-Skin eruption after the first dose of antitubercular quadri-therapy: consideration of pyrazinamide-. / Eruption après une première prise d'une quadrithérapie antituberculeuse: penser au pyrazinamide.
Arch Pediatr
; 5(3): 289-90, 1998 Mar.
Article
en Fr
| MEDLINE
| ID: mdl-10327997
ABSTRACT
UNLABELLED We report a rash after the first dose of antituberculosis polytherapy which raises questions concerning procedures to be followed. CASE REPORT An 8-year-old child presented with a pruritic rash 1.5 hours after the first dose of isoniazide, rifampicine, pyrazinamide and ethambutol was simultaneously administered, which did not recur after successive re-administration of isoniazide and rifampicine. Pyrazinamide, which was re-administered last, induced a recurrence. Slower pyrazinamide re-administration allowed continuation of treatment. CONCLUSION:
A protocol for re-administration of the four drugs is suggested.
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Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
3_ND
Problema de salud:
3_neglected_diseases
/
3_tuberculosis
Asunto principal:
Pirazinamida
/
Tuberculosis Pulmonar
/
Erupciones por Medicamentos
/
Exantema
/
Antituberculosos
Tipo de estudio:
Guideline
Límite:
Child
/
Humans
/
Male
Idioma:
Fr
Revista:
Arch Pediatr
Año:
1998
Tipo del documento:
Article
País de afiliación:
Francia