Tandem termination signals: myth or reality?
FEBS Lett
; 514(1): 84-9, 2002 Mar 06.
Article
en En
| MEDLINE
| ID: mdl-11904187
ABSTRACT
In two Escherichia coli genomes, laboratory strain K-12 and pathological strain O157H7, tandem termination codons as a group are slightly over-represented as termination signals. Individually however, they span the range of representations, over, as expected, or under, in one or both of the strains. In vivo, tandem termination codons do not make more efficient signals. The second codon can act as a backstop where readthrough of the first has occurred, but not at the expected efficiency. UGAUGA remains an enigma, highly over-represented, but with the second UGA a relatively inefficient back up stop codon.
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Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
3_ND
Problema de salud:
3_neglected_diseases
/
3_zoonosis
Asunto principal:
Biosíntesis de Proteínas
/
Codón de Terminación
/
Escherichia coli
Idioma:
En
Revista:
FEBS Lett
Año:
2002
Tipo del documento:
Article
País de afiliación:
Nueva Zelanda