Factors associated with surgical resection in patients with Crohn's disease: long-term evaluation
Acta cir. bras
; 39: e391924, 2024. tab, graf
Article
en En
| LILACS, VETINDEX
| ID: biblio-1556668
Biblioteca responsable:
BR68.1
Ubicación: BR68.1
ABSTRACT
Purpose:
To evaluate patient characteristics and factors associated with surgical resection in patients with Crohn's disease (CD).Methods:
An analysis was performed on data from 295 patients with CD in follow-up from 2001 to 2018. Medical record data comprised age, gender, location, behavior and duration of the CD, smoking, and extraintestinal manifestation. Patients were divided into two groups according to the presence or absence of surgical resection.Results:
Out of the 295 patients with CD, 155 underwent surgical resection (53.2% male, mean age 43.88 ± 14.35 years). The main indications for surgery were stenosis (44.5%), clinical intractability (15.5%), and intra-abdominal fistulas (15.5%). Smoking (p < 0.001), longer CD duration (p < 0.0001), ileo-colonic location (p = 0.003), stenosing behavior (p < 0.0001), and fistulizing behavior (p < 0.0001) were significantly associated with surgical resection. Initial use of biological was significantly more frequent in the group of patients without surgical resection (p < 0.001).Conclusions:
Patients with CD still frequently need surgical treatment. Smoking (current or past), longer disease time, stenosing and fistulizing behavior, and ileo-colonic localization in CD patients were associated with a higher risk of surgery. Awareness about factors associated with unfavorable outcome allows such patients to be treated more appropriately.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Enfermedades Inflamatorias del Intestino
/
Enfermedad de Crohn
/
Factores de Riesgo
Límite:
Humans
Idioma:
En
Revista:
Acta cir. bras
Asunto de la revista:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Año:
2024
Tipo del documento:
Article
País de afiliación:
Brasil