Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 70
Filtrar
1.
A A Pract ; 14(9): e01287, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32909713

RESUMO

Methemoglobinemia is a rare disorder of the blood in which there is an increase in methemoglobin, which occurs when hemoglobin is present in the oxidized form. Methemoglobin impairs hemoglobin's ability to transport oxygen, produces functional anemia, and leads to tissue hypoxia. We report the successful management of a case of refractory hypoxia due to acutely acquired methemoglobinemia in a patient undergoing treatment for coronavirus disease 2019 (COVID-19) pneumonia. The cause of methemoglobinemia in this patient remains unknown. Hypoxia and methemoglobinemia did not respond to methylene blue and required administration of packed red blood cell transfusions.


Assuntos
Infecções por Coronavirus/complicações , Hipóxia/etiologia , Metemoglobinemia/complicações , Pneumonia Viral/complicações , Insuficiência Respiratória/etiologia , Injúria Renal Aguda/complicações , Injúria Renal Aguda/terapia , Idoso , Anticorpos Monoclonais Humanizados/uso terapêutico , Antioxidantes/uso terapêutico , Ácido Ascórbico/uso terapêutico , Betacoronavirus , COVID-19 , Infecções por Coronavirus/tratamento farmacológico , Corynebacterium , Infecções por Corynebacterium/complicações , Infecções por Corynebacterium/terapia , Síndrome da Liberação de Citocina/complicações , Inibidores Enzimáticos/uso terapêutico , Transfusão de Eritrócitos , Hematínicos/uso terapêutico , Humanos , Hidroxocobalamina/uso terapêutico , Hidroxicloroquina/uso terapêutico , Hipóxia/terapia , Masculino , Metemoglobinemia/terapia , Azul de Metileno/uso terapêutico , Pandemias , Pneumonia Bacteriana/complicações , Pneumonia Bacteriana/terapia , Pneumonia Viral/tratamento farmacológico , Terapia de Substituição Renal , Insuficiência Respiratória/terapia , SARS-CoV-2 , Choque Séptico/complicações
2.
Infection ; 48(3): 413-420, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32185636

RESUMO

PURPOSE: Corynebacterium spp. (C. spp.) is commonly considered as a contaminant in respiratory specimens. No study has ever focused on its clinical relevance in the lower respiratory tract of patients admitted to the intensive care unit (ICU) and requiring mechanical ventilation. The aims were to describe the characteristics of ICU patients with a C. spp. positive deep respiratory specimen, to investigate the impact of C. spp. on the occurrence of pneumonia, and to evaluate the outcomes of these pneumonia. METHODS: We retrospectively included all adult patients admitted to ICU in a 1000-bed University Hospital (2007-2017) who had a C. spp. positive lower respiratory tract specimen at a significant quantitative level. We used clinical, radiological, and microbiological criteria to classify the likelihood of such pneumonia. RESULTS: Among the 31 patients included, acute respiratory failure and postoperative care after major surgery were the main reasons of admission. SAPS II was 47 [34-60]. C. spp. pneumonia was considered as probable, possible and unlikely in 10, 14, and 7 patients, respectively. Fifty-two and 94% of C. spp. strains were sensitive to amoxicillin, and vancomycin/linezolid, respectively. Seventeen patients had a complete course of antibiotic against C. spp. The overall ICU mortality was 58%. CONCLUSION: Corynebacterium spp seems to be responsible for authentic pneumonia in mechanically ventilated patients. It should be considered as clinically relevant when predominantly present in respiratory specimen from patients suspected with pneumonia in ICU, and empirically treated.


Assuntos
Infecções por Corynebacterium/terapia , Corynebacterium/isolamento & purificação , Unidades de Terapia Intensiva/estatística & dados numéricos , Pneumonia/mortalidade , Respiração Artificial/estatística & dados numéricos , Infecções Respiratórias/terapia , Idoso , Estudos de Coortes , Infecções por Corynebacterium/microbiologia , Estado Terminal/epidemiologia , Estado Terminal/terapia , Feminino , França/epidemiologia , Mortalidade Hospitalar , Humanos , Masculino , Pessoa de Meia-Idade , Pneumonia/microbiologia , Infecções Respiratórias/microbiologia , Estudos Retrospectivos
3.
J Clin Pathol ; 73(8): 445-453, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-32094275

RESUMO

Cystic neutrophilic granulomatous mastitis (CNGM) is a rare subtype of granulomatous mastitis with a highly distinct histological pattern often associated with Corynebacterium species. CNGM is characterised by suppurative lipogranulomas that are composed of central lipid vacuoles rimmed by neutrophils and an outer cuff of epithelioid histiocytes. Some of the lipid vacuoles may contain sparse, rod-shaped, gram-positive bacilli that can be easily missed or dismissed. The surrounding mixed inflammatory infiltrate contains Langhans-type giant cells, lymphocytes and neutrophils. CNGM occurs in reproductive age women with a history of pregnancy and typically presents as a palpable mass that can be painful. CNGM has many mimickers, most significantly breast carcinoma. In many cases, CNGM has significant pathological and clinical overlap with other forms of granulomatous mastitis. Given the association with Corynebacterium species, early diagnosis of CNGM is essential in offering patients the most appropriate treatment. Prolonged antibiotic therapy specifically directed to corynebacteria is required, sometimes even beyond resolution of clinical symptoms. This comprehensive review of the existing literature on CNGM describes clinical-pathological features, microbiological findings, challenges associated with the microscopic differential diagnosis, clinical implications of this diagnosis and emerging treatment options. Morphological criteria and suggested comments to convey the degree of diagnostic certainty are also proposed for standard pathology reporting.


Assuntos
Infecções por Corynebacterium/patologia , Mastite Granulomatosa/patologia , Neutrófilos/patologia , Adulto , Neoplasias da Mama/diagnóstico , Infecções por Corynebacterium/terapia , Diagnóstico Diferencial , Feminino , Células Gigantes de Langhans/patologia , Mastite Granulomatosa/microbiologia , Mastite Granulomatosa/terapia , Humanos , Linfócitos/patologia , Neutrófilos/microbiologia
4.
Medicine (Baltimore) ; 99(3): e18761, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-32011462

RESUMO

INTRODUCTION: Corynebacterium striatum is common contaminant in clinical specimens. Here, we report a rare case of pyogenic tenosynovitis of the wrist caused by C striatum in a dermatomyositis patient taking oral immunosuppressants. PATIENT CONCERNS: A 67-year-old Japanese woman with dermatomyositis had a history of multiple intraarticular injections of corticosteroids to the right wrist joint for the treatment of osteoarthritis. She was admitted to our hospital with a painful lump on the right dorsal wrist lasting for three months. MRI revealed cellulitis of the dorsum of the right wrist and hand and fluid collection in the extensor tendon sheath. C striatum was detected in the cultures of three samples of synovial fluid taken from the dorsal hand. DIAGNOSIS: Pyogenic tenosynovitis of the wrist due to C striatum. INTERVENTIONS: The infection was successfully controlled with synovectomy and adjuvant antibiotic therapy. OUTCOMES: There has been no sign of recurrence for 12-months after the surgical treatment. LESSONS: This is the first reported case of pyogenic tenosynovitis due to C striatum in a patient with dermatomyositis. Clinicians should be aware that patients undergoing immunosuppressive therapy have a risk of C striatum infection.


Assuntos
Infecções por Corynebacterium/microbiologia , Corynebacterium , Dermatomiosite/microbiologia , Tenossinovite/microbiologia , Idoso , Terapia Combinada , Infecções por Corynebacterium/terapia , Dermatomiosite/tratamento farmacológico , Feminino , Humanos , Imunossupressores/uso terapêutico , Tenossinovite/terapia
5.
Curr Opin Obstet Gynecol ; 31(5): 325-332, 2019 10.
Artigo em Inglês | MEDLINE | ID: mdl-30946032

RESUMO

PURPOSE OF REVIEW: Corynebacterium kroppenstedtii is a difficult pathogen associated with granulomatous mastitis and recurrent breast abscesses. Despite over a dozen studies, there is no guidance on surgical interventions, steroid use, or dosing or duration of antibiotic treatment. RECENT FINDINGS: Initially seen in predominantly Maori and Pacific Islander multiparous, postlactating women, C. kroppenstedtii breast infection has since been reported throughout the world, including in nulliparous women. Additionally, emerging data suggest that hyperprolactinemia is a modifiable risk factor for these infections. This article reviews a patient case and data from 87 other cases to compile current best practices for diagnosis, treatment, and monitoring, and provides areas for future study. SUMMARY: In cases of granulomatous mastitis and breast abscess, especially if recurrent, infection with C. kroppenstedtii should be considered. Microbiologists should be alerted to the specialized growth conditions and tools needed for appropriate culturing, identification, and antibiotic susceptibility testing. Clinicians should utilize a multimodal approach with surgical and antibiotic treatment to maximize clinical cure and reduce recurrence.


Assuntos
Abscesso/microbiologia , Infecções por Corynebacterium/microbiologia , Mastite Granulomatosa/microbiologia , Abscesso/diagnóstico , Abscesso/terapia , Adulto , Antibacterianos/uso terapêutico , Corynebacterium/isolamento & purificação , Infecções por Corynebacterium/diagnóstico , Infecções por Corynebacterium/terapia , Drenagem/métodos , Feminino , Mastite Granulomatosa/diagnóstico , Mastite Granulomatosa/terapia , Humanos
6.
Can J Urol ; 26(1): 9680-9682, 2019 02.
Artigo em Inglês | MEDLINE | ID: mdl-30797252

RESUMO

Corynebacterium urealyticum is an organism associated with a rare chronic urinary tract infection, which can lead to calcification of the urinary tract and promote rapid lithogenesis. This case illustrates the serious complications that can arise from chronic infection with C. urealyticum, which include rapid progression of luminal and parenchymal urinary tract calcification and concomitant renal failure. This case and a review of the literature demonstrate the need for an increased awareness of this organism with early identification, aggressive management, and test of cure that may help avoid the sequela of these infections.


Assuntos
Infecções por Corynebacterium/complicações , Corynebacterium , Infecções Urinárias/complicações , Infecções por Corynebacterium/diagnóstico , Infecções por Corynebacterium/terapia , Humanos , Índice de Gravidade de Doença , Infecções Urinárias/diagnóstico , Infecções Urinárias/terapia
9.
Mem. Inst. Oswaldo Cruz ; 113(9): e180051, 2018. graf
Artigo em Inglês | LILACS | ID: biblio-955124

RESUMO

Multidrug-resistant (MDR) Corynebacterium striatum has been cited with increased frequency as pathogen of nosocomial infections. In this study, we report the draft genome of a C. striatum isolated from a patient with bloodstream infection in a hospital of Rio de Janeiro, Brazil. The isolate presented susceptibility only to tetracycline, vancomycin and linezolid. The detection of various antibiotic resistance genes is fully consistent with previously observed multidrug-resistant pattern in Corynebacterium spp. A large part of the pTP10 plasmid of MDR C. striatum M82B is present in the genome of our isolate. A SpaDEF cluster and seven arrays of CRISPR-Cas were found.


Assuntos
Humanos , Infecção Hospitalar/transmissão , Genoma/genética , Infecções por Corynebacterium/terapia , Brasil/epidemiologia
10.
Rinsho Ketsueki ; 58(11): 2250-2255, 2017.
Artigo em Japonês | MEDLINE | ID: mdl-29212977

RESUMO

A 54-year-old woman with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) underwent hematopoietic stem cell transplantation from an HLA-matched sibling. Subsequently, she suffered from chronic graft versus host disease (GvHD) and received medical treatment. Fever developed on day 697 and resulted in a shock state at 10 h after the visit. Achromobacter xylosoxidans was detected in the initial blood culture on day 699. General conditions exacerbated even after the start of meropenem hydrate (MEPM, Meropen®) administration, with Corynebacterium striatum detected as an additional species in the initial blood culture on day 701. Although vancomycin hydrochloride (VCM, Vancomycin®) was administered, the conditions did not improve. She died on day 702. Between January 2012 and December 2016, A. xylosoxidans was detected only in nine cases in our hospital, which included five with hematological malignancies and only one (present) with sepsis. At the same time, Corynebacterium species were detected in blood cultures from 39 cases in our hospital, which included 31 with hematological malignancies. Some reports on drug-resistant A. xylosoxidans and C. striatum have been published. Infections with these species may become fatal when complicated by sepsis in immunocompromised patients with hematological malignancies. More cases should be accumulated for detailed investigation.


Assuntos
Achromobacter denitrificans , Infecções por Corynebacterium/terapia , Infecções por Bactérias Gram-Negativas/terapia , Cromossomo Filadélfia , Leucemia-Linfoma Linfoblástico de Células Precursoras/terapia , Corynebacterium , Evolução Fatal , Feminino , Doença Enxerto-Hospedeiro/tratamento farmacológico , Transplante de Células-Tronco Hematopoéticas , Humanos , Pessoa de Meia-Idade , Transplante Homólogo
11.
Dtsch Med Wochenschr ; 142(21): 1609-1612, 2017 Oct.
Artigo em Alemão | MEDLINE | ID: mdl-29046006

RESUMO

History and clinical findings We report on three patients suffering from skin and soft tissue infections of the legs due to toxigenic Corynebacterium ulcerans strains. In all three patients, there was a predisposition due to chronic diseases. Three patients had domestic animals (cat, dog) in their households. Investigations and diagnosis A mixed bacterial flora including Corynebacterium ulcerans was found in wound swab samples. Diphtheric toxin was produced by the Corynebacterium ulcerans strains in all three cases. Treatment and course In all three patients, successful handling of the skin and soft tissue infections was possible by combining local treatment with antibiotics. Diphtheria antitoxin was not administered in any case. Conclusion Based on a review of the recent literature pathogenesis, clinical symptoms and signs, diagnostics and therapy of skin and soft tissue infections due to Corynebacterium ulcerans are discussed. Corynebacterium ulcerans should be considered as a potential cause of severe skin and soft tissue infections. Occupational or domestic animal contacts should be evaluated.


Assuntos
Infecções por Corynebacterium/microbiologia , Dermatopatias Bacterianas/microbiologia , Infecções dos Tecidos Moles/microbiologia , Idoso de 80 Anos ou mais , Animais , Animais Domésticos , Toxinas Bacterianas/biossíntese , Corynebacterium/classificação , Corynebacterium/metabolismo , Infecções por Corynebacterium/complicações , Infecções por Corynebacterium/diagnóstico , Infecções por Corynebacterium/terapia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Dermatopatias Bacterianas/complicações , Dermatopatias Bacterianas/diagnóstico , Dermatopatias Bacterianas/terapia , Infecções dos Tecidos Moles/complicações , Infecções dos Tecidos Moles/diagnóstico , Infecções dos Tecidos Moles/terapia
12.
Orbit ; 36(5): 344-346, 2017 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-28700261

RESUMO

Corynebacterium amycolatum is a saprophyte gram-positive bacillus of the skin flora. It has been linked to diverse infections in immunocompromised patients and also of different types of prostheses. However, to our knowledge, there are no reports on its ability to produce ocular infections or to grow over alloplastic materials for orbital surgery. We present a case of orbital implant exposure including pure isolation of C. amycolatum. The patient was referred for discharge in his socket. After removal of the artificial eye, a large area of implant exposure and signs of chronic infection were observed. A microbiological sample was taken by rubbing the implant with a sterile swab. The sample was cultured and C. amycolatum was identified by phenotypical characterization. Other microbial species were not isolated. Besides being able to adhere to cardiac and joint devices, this case shows that C. amycolatum is a potential infectious agent of orbital prostheses. Pure isolation of C. amycolatum in an ocular sample is extremely rare and suggests an etiological role of this microorganism in an ocular or periocular infection.


Assuntos
Infecções por Corynebacterium/microbiologia , Corynebacterium/isolamento & purificação , Infecções Oculares Bacterianas/microbiologia , Implantes Orbitários/microbiologia , Infecções Relacionadas à Prótese/microbiologia , Adulto , Infecções por Corynebacterium/diagnóstico , Infecções por Corynebacterium/terapia , Remoção de Dispositivo , Evisceração do Olho , Infecções Oculares Bacterianas/diagnóstico , Infecções Oculares Bacterianas/terapia , Humanos , Masculino , Testes de Sensibilidade Microbiana , Polietileno , Infecções Relacionadas à Prótese/diagnóstico , Infecções Relacionadas à Prótese/terapia
13.
Ear Nose Throat J ; 96(1): E33-E36, 2017 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-28122110

RESUMO

As the treatment of hematopoietic cancers evolves, otolaryngologists will see a higher incidence of opportunistic infections. We discuss a case of invasive fungal disease that invaded the larynx, pharynx, trachea, and pulmonary parenchyma after chemotherapy. The patient, a 46-year-old woman, presented 1 week after undergoing induction chemotherapy. Her initial symptoms were odynophagia and dysphagia. Despite encouraging findings on physical examination, her health rapidly declined and she required an urgent tracheotomy and multiple operations to address spreading necrosis. Because of her inability to heal, she was not a candidate for laryngectomy, so she was treated with conservative management. The patient was then lost to follow-up, but she returned 5 months later with laryngeal destruction and a complete laryngotracheal separation. While noninvasive fungal laryngitis is routinely encountered, its invasive counterpart is rare. The literature demonstrates that some cases completely resolve with medical therapy alone but that surgery is necessary in others. We recommend surgical debridement of all necrotic tissue.


Assuntos
Infecções por Bactérias Gram-Positivas/complicações , Hospedeiro Imunocomprometido/imunologia , Infecções Fúngicas Invasivas/complicações , Laringite/complicações , Abscesso Pulmonar/complicações , Faringite/complicações , Antibacterianos/uso terapêutico , Antifúngicos/uso terapêutico , Aspergilose/complicações , Aspergilose/imunologia , Aspergilose/terapia , Candidíase/complicações , Candidíase/imunologia , Candidíase/terapia , Coinfecção/complicações , Coinfecção/imunologia , Coinfecção/terapia , Infecções por Corynebacterium/complicações , Infecções por Corynebacterium/imunologia , Infecções por Corynebacterium/terapia , Desbridamento , Transtornos de Deglutição/etiologia , Disfonia/etiologia , Feminino , Infecções por Bactérias Gram-Positivas/imunologia , Infecções por Bactérias Gram-Positivas/terapia , Humanos , Quimioterapia de Indução/efeitos adversos , Infecções Fúngicas Invasivas/imunologia , Infecções Fúngicas Invasivas/terapia , Laringite/imunologia , Laringite/terapia , Leucemia Mieloide Aguda/complicações , Leucemia Mieloide Aguda/tratamento farmacológico , Abscesso Pulmonar/imunologia , Abscesso Pulmonar/terapia , Pessoa de Meia-Idade , Síndromes Mielodisplásicas/complicações , Síndromes Mielodisplásicas/tratamento farmacológico , Faringite/imunologia , Faringite/terapia , Tomografia Computadorizada por Raios X , Traqueotomia
15.
Am Surg ; 82(4): 362-8, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-27097631

RESUMO

Hidradenitis suppurativa (HS) is characterized by chronic inflammation, recurrent abscesses, and scarring. Surgery is performed when medical management and antibiotic therapy fails. This study sought to evaluate the demographics, surgical procedures, bacteriology, pharmacologic intervention, and quality of life of patients with recalcitrant HS requiring surgical intervention. A retrospective chart review was performed of 76 recalcitrant HS patients at the University of Illinois Medical Center. Patient demographics, bacterial culture, and surgery data were reviewed. Quality of life was assessed using the 36-item short-form health survey. Patients were mostly female (73.7%) and African American (81.6%) with a mean duration of symptoms of 8.6 years before surgery. Patients underwent at least one surgical procedure, most often to the axillae (57.6%) and 73.7 per cent received antibiotics. The most common culture isolates were Corynebacterium species (14.0%), Staphylococcus epidermidis (13.1%), and Staphylococcus aureus (10.4%) with varying resistance patterns. Surveyed patients had depressed 36-item short-form health survey physical functioning and social functioning scores. Recalcitrant HS patients with progressive symptomology over approximately nine years before surgical intervention were more likely to be African American women with axillary HS. Quality of life was diminished. We recommend initial treatment of HS with clindamycin and trimethoprim-sulfamethoxazole in clindamycin refractory cases.


Assuntos
Infecções por Corynebacterium , Hidradenite Supurativa , Infecções Estafilocócicas , Adolescente , Adulto , Negro ou Afro-Americano , Idoso , Antibacterianos/uso terapêutico , Axila/cirurgia , Terapia Combinada , Infecções por Corynebacterium/diagnóstico , Infecções por Corynebacterium/etnologia , Infecções por Corynebacterium/terapia , Demografia , Feminino , Hidradenite Supurativa/diagnóstico , Hidradenite Supurativa/etnologia , Hidradenite Supurativa/microbiologia , Hidradenite Supurativa/terapia , Humanos , Illinois/epidemiologia , Masculino , Pessoa de Meia-Idade , Avaliação de Resultados da Assistência ao Paciente , Qualidade de Vida , Estudos Retrospectivos , Infecções Estafilocócicas/diagnóstico , Infecções Estafilocócicas/etnologia , Infecções Estafilocócicas/terapia , Adulto Jovem
16.
Am J Surg Pathol ; 39(10): 1440-7, 2015 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-26200100

RESUMO

Granulomatous lobular mastitis (GLM) is an uncommon condition that typically occurs in parous, reproductive-aged women and can simulate malignancy on the basis of clinical and imaging features. A distinctive histologic pattern termed cystic neutrophilic granulomatous mastitis (CNGM) is seen in some cases of GLM and has been associated with Corynebacterium infection. We sought to further characterize the clinical, imaging, and histopathologic features of CNGM by studying 12 cases and attempted to establish the relationship of this disease with Corynebacterium infection. Patients were women ranging in age from 25 to 49 years (median: 34 y), and all presented with a palpable mass that was painful in half of the cases. In 2 of 9 cases, imaging was highly suspicious for malignancy (BI-RADS 5). CNGM was characterized by lobulocentric granulomas with mixed inflammation and clear vacuoles lined by neutrophils within granulomas. Gram-positive bacilli were identified in 5/12 cases. In 4 patients, the disease process worsened after the diagnostic core biopsy, with the development of a draining sinus in 2 cases. No growth of bacteria was seen in any microbial cultures. No bacterial DNA was identified by 16S rDNA polymerase chain reaction for 1 case that showed gram-positive bacilli on histology. Patients were treated with variable combinations of surgery, antibiotics, and steroids. The time to significant resolution of symptoms ranged from 2 weeks to 6 months. Similar to other forms of GLM, CNGM can mimic malignancy clinically and on imaging. When encountered in a needle core biopsy sample, recognition of the characteristic histologic pattern and its possible association with Corynebacterium infection can help guide treatment.


Assuntos
Infecções por Corynebacterium/diagnóstico , Mastite Granulomatosa/diagnóstico , Neutrófilos/patologia , Adulto , Antibacterianos/uso terapêutico , Biópsia por Agulha Fina , Biópsia com Agulha de Grande Calibre , Terapia Combinada , Infecções por Corynebacterium/microbiologia , Infecções por Corynebacterium/patologia , Infecções por Corynebacterium/terapia , Feminino , Mastite Granulomatosa/microbiologia , Mastite Granulomatosa/patologia , Mastite Granulomatosa/terapia , Humanos , Mamografia , Pessoa de Meia-Idade , Neutrófilos/microbiologia , Valor Preditivo dos Testes , Fatores de Risco , Esteroides/uso terapêutico , Resultado do Tratamento , Ultrassonografia Mamária
17.
J Gynecol Obstet Biol Reprod (Paris) ; 44(7): 679-82, 2015 Sep.
Artigo em Francês | MEDLINE | ID: mdl-25721346

RESUMO

Granulomatous mastitis is a rare disease, often associated with Corynebacterium infection. It raises the problem of diagnosis of breast tumor with a fast evolution and inflammatory character. We report two cases of granulomatous mastitis with Corynebacterium. It concerns the clinical and radiological description, followed by the therapeutic alternatives and future of the patients. The clinical presentation is variable. The treatment consists in a surgical procedure of resection. The medical treatment based of corticosteroids also proves efficient. The association between Corynebacterium presence and this pathology seems frequent and needs a specific bacteriological search.


Assuntos
Infecções por Corynebacterium , Corynebacterium/patogenicidade , Mastite Granulomatosa , Adulto , Infecções por Corynebacterium/complicações , Infecções por Corynebacterium/microbiologia , Infecções por Corynebacterium/terapia , Feminino , Mastite Granulomatosa/etiologia , Mastite Granulomatosa/microbiologia , Mastite Granulomatosa/terapia , Humanos
18.
Respir Care ; 59(1): e5-8, 2014 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-23764866

RESUMO

Pseudomembranous necrotizing tracheitis is a rare cause of life-threatening central airway obstruction. Patients present with hoarseness, cough, dyspnea, wheezing, stridor, and occasionally with respiratory failure. Diagnosis requires a high index of suspicion, and should be confirmed with a comprehensive bronchoscopy and biopsy. For patients with signs and symptoms of airway obstruction, a therapeutic rigid bronchoscopy with mechanical debridement is recommended. We present a rare case of necrotizing tracheitis secondary to Corynebacterium species, which caused life-threatening airway obstruction in an adult.


Assuntos
Infecções por Corynebacterium/complicações , Corynebacterium , Traqueia/patologia , Traqueíte/microbiologia , Adulto , Obstrução das Vias Respiratórias/microbiologia , Infecções por Corynebacterium/terapia , Feminino , Humanos , Necrose/microbiologia
20.
Ocul Immunol Inflamm ; 21(6): 488-90, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23941569

RESUMO

Diphtheroids were generally regarded as nonpathogenic contaminants, but recent clinical studies have emphasized that they may cause serious systemic and ocular disease mostly in patients with underlying medical conditions. In this study we present a case report of acute onset endogenous endophthalmitis associated with heavy growth of diphtheroids on the culture of anterior chamber fluid sample in a 46-year-old man with uncontrolled diabetes mellitus. He did well after appropriate treatment and a functional vision was restored. This case highlights the importance of proper management for the outcomes of patients with endogenous endophthalmitis. It is also significant to be cautious about a life-threatening medical status in a patient with such presentation.


Assuntos
Infecções por Corynebacterium/microbiologia , Corynebacterium/isolamento & purificação , Endoftalmite/microbiologia , Infecções Oculares Bacterianas/microbiologia , Corpo Vítreo/microbiologia , Antibacterianos/uso terapêutico , Infecções por Corynebacterium/diagnóstico , Infecções por Corynebacterium/terapia , Diagnóstico Diferencial , Endoftalmite/diagnóstico , Endoftalmite/terapia , Infecções Oculares Bacterianas/diagnóstico , Infecções Oculares Bacterianas/tratamento farmacológico , Humanos , Masculino , Pessoa de Meia-Idade , Vitrectomia , Corpo Vítreo/patologia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...