Mitochondria-rich cells changes induced by nitrite exposure in tambaqui (Colossoma macropomum Cuvier, 1818)
An. acad. bras. ciênc
; 89(2): 965-972, Apr.-June 2017. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-886701
Biblioteca responsable:
BR1.1
ABSTRACT
ABSTRACT The gill mitochondria-rich cells of the juvenile Amazonian fish Colossoma macropomum were analyzed using light and scanning and transmission electron microscopy after 96 h exposure to 0.04 and 0.2 mM nitrite. Although the number of mitochondria-rich cells decreased significantly in the lamellar epithelium, no decrease was found in the interlamellar region of the gill filament. Nitrite exposure caused significant reduction on the apical surface area of individual mitochondria-rich cells (p < 0.05), with a resulting reduction of the fractional area of these cells in both the lamellar and filament epithelium. Swelling of endoplasmic reticulum cisternae, nuclear envelope and mitochondria were the main changes found in the mitochondria-rich cells. Cristae lysis and matrix vacuolization characterized the mitochondrial changes. The overall ultrastructural changes indicated cellular functional disruption caused by exposure to nitrite. The changes observed in the gill indicate that the cellular structures involved in the process of energy production become severely damaged by exposure to nitrite indicating irreversible damage conducting to cell death.
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
LILACS
Contexto en salud:
ODS3 - Salud y Bienestar
Tema en salud:
Meta 3.9: Reducir la cantidad de muertes producidas por químicos peligrosos y la contaminación del aire, agua y suelo
Asunto principal:
Muerte Celular
/
Exposición a Riesgos Ambientales
/
Characidae
/
Branquias
/
Mitocondrias
Límite:
Animales
Idioma:
Inglés
Revista:
An. acad. bras. ciênc
Asunto de la revista:
Ciencia
Año:
2017
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Federal do Amazonas/BR
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