Is placebo response the same as drug response in panic disorder?
Am J Psychiatry
; 157(6): 1014-6, 2000 Jun.
Article
en En
| MEDLINE
| ID: mdl-10831487
ABSTRACT
OBJECTIVE:
The authors used seven definitions of response in panic disorder to compare patient-rated improvements in quality of life between patients with panic disorder who responded to sertraline and those who responded to placebo.METHOD:
They combined and examined data from two multicenter, randomized, double-blind, parallel-group, flexible-dose studies of panic disorder (N=302).RESULTS:
Significant differences in quality of life between patients who responded to sertraline and those who responded to placebo were apparent across all the definitions of clinical response.CONCLUSIONS:
Patients who respond to placebo in panic disorder treatment studies may show symptom relief but may not experience improvement in quality of life. Determinations of quality of life should be included as components of both standard clinical assessment and clinical treatment studies of patients with panic disorder.
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Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
1_ASSA2030
Problema de salud:
1_sistemas_informacao_saude
Asunto principal:
Efecto Placebo
/
Trastorno de Pánico
/
Inhibidores Selectivos de la Recaptación de Serotonina
/
Sertralina
Tipo de estudio:
Clinical_trials
/
Etiology_studies
/
Risk_factors_studies
Aspecto:
Patient_preference
Límite:
Humans
Idioma:
En
Revista:
Am J Psychiatry
Año:
2000
Tipo del documento:
Article
País de afiliación:
Estados Unidos