Prevalence of hepatitis G virus infection in patients with liver diseases in Singapore.
Singapore Med J
; 43(2): 067-9, 2002 Feb.
Article
en En
| MEDLINE
| ID: mdl-11993892
ABSTRACT
The prevalence of hepatitis G virus (HGV) infection in patients with liver diseases in Singapore and its pathogenic role in these patients was studied. One hundred and forty-eight patients who had chronic hepatitis or acute non A-E hepatitis were studied. Presence of HGV RNA was determined by nested polymerase chain reaction of the 5'non-coding region of the virus in all the patients. Hepatitis G IgG antibody to the envelope (E2) antigen was tested with an enzyme immunoassay (Boehringer Mannheim, Singapore) in 76 of them. Most patients (93%) were ethnically Chinese, predominantly males (74%) and chronic hepatitis B (72%) patients. Others had chronic hepatitis C (19%) or cryptogenic cirrhosis (6%). Four patients had acute non A-E hepatitis. HGV RNA and anti-HGenv were present in 3.5% and 8.3% of those with chronic liver disease. HGV infection did not account for any of the acute non A-E hepatitis and most of the cryptogenic cirrhosis.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infecciones por Flaviviridae
/
Virus GB-C
/
Hepatitis Viral Humana
/
Hepatopatías
Tipo de estudio:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Asia
Idioma:
En
Revista:
Singapore Med J
Año:
2002
Tipo del documento:
Article
País de afiliación:
Singapur