Topical vasoactive cream in the treatment of erectile failure: a prospective, randomized placebo-controlled trial.
BJU Int
; 83(7): 810-1, 1999 May.
Article
en En
| MEDLINE
| ID: mdl-10368202
ABSTRACT
OBJECTIVE:
To repeat a previous study on the use of a topical treatment for erectile failure using a vasoactive cream. PATIENTS ANDMETHODS:
Fourteen patients with erectile failure who had previously responded to intracorporeal injection therapy were enrolled in a randomized placebo-controlled trial. They were given two topical applications, comprising either a cream containing aminophylline, isosorbide dinitrate and co-dergocrine mesylate, or a placebo cream of similar appearance containing no pharmacologically active ingredients. Each patient received 16 applications, eight of the active cream and eight placebo. The creams were applied alternatively on successive occasions and the results recorded.RESULTS:
The active cream, applied on 77 occasions, resulted in three good and 13 partial erections. The placebo cream, applied on 76 occasions, yielded four good and 13 partial erections.CONCLUSIONS:
We were unable to reproduce the successful results reported by others; in the present study the active cream performed no better than placebo.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Vasodilatadores
/
Nifedipino
/
Mesilatos Ergoloides
/
Impotencia Vasculogénica
/
Aminofilina
/
Isosorbida
Tipo de estudio:
Clinical_trials
/
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
BJU Int
Asunto de la revista:
UROLOGIA
Año:
1999
Tipo del documento:
Article
País de afiliación:
Sudáfrica