Biologically active triterpene saponins from callus tissue of Polygala amarella.
J Nat Prod
; 62(6): 923-6, 1999 Jun.
Article
en En
| MEDLINE
| ID: mdl-10395523
ABSTRACT
A new bioactive saponin (1), together with a known saponin (polygalasaponin XXVIII) has been isolated from the callus tissue culture of Polygala amarella. Based on spectroscopic data, especially direct and long-range heteronuclear 2D NMR analysis and on chemical transformations, the structure of 1 was elucidated as 3-O-beta-D-glucopyranosyl presenegenin-28-O-beta-D-galactopyranosyl-(1 --> 3)-beta-D-xylopyranosyl-(1 --> 4)-alpha-L-rhamnopyranosyl-(1 --> 2)-[beta-D-glucopyranosyl-(1 --> 3)]-beta-D-fucopyranoside. Both saponins showed significant immunological properties based on the enhancement of granulocyte phagocytosis in vitro.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ácido Oleanólico
/
Plantas Medicinales
/
Saponinas
/
Adyuvantes Inmunológicos
Límite:
Humans
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Nat Prod
Año:
1999
Tipo del documento:
Article
País de afiliación:
Francia