Exploring gene-environment interactions: socioregional moderation of alcohol use.
J Abnorm Psychol
; 110(4): 625-32, 2001 Nov.
Article
en En
| MEDLINE
| ID: mdl-11727951
ABSTRACT
Examples of gene-environment interaction in human behavioral data are relatively rare; those that exist have used simple, dichotomous measures of the environment. The authors describe a model that allows for the specification of more continuous, more realistic variations in environments as moderators of genetic and environmental influences on behavior. Using data from a population-based Finnish twin study, the authors document strong moderating effects of socioregional environments on genetic and environmental influences on adolescent alcohol use, with nearly a five-fold difference in the magnitude of genetic effects between environmental extremes. The incorporation of specific environmental measures into genetically informative designs should prove to be a powerful method for better understanding the nature of gene-environment interaction and its contribution to the etiology of behavioral variation.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Consumo de Bebidas Alcohólicas
/
Ambiente
Tipo de estudio:
Screening_studies
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Abnorm Psychol
Año:
2001
Tipo del documento:
Article
País de afiliación:
Estados Unidos