidomics as the concentration of PAH changes. These biomarkers potentially subdivide KYSE-150 cells into PAH-sensitive and PAH-insensitive types, providing a basis for revealing PAH toxicity and disease pathogenesis from the heterogeneity of cellular metabolism.
Assuntos
Espectrometria de Massas , Hidrocarbonetos Policíclicos Aromáticos , Análise de Célula Única , Hidrocarbonetos Policíclicos Aromáticos/análise , Humanos , Biomarcadores/metabolismo , Biomarcadores/análise , Linhagem Celular Tumoral , Impressão , Biomarcadores Tumorais/metabolismo , Biomarcadores Tumorais/análiseRESUMO
In the present study, biosynthesized ZnO nanoparticles in food wastewater extract (FWEZnO NPs) was used in the photocatalytic degradation of real samples of printing ink wastewater. FWEZnO NPs were prepared using green synthesis methods using a composite food waste sample (2 kg) consisted of rice 30%, bread 20 %, fruits 10 %, chicken 10 %, lamb 10%, and vegetable 20%. The photocatalysis process was optimized using response surface methodology (RSM) as a function of time (15-180 min), pH 2-10 and FWEZnO NP (20-120 mg/100 mL), while the print ink effluent after each treatment process was evaluated using UV-Vis-spectrophotometer. The behaviour of printing ink wastewater samples for photocatalytic degradation and responses for independent factors were simulated using feed-forward neural network (FFNN). FWEZnO NPs having 62.48 % of the purity with size between 18 and 25 nm semicrystalline nature. The main functional groups were -CH, CH2, and -OH, while lipid, carbon-hydrogen stretching, and amino acids were the main component in FWEZnO NP, which contributed to the adsorption of ink in the initial stage of photocatalysis. The optimal conditions for printing ink wastewater were recorded after 17 min, at pH 9 and with 20 mg/100 mL of FWEZnO NPs, at which the decolorization was 85.62 vs. 82.13% of the predicted and actual results, respectively, with R2 of 0.7777. The most significant factor in the photocatalytic degradation was time and FWEZnO NPs. The FFNN models revealed that FWEZnO NPs exhibit consistency in the next generation of data (large-scale application) with an low errors (R2 0.8693 with accuracy of 82.89%). The findings showing a small amount of catalyst is needed for effective breakdown of dyes in real samples of printing ink wastewater.
Assuntos
Tinta , Redes Neurais de Computação , Águas Residuárias , Óxido de Zinco , Óxido de Zinco/química , Águas Residuárias/química , Nanopartículas Metálicas/química , Poluentes Químicos da Água/análise , Catálise , Impressão , Eliminação de Resíduos Líquidos/métodos , AlimentosRESUMO
Nanogenerators possess the capability to harvest faint energy from the environment. Among them, thermoelectric (TE), triboelectric, piezoelectric (PE), and moisture-enabled nanogenerators represent promising approaches to micro-nano energy collection. These nanogenerators have seen considerable progress in material optimization and structural design. Printing technology has facilitated the large-scale manufacturing of nanogenerators. Although inks can be compatible with most traditional functional materials, this inevitably leads to a decrease in the electrical performance of the materials, necessitating control over the rheological properties of the inks. Furthermore, printing technology offers increased structural design flexibility. This review provides a comprehensive framework for ink-based nanogenerators, encompassing ink material optimization and device structural design, including improvements in ink performance, control of rheological properties, and efficient energy harvesting structures. Additionally, it highlights ink-based nanogenerators that incorporate textile technology and hybrid energy technologies, reviewing their latest advancements in energy collection and self-powered sensing. The discussion also addresses the main challenges faced and future directions for development.
Assuntos
Tinta , Nanotecnologia , Nanotecnologia/métodos , Fontes de Energia Elétrica , Reologia , Impressão/métodosRESUMO
In order to fulfill the demands for degradability, a broad working range, and heightened sensitivity in flexible sensors, biodegradable polyurethane (BTPU) was synthesized and combined with CNTs to produce BTPU/CNTs coated cotton fabric using an ultrasonic-assisted inkjet printing process. The synthesized BTPU displayed a capacity for degradation in a phosphate buffered saline solution, resulting in a weight loss of 25 % after 12 weeks of degradation. The BTPU/CNTs coated cotton fabric sensor achieved an extensive strain sensing range of 0-137.5 %, characterized by high linearity and a notable sensitivity (gauge factor (GF) of 126.8). Notably, it demonstrated a low strain detection limit (1 %), rapid response (within 280 ms), and robust durability, enabling precise monitoring of both large and subtle human body movements such as finger, wrist, neck, and knee bending, as well as swallowing. Moreover, the BTPU/CNTs coated cotton fabric exhibited favorable biocompatibility with human epidermis, enabling potential applications as wearable skin-contact sensors. This work provides insight into the development of degradable and high sensing performance sensors suitable for applications in electronic skins and health monitoring devices.