Outbreak of poliomyelitis in Hispaniola associated with circulating type 1 vaccine-derived poliovirus.
Science
; 296(5566): 356-9, 2002 Apr 12.
Article
en En
| MEDLINE
| ID: mdl-11896235
ABSTRACT
An outbreak of paralytic poliomyelitis occurred in the Dominican Republic (13 confirmed cases) and Haiti (8 confirmed cases, including 2 fatal cases) during 2000-2001. All but one of the patients were either unvaccinated or incompletely vaccinated children, and cases occurred in communities with very low (7 to 40%) rates of coverage with oral poliovirus vaccine (OPV). The outbreak was associated with the circulation of a derivative of the type 1 OPV strain, probably originating from a single OPV dose given in 1998-1999. The vaccine-derived poliovirus associated with the outbreak had biological properties indistinguishable from those of wild poliovirus.
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Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
2_ODS3
Problema de salud:
2_enfermedades_transmissibles
Asunto principal:
Poliomielitis
/
Vacuna Antipolio Oral
/
Brotes de Enfermedades
/
Poliovirus
Tipo de estudio:
Risk_factors_studies
/
Screening_studies
Límite:
Adolescent
/
Animals
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
País/Región como asunto:
Caribe
/
Haiti
/
Republica dominicana
Idioma:
En
Revista:
Science
Año:
2002
Tipo del documento:
Article
País de afiliación:
Estados Unidos