Ultrastructure of cranial nervs of rats inoculated with rabies virus
Arq. neuropsiquiatr
; 55(4): 680-6, dez. 1997. ilus
Article
en En
| LILACS
| ID: lil-209364
Biblioteca responsable:
BR1.1
RESUMO
The V and VII cranial nerves of rats inoculated with rabies virus were studied by electron microscopy. The results were compared with the same cranial nerves of rats inoculated with rabies virus but vaccinated against the disease. The findings are those of axonal degeneration and intense demyelination of the nerves of the group of rats not vaccinated. The vaccinated rats showed some ultrastructural irrelevant alterations when compared with the other group. The degreee of ultrastructural alterations found in the group of rats not vaccinated suggests that in rabies severe damage of the cranial nerves occurs and that this may be closely related to the clinical picture of the disease (hydrophobia). Furthermore, as far as the authors know, this has not been considered in the classic descriptions of rabies and it is possible that an immunologic process may take part in the demyelination observed in the present study.
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Colección:
01-internacional
Base de datos:
LILACS
Contexto en salud:
3_ND
Problema de salud:
3_neglected_diseases
/
3_zoonosis
Asunto principal:
Rabia
/
Virus de la Rabia
/
Nervio Trigémino
/
Nervio Facial
Límite:
Animals
Idioma:
En
Revista:
Arq. neuropsiquiatr
Asunto de la revista:
NEUROLOGIA
/
PSIQUIATRIA
Año:
1997
Tipo del documento:
Article