Structural analysis of the lipopolysaccharide from the nontypable Haemophilus influenzae strain SB 33.
Eur J Biochem
; 268(20): 5278-86, 2001 Oct.
Article
en En
| MEDLINE
| ID: mdl-11606189
ABSTRACT
The structure of the core region of the lipopolysaccharide (LPS) from the nontypable Haemophilus influenzae strain SB 33 was elucidated. The LPS was subjected to a variety of degradative procedures. The structures of the derived oligosaccharide products were established by monosaccharide and methylation analyses, NMR spectroscopy and mass spectrometry. These analyses revealed a series of related phosphocholine (PCho) containing structures differing in the number of hexose residues. The results pointed to each species containing a conserved phosphoethanolamine (PEtn) substituted heptose-containing trisaccharide inner-core moiety. The major LPS glycoforms were identified as 2-Hex, 3-Hex and 4-Hex species according to the number of hexose residues present.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Lipopolisacáridos
/
Haemophilus influenzae
Idioma:
En
Revista:
Eur J Biochem
Año:
2001
Tipo del documento:
Article
País de afiliación:
Canadá