Excreción de porfirinas e infección crónica por virus C de la hepatitis / Porphyrin excretion and chronic infection by hepatitis C virus

RESUMO

Eighteen patients with cirrhosis Child-Pough A, eight infected with hepatitis C virus, were studied. Urinary excretion of Ù aminolevulinic acid, porphobilinogen, coproporphyrins, uroporphyrins and fecal excretion of coproporphyrins and protoporphyrins were measured. Red blood cell protoporphyrin was also measured. There were no differences in the measured parameters between patients with or without hepatitis C virus infection. No patient had uroporphyrin excretion values over the normal range. Some patients had slight elevations in some parameters, but always below the values observed in porphyrias. In these group of patients, hepatitis C virus infection of its associated liver diasease do not cause detectable alterations in porphyrin metabolism