Successful treatment of Paecilomyces lilacinus endophthalmitis after foreign body trauma to the cornea.
Cornea
; 20(1): 109-11, 2001 Jan.
Article
en En
| MEDLINE
| ID: mdl-11188992
ABSTRACT
PURPOSE:
To report the successful treatment of a patient with Paecilomyces lilacinus endophthalmitis infection after foreign body (FB) trauma to the cornea.METHODS:
A 30-year-old man presented to us with a corneal abscess and iritis 2 months after removal of a metal corneal FB. Initial corneal biopsy culture was negative. Treatment with topical 5% natamycin, 0.9% fortified gentamycin, and 5% cephalothin hourly was commenced. As a result of developing signs of endophthalmitis, two more biopsies were taken, a week apart, from the vitreous and anterior chamber, successively. The last biopsy yielded positive microbiologic results of the specious Paecilomyces lilacinus. Intravitreal injection of 50 microg/0.5 mL of amphotericin was administered during the vitreal biopsy. Soon after isolating the specious Paecilomyces lilacinus, the following treatment was administered 200 mg of itraconazole bd by mouth, 5% topical natamycin every hour, 2 mg/mL of topical fluconazole every 2 hours, three anterior chamber injections of 0.35 mL of 0.1% fluconazole and two amphotericin B injections to the anterior chamber of 50 microg/0.5 mL each.RESULTS:
There appeared to be no sign of infection 6 months after initial treatment. A large, dense scar existed in the medial part of the cornea only. The pupil was secluded. The patient's visual acuity was 6/21. The eye was comfortable and all topical antifungal medication was ceased.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infección de Heridas
/
Paecilomyces
/
Infecciones Fúngicas del Ojo
/
Cuerpos Extraños en el Ojo
/
Endoftalmitis
/
Micosis
/
Antifúngicos
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Cornea
Año:
2001
Tipo del documento:
Article
País de afiliación:
Australia