Placental peptides as markers of gestational disease.
Reproduction
; 123(4): 487-95, 2002 Apr.
Article
en En
| MEDLINE
| ID: mdl-11914111
ABSTRACT
The human placenta produces a wide range of important peptides, of which an intricate balance is required throughout pregnancy. In a gestational disease, this balance may be disturbed and the identification of such changes may be used to detect a particular pathology or to ascertain its severity. This review considers the role and association of various placental peptide markers associated with the major gestational diseases including intrauterine growth retardation, pre-term labour, pre-eclampsia, chromosomal disorders, gestational diabetes and trophoblastic disease. Potential markers that may prove more reliable and specific in their diagnostic value and that may be used for identifying patients at risk are also discussed. The importance of the new fields of genomics and proteomics in the future discovery of new peptide markers is illustrated.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Placenta
/
Complicaciones del Embarazo
/
Diagnóstico Prenatal
/
Sustancias de Crecimiento
/
Enfermedades Fetales
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Reproduction
Asunto de la revista:
MEDICINA REPRODUTIVA
Año:
2002
Tipo del documento:
Article
País de afiliación:
Reino Unido