Collagen-based biomaterials as 3D scaffold for cell cultures: applications for tissue engineering and gene therapy.
Med Biol Eng Comput
; 38(2): 211-8, 2000 Mar.
Article
en En
| MEDLINE
| ID: mdl-10829416
ABSTRACT
Many substances are used in the production of biomaterials metals (titanium), ceramics (alumina), synthetic polymers (polyurethanes, silicones, polyglycolic acid (PGA), polylactic acid (PLA), copolymers of lactic and glycolic acids (PLGA), polyanhydrides, polyorthoesters) and natural polymers (chitosan, glycosaminoglycans, collagen). With the rapid development in tissue engineering, these different biomaterials have been used as three-dimensional scaffolds and cell transplant devices. The principal biochemical and biological characteristics of the collagen-based biomaterials are presented, including their interactions with cells (fibroblasts), distinct from those of synthetic polymers, and their potential use in gene therapy through the formation of neo-organs or organoids.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Materiales Biocompatibles
/
Colágeno
Límite:
Humans
Idioma:
En
Revista:
Med Biol Eng Comput
Año:
2000
Tipo del documento:
Article
País de afiliación:
Francia