Compounded drugs as an alternative to the therapeutical gaps of inborn errors of metabolism
Braz. J. Pharm. Sci. (Online)
; 59: e21109, 2023. tab, graf
Article
en En
| LILACS
| ID: biblio-1429952
Biblioteca responsable:
BR40.1
Ubicación: BR40.1
ABSTRACT
Abstract Inborn errors of metabolism are rare disorders with few therapeutic options for their treatments, which can make patients suffer with complications. Therefore, compounded drugs might be a promising option given that they have the ability of meeting the patient's specific needs, (i) identification of the main drugs described in the literature; (ii) proposal of compounding systems and (iii) calculation of the budgetary addition for the inclusion of these drugs into the Brazilian Unified Health System. The research conducted a literature review and used management data as well as data obtained from official Federal District government websites. The study identified 31 drugs for the treatment of inborn errors of metabolism. Fifty eight percent (58%) (18) of the medicines had their current demand identified, which are currently unmet by the local Health System. The estimated budget for the production of compounded drugs was of R$363,16.98 per year for approximately 300 patients. This estimated cost represents a budgetary addition of only 0.17% from the total of expenditures planned for drug acquirement. There is a therapeutic gap for inborn errors of metabolism and compounding pharmacies show potential in ensuring access to medicine therapy with a low-cost investment.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Contexto en salud:
1_ASSA2030
/
2_ODS3
Problema de salud:
1_medicamentos_vacinas_tecnologias
/
2_cobertura_universal
Asunto principal:
Preparaciones Farmacéuticas
/
Metabolismo
/
Errores Innatos del Metabolismo
Tipo de estudio:
Health_economic_evaluation
Idioma:
En
Revista:
Braz. J. Pharm. Sci. (Online)
Asunto de la revista:
Farmacologia
/
Teraputica
/
Toxicologia
Año:
2023
Tipo del documento:
Article
País de afiliación:
Brasil