[The effects of exogenous actin-binding casein kinase injected into the oocytes and ova of the clawed toad]. / Effekty ékzogennoi aktinsviazyvaiushchei kazeinovoi kinazy, in''etsirovannoi v ootsity i iaitsa shportsevoi liagushki.

ABSTRACT

The effects of microinjections of exogenous casein kinase 2 on the structural organization of the maturing oocytes and eggs were studied in Xenopus laevis. Kinase inhibited the progesterone-stimulated oocyte maturation and induced dislocation of pigment granules. The morphological effect was shown to be dose-dependent. The results obtained are discussed in the light of the possible influence of casein kinase 2 on the organization of the cortical actin cytoskeleton through phosphorylation of actin-binding proteins.