A multicentre evaluation of a new filtration protocol for leucocyte depletion of high-haematocrit red blood cells collected by an automated blood collection system.
Vox Sang
; 81(2): 108-12, 2001.
Article
en En
| MEDLINE
| ID: mdl-11555470
ABSTRACT
BACKGROUND AND OBJECTIVES:
A multicentre trial was set up to evaluate the performance of a new leucodepletion protocol. MATERIALS ANDMETHODS:
Filtration at high haematocrit was started during collection of red blood cell (RBC) products by apheresis with Trima. SAG-M was added after filtration through the filter. Haematocrits and haemoglobin of the filtered RBCs were measured. Residual leucocytes were determined by Nageotte counting.RESULTS:
One-hundred and forty seven procedures were carried out. The haematocrit and haemoglobin contents were 57.3 +/- 3.0% and 55.1 +/- 4.3 g/unit, respectively. All products showed low residual leucocyte levels (< or = 0.75 x 106/unit; 99.31% < 1 x 106).CONCLUSION:
Immediate, on-line, high-haematocrit filtration of red cells collected on Trima resulted in leucoreduced RBCs, which met the AABB and Council of Europe criteria.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Recolección de Muestras de Sangre
/
Filtración
/
Hematócrito
/
Leucocitos
Tipo de estudio:
Clinical_trials
Límite:
Humans
Idioma:
En
Revista:
Vox Sang
Año:
2001
Tipo del documento:
Article
País de afiliación:
España